299 research outputs found
L’écriture translingue des femmes. Espace de médiation interculturelle dans le contexte multilingue francophone
Les écritures translingues, par leur nature, mettent en valeur une expérience de l’entre-deux, de l’exil et de l’étrangeté typique de toute personne ayant comme langue maternelle une langue minoritaire. C’est le cas aussi « des territoires, comme les anciennes colonies, les zones frontalières [...], d’où il n’est pas nécessaire de s’éloigner pour vivre entre deux langues et pour se sentir en exil dans la sienne » (Montini, 2015 : 223). Nous allons présenter ici le cas de deux écrivaines innues, Naomi Fontaine et Natasha Kanapé Fontaine qui, vivant entre les langues, parviennent à créer par leur écriture translingue, narrative, poétique et théâtrale, de potentiels espaces de médiation interculturelle où peuvent se dessiner des parcours de réparation à la recherche d’une rencontre authentiquement renouvelée à l’intérieur de la société dans laquelle elles vivent
Hydration layers at the graphite-water interface: Attraction or confinement
Söngen H, Morais Jaques Y, Zivanovic L, et al. Hydration layers at the graphite-water interface: Attraction or confinement. Physical Review B. 2019;100:205410
A higher order method for input-affine uncertain systems
Uncertainty is unavoidable in modeling dynamical systems and it may be represented mathematically by differential inclusions. In the past, we proposed an algorithm to compute validated solutions of differential inclusions; here we provide several theo-retical improvements to the algorithm, including its extension to piecewise constant and sinusoidal approximations of uncertain inputs, updates on the affine approximation bounds and a generalized formula for the analytical error. The approach proposed is able to achieve higher order convergence with respect to the current state-of-the-art. We implemented the methodology in Ariadne, a library for the verification of continuous and hybrid systems. For evaluation purposes, we introduce ten systems from the literature, with varying degrees of nonlinearity, number of variables and uncertain inputs. The results are hereby compared with two state-of-the-art approaches to time-varying uncertainties in nonlinear systems.(c) 2022 Published by Elsevier Ltd
Dual antiplatelet therapy in secondary prevention of ischemic stroke: a ghost from the past or a new frontier? Stroke Res Treat. 2010 Dec 29;2010:427418.
Rigorous continuous evolution of uncertain systems
Uncertainty is unavoidable in modeling dynamical systems and it may be represented mathematically by differential inclusions. In the past, we proposed an algorithm to compute validated solutions of differential inclusions; here we provide several theoretical improvements to the algorithm, including its extension to piecewise constant and sinu- soidal approximations of uncertain inputs, updates on the affine approx- imation bounds and a generalized formula for the analytical error. In addition, we implemented the methodology in Ariadne, a library for the verification of continuous and hybrid systems. Then we evaluated ten systems with varying degrees of nonlinearity, number of variables and uncertain inputs. The results are hereby compared with two state-of- the-art approaches to time-varying uncertainties in nonlinear systems
National surveys of UK and Italian neonatal units highlighted significant differences in the use of non-invasive respiratory support
Aim: This study compared how non-invasive respiratory support (NRS) was provided in neonatal units in Italy and the UK. Methods: An NRS questionnaire was sent to tertiary neonatal centres, identified by national societies, from November 2015 to May 2016. Results: Responses were received from 49/57 (86%) UK units and 103/115 (90%) Italian units. NRS was started in the delivery room by 61% of UK units and 85% of Italian units. In neonatal intensive care units, 33% of UK units used nasal high-flow therapy (HFT) as primary support, compared to 3% in Italy. Nasal continuous positive airway pressure (CPAP) was used in 57% of UK units and 90% of Italian units. The commonest starting flow rate on nasal HFT for term and preterm infants was 6 L/min in the UK, while Italian units mainly used this flow for term infants. In the UK, 67% of units decreased nasal HFT by 1 L/min per day. In Italy, infants on nasal CPAP were weaned by 1 cm H 2 O per day in 39% of units. Conclusion: The way that NRS was managed for very preterm infants differed between the UK and Italy, reflecting a lack of evidence on optimal NRS and the use of local protocols
Targeted radiotherapy in the conditioning prior to haematopoietic stem cell transplantation: Results of a phase I trial using an yttrium-90-labelled anti-CD66 murine monoclonal antibody demonstrating consistently high BM uptake
Targeted radiotherapy in haematopoietic stem cell transplantation: results of a phase I trial using an Yttrium-90-labelled anti-CD66 murine monoclonal antibody demonstrating consistent BM targeting
A randomised placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer’s disease
Objective:to determine the effects of cholinergic treatment on the muscarinic receptor in patients with Alzheimer’s disease. Methods:12 patients with mild to moderate Alzheimer’s disease and six controls were studied. The patients underwent ADAS-COG psychometric assessment and SPECT brain imaging with 123I quinuclidinyl benzilate (QNB), to demonstrate the postsynaptic muscarinic M1 receptor, before being randomised in a double blind study to receive either an acetylcholinesterase inhibitor (donepezil) or placebo for four months. Following this, the ADAS-COG and the 123I-QNB receptor scan were repeated. The controls were imaged on one occasion only. All image analyses were undertaken using SPM99. Results:123I-QNB imaging showed a significant relation between baseline psychometric impairment and deficits on scanning. Both placebo and actively treated groups had reductions in 123I-QNB uptake. Greater reductions in receptor binding were demonstrated in the placebo group than in those receiving active treatment. Intraindividual reproducibility of the 123I-QNB imaging technique appeared highly robust. Conclusions:the results suggest that 123I-QNB uptake is better preserved in Alzheimer’s disease patients on cholinergic treatment than on placebo. Cholinergic treatment may play a neuroprotective role. Sequential 123I-QNB imaging seems to be a powerful tool in monitoring the response of these receptors to disease modifying treatments. <br/
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