1,721,069 research outputs found
Zinc and vitamin C deficiency in a newborn with low gestational age
No full textA premature with 24-week gestational age, fed by total parenteral nutrition and affected by ileo-umbilical stercoraceous fistula is reported. At the end of the second month the little baby presented the characteristic clinical features of acrodermatitis enteropathica. The latter responded rapidly to zinc supplementation. In the meantime the little baby presented a tumefaction of the left thigh, multiple ecchymoses, ulaemorrhagia and stomatitis. Thanks to vitamin C supplementation, the clinical features of avitaminosis C rapidly regressed. Unfortunately, the little baby died when aged 6 months due to the complications of necrotizing enterocolitis. To the best of our knowledge, this is the first case of simultaneous deficiency of vitamin C and zinc
Metabolomics Applications in Children: A Right Way to Go
Full text linkMetabolomics is a new science based on the study of the metabolome, representing the set of all the metabolites of a biological organism, which are the final products of its gene expression. Metabolomics appears to be a promising tool in perinatal studies, such as hypoxic–ischemic encephalopathy (HIE), intrauterine growth restriction (IUGR), congenital infections, genetic diseases, neonatal nutrition
Longitudinal evaluation of human β-defensins and tumor necrosis factor-α in stools of preterm and term newborns.
No full textPersistent nephrocalcinosis caused by neonatal subcutaneous fat necrosis: Therapeutic considerations
No full textNeonatal subcutaneous fat necrosis (NSFN) is a transient, self-healing skin disorder, characterized by nodules and plaques caused by subcutaneous necrosis. NSFN is rarely observed in full-term newborns infants with perinatal problems, especially asphyxia. The most important NSFN complication is hypercalcemia, a common condition that can have serious consequences leading to death. In this paper we describe a case of persistent nephrocalcinosis caused by an extensive neonatal subcutaneous fat necrosis, emphasizing the symptoms to suspect hypercalcemia. We also discuss the therapeutic interventions to restore the levels of serum calcium and prevent the deposition of calcium salts
- …
