107 research outputs found

    Action of extracellular proteases of aspergillus flavus and aspergillus ochraceus micromycetes on plasma hemostasis proteins

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    In this study, we investigated the properties of proteolytic enzymes of two species of Aspergillus, Aspergillus flavus 1 (with a high degree of pathogenicity) and Aspergillus ochraceus L-1 (a conditional pathogen), and their effects on various components of the hemostasis system (in vitro) in the case of their penetration into the bloodstream. We showed that micromycete proteases were highly active in cleaving both globular (albuminolysis) and fibrillar (fibrin) proteins, and, to varying degrees, they could coagulate the plasma of humans and animals (due to proteolysis of factors of the blood coagulation cascade) but were not able to coagulate fibrinogen. The proteases of both Aspergillus fully hydrolyzed thrombi in 120–180 min. Micromycetes did not show hemolytic activity but were able to break down hemoglobin

    Technical Physics Letters V. 27, I. 06

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    dc.description[en_US]Technical Physics Letters -- June 2001 Volume 27, Issue 6, pp. 441-528 Features of the Charge Transfer in Nanoporous Silicon and Silicon Oxide with Adsorbed Water E. N. Luk'yanova, S. N. Kozlov, V. M. Demidovich, and G. B. Demidovich pp. 441-443 Full Text: PDF (37 kB) A Quantum Loop in Magnetic Field and a Quantum Interference Rectifier V. A. Geiler and I. Yu. Popov pp. 444-446 Full Text: PDF (43 kB) The Electric Conductivity of a Laser Plasma Excited at a Ceramic Surface A. V. Gradoboev pp. 447-448 Full Text: PDF (35 kB) Adsorbed Molecules Form Ordered Structures on the Surface of Metals Exposed to an Electric Field S. V. Zaitsev pp. 449-450 Full Text: PDF (58 kB) The P���H���T Effects on the Electric Resistance and Magnetoresistance of La0.7Sr0.1Pb0.2MnO3 Single Crystal Films S. S. Kucherenko, V. P. Pashchenko, P. I. Polyakov, S. I. Khartsev, and V. A. Shtaba pp. 451-453 Full Text: PDF (48 kB) Cleavage in the K8 Glass under Submicrosecond Impact Loading Yu. V. Sud'enkov pp. 454-456 Full Text: PDF (89 kB) Stationary Regimes of the Turbulent Plasma Acceleration in a High-Current Magnetoplasmadynamic Thruster K. P. Kirdyashev and V. I. Brukhty pp. 457-459 Full Text: PDF (48 kB) Surface Resistance of Type II Superconductors: The Surface Barrier Effect N. V. Zhelezina and G. M. Maksimova pp. 460-462 Full Text: PDF (47 kB) Stochastic Synchronization and the Growth in Regularity of the Noise-Induced Oscillations D. �. Postnov, D. V. Setsinskii, and O. V. Sosnovtseva pp. 463-466 Full Text: PDF (68 kB) Specific Properties of the PZT-Based Thin-Film Capacitor Structures with Excess Lead Oxide V. P. Afanas'ev, G. N. Mosina, A. A. Petrov, I. P. Pronin, L. M. Sorokin, and E. A. Tarakanov pp. 467-469 Full Text: PDF (205 kB) Generation of High-Intensity Second Harmonics by Femtosecond Pulses T. M. Lysak and V. A. Trofimov pp. 470-472 Full Text: PDF (52 kB) Dynamics of the Transverse Oscillations of an Electron Beam in a Stellarator V. V. Dolgopolov and Yu. V. Kirichenko pp. 473-475 Full Text: PDF (44 kB) The Volume of Information as a Measure of the Chaos Synchronization A. V. Shabunin, V. V. Demidov, V. V. Astakhov, and V. S. Anishchenko pp. 476-479 Full Text: PDF (63 kB) Stability of the Interphase Boundary during the Crystallization of Eutectics A. P. Gus'kov pp. 480-483 Full Text: PDF (59 kB) Effect of Nitrogen Oxides on the Sulfur Dioxide Removal from Flue Gases Under the Action of Pulsed Electron Beams G. V. Denisov, D. L. Kuznetsov, Yu. N. Novoselov, and R. M. Tkachenko pp. 484-486 Full Text: PDF (42 kB) Experimental Investigation of the Interaction of Two Acoustic Shock Waves A. L. Surkaev, V. G. Kul'kov, and G. N. Talyzov pp. 487-488 Full Text: PDF (31 kB) In vivo Investigation of the Immersion-Liquid-Induced Human Skin Clearing Dynamics V. V. Tuchin, A. N. Bashkatov, �. A. Genina, Yu. P. Sinichkin, and N. A. Lakodina pp. 489-490 Full Text: PDF (35 kB) Sonoluminescence Generated by the Interaction of Two Ultrasonic Fields with Strongly Different Frequencies N. V. Dezhkunov pp. 491-494 Full Text: PDF (55 kB) Nitrogen Diffusion in a Subsurface Region of Ion-Implanted Molybdenum E. Yu. Zamalin and O. B. Bodnar' pp. 495-497 Full Text: PDF (37 kB) Laser-Controlled Synthesis of Nickel���Aluminum Intermetallic Compounds A. V. Kamashev, A. S. Panin, A. L. Petrov, and I. V. Shishkovskii pp. 498-499 Full Text: PDF (32 kB) The Effect of Annealing on the Photoacoustic and Photothermal Response of Al2O3���SiC���TiC Ceramics with Internal Stresses K. L. Muratikov, A. L. Glazov, V. I. Nikolaev, D. N. Rose, and D. E. Dumar pp. 500-503 Full Text: PDF (324 kB) On the Possibility of Suppressing the Saturation of Photoelectric Amplification of Weak Optical Emission in Semiconductors by Forming Near-Contact Variband Layers V. A. Kholodnov and A. A. Drugova pp. 504-507 Full Text: PDF (63 kB) A Mechanism of Chaotic Mixing in an Elementary Deterministic Flow M. V. Budyansky and S. V. Prants pp. 508-510 Full Text: PDF (41 kB) A Nonlinear Dynamics of Stimulated Phonon Emission in a Nonautonomous Acoustic Quantum Generator under Superlow-Frequency-Modulated Pumping Conditions D. N. Makovetskii pp. 511-514 Full Text: PDF (73 kB) On the Mechanisms of Nonlinear Optical Attenuation in Fullerene-Containing pi-Conjugated Organic Systems N. V. Kamanina pp. 515-518 Full Text: PDF (55 kB) A Bistable Optical Element Based on a Magnetic Grating V. A. Tabarin and G. A. Shadrin pp. 519-521 Full Text: PDF (42 kB) Trace Development Behind a Pulsed-Periodic Energy Source V. N. Zudov pp. 522-524 Full Text: PDF (59 kB) Nonparaxial Gaussian Beams: 3. Optical Vortices A. V. Volyar, V. G. Shvedov, T. A. Fadeeva, and E. A. Konshu pp. 525-528 Full Text: PDF (191 kB)dc.description.contributor[en_US]dc.description.contributor[en_US

    Technical Physics Letters V. 27, I. 06

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    Technical Physics Letters -- June 2001 Volume 27, Issue 6, pp. 441-528 Features of the Charge Transfer in Nanoporous Silicon and Silicon Oxide with Adsorbed Water E. N. Luk'yanova, S. N. Kozlov, V. M. Demidovich, and G. B. Demidovich pp. 441-443 Full Text: PDF (37 kB) A Quantum Loop in Magnetic Field and a Quantum Interference Rectifier V. A. Geiler and I. Yu. Popov pp. 444-446 Full Text: PDF (43 kB) The Electric Conductivity of a Laser Plasma Excited at a Ceramic Surface A. V. Gradoboev pp. 447-448 Full Text: PDF (35 kB) Adsorbed Molecules Form Ordered Structures on the Surface of Metals Exposed to an Electric Field S. V. Zaitsev pp. 449-450 Full Text: PDF (58 kB) The P–H–T Effects on the Electric Resistance and Magnetoresistance of La0.7Sr0.1Pb0.2MnO3 Single Crystal Films S. S. Kucherenko, V. P. Pashchenko, P. I. Polyakov, S. I. Khartsev, and V. A. Shtaba pp. 451-453 Full Text: PDF (48 kB) Cleavage in the K8 Glass under Submicrosecond Impact Loading Yu. V. Sud'enkov pp. 454-456 Full Text: PDF (89 kB) Stationary Regimes of the Turbulent Plasma Acceleration in a High-Current Magnetoplasmadynamic Thruster K. P. Kirdyashev and V. I. Brukhty pp. 457-459 Full Text: PDF (48 kB) Surface Resistance of Type II Superconductors: The Surface Barrier Effect N. V. Zhelezina and G. M. Maksimova pp. 460-462 Full Text: PDF (47 kB) Stochastic Synchronization and the Growth in Regularity of the Noise-Induced Oscillations D. É. Postnov, D. V. Setsinskii, and O. V. Sosnovtseva pp. 463-466 Full Text: PDF (68 kB) Specific Properties of the PZT-Based Thin-Film Capacitor Structures with Excess Lead Oxide V. P. Afanas'ev, G. N. Mosina, A. A. Petrov, I. P. Pronin, L. M. Sorokin, and E. A. Tarakanov pp. 467-469 Full Text: PDF (205 kB) Generation of High-Intensity Second Harmonics by Femtosecond Pulses T. M. Lysak and V. A. Trofimov pp. 470-472 Full Text: PDF (52 kB) Dynamics of the Transverse Oscillations of an Electron Beam in a Stellarator V. V. Dolgopolov and Yu. V. Kirichenko pp. 473-475 Full Text: PDF (44 kB) The Volume of Information as a Measure of the Chaos Synchronization A. V. Shabunin, V. V. Demidov, V. V. Astakhov, and V. S. Anishchenko pp. 476-479 Full Text: PDF (63 kB) Stability of the Interphase Boundary during the Crystallization of Eutectics A. P. Gus'kov pp. 480-483 Full Text: PDF (59 kB) Effect of Nitrogen Oxides on the Sulfur Dioxide Removal from Flue Gases Under the Action of Pulsed Electron Beams G. V. Denisov, D. L. Kuznetsov, Yu. N. Novoselov, and R. M. Tkachenko pp. 484-486 Full Text: PDF (42 kB) Experimental Investigation of the Interaction of Two Acoustic Shock Waves A. L. Surkaev, V. G. Kul'kov, and G. N. Talyzov pp. 487-488 Full Text: PDF (31 kB) In vivo Investigation of the Immersion-Liquid-Induced Human Skin Clearing Dynamics V. V. Tuchin, A. N. Bashkatov, É. A. Genina, Yu. P. Sinichkin, and N. A. Lakodina pp. 489-490 Full Text: PDF (35 kB) Sonoluminescence Generated by the Interaction of Two Ultrasonic Fields with Strongly Different Frequencies N. V. Dezhkunov pp. 491-494 Full Text: PDF (55 kB) Nitrogen Diffusion in a Subsurface Region of Ion-Implanted Molybdenum E. Yu. Zamalin and O. B. Bodnar' pp. 495-497 Full Text: PDF (37 kB) Laser-Controlled Synthesis of Nickel–Aluminum Intermetallic Compounds A. V. Kamashev, A. S. Panin, A. L. Petrov, and I. V. Shishkovskii pp. 498-499 Full Text: PDF (32 kB) The Effect of Annealing on the Photoacoustic and Photothermal Response of Al2O3–SiC–TiC Ceramics with Internal Stresses K. L. Muratikov, A. L. Glazov, V. I. Nikolaev, D. N. Rose, and D. E. Dumar pp. 500-503 Full Text: PDF (324 kB) On the Possibility of Suppressing the Saturation of Photoelectric Amplification of Weak Optical Emission in Semiconductors by Forming Near-Contact Variband Layers V. A. Kholodnov and A. A. Drugova pp. 504-507 Full Text: PDF (63 kB) A Mechanism of Chaotic Mixing in an Elementary Deterministic Flow M. V. Budyansky and S. V. Prants pp. 508-510 Full Text: PDF (41 kB) A Nonlinear Dynamics of Stimulated Phonon Emission in a Nonautonomous Acoustic Quantum Generator under Superlow-Frequency-Modulated Pumping Conditions D. N. Makovetskii pp. 511-514 Full Text: PDF (73 kB) On the Mechanisms of Nonlinear Optical Attenuation in Fullerene-Containing pi-Conjugated Organic Systems N. V. Kamanina pp. 515-518 Full Text: PDF (55 kB) A Bistable Optical Element Based on a Magnetic Grating V. A. Tabarin and G. A. Shadrin pp. 519-521 Full Text: PDF (42 kB) Trace Development Behind a Pulsed-Periodic Energy Source V. N. Zudov pp. 522-524 Full Text: PDF (59 kB) Nonparaxial Gaussian Beams: 3. Optical Vortices A. V. Volyar, V. G. Shvedov, T. A. Fadeeva, and E. A. Konshu pp. 525-528 Full Text: PDF (191 kB)Archived web conten

    Sorption of calcium ions by modified montmorillonite

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    Modified sorbents based on montmorillonite hydrosols were obtained. Sorption of calcium from various solutions was studied. The effect of pH and concentration of an alkaline agent on calcium sorption was determined. As opposed to using NaOH as the alkaline agent, the use of Na2CO3 resulted in formation of less stable colloidal particles in the solution and, therefore, the process of calcium separation occurred more intensively. Sorption of calcium ions increased with the increasing pH value and dosage of the montmorillonite hydrosol. Thus, the modified montmorillonite can be used for separation of calcium ions from aqueous solutions with simultaneous elimination of a suspended matter. © 2019 Author(s)

    Fast and cheap identification of elite aspen clones in the North-West of Russia using ISSR markers

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    In 2001–2006, several experimental aspen plantations were established in the North-West of Russia (Leningrad region). Three in vitro propagated elite aspen (Populus tremula L.) clones from the Kostroma Forest Research Station were used as the planting stock for plantations. The planting plans of some experimental plantations were lost, which made it impossible to identify the genetic lineages. 13-years old unknown aspen clones demonstrated prominent growth rates, and reliably overtook natural aspen coppice. ISSR markers were used for fast and cheap restoring of the missing planting plan of the experimental aspen plantation under study; as a result, progenies of three elite aspen clones were recognized. The best fast-growing and stem rot resistant aspen clones was identified and called “Kostroma”

    Adsorption-coagulation separation of cesium and strontium ions by intercalated aluminosilicates

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    Adsorption and coagulation properties of intercalated montmorillonites were studied in aqueous systems containing cesium and strontium ions. It was shown that cesium sorption results in formation of two monomolecular layers of this component on the surface of the montmorillonite. Adsorption of strontium occurs due to formation of monolayer in pores of the mineral. Besides adsorption, coagulation of the sorbent's particles was intensified. Slow mixing of the solution resulted in particles aggregation, formation of large aggregates and their sedimentation. It was shown that particles aggregation occurred due to decrease of the charge as a result of ions adsorption. Rate constants of the solid phase coagulation were calculated. It was determined for ions with equal electric charges that coagulating ability of the ion increased with the decrease of the radius of hydrated ion. © 2019 Author(s)

    The efficiency of therapy the piglets gastroenteritis with combination of enrofloxacin and phytosorbent hypericum perforatum l.

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    Pathology of the gastrointestinal takes the first place between all illnesses of internal organs of piglets. Piglet gastroenteritis is linked to various critical periods of their livelihood during which immunodeficiency disorders, activation of opportunistic microflora, intestinal dysbiosis appear. Uncontrollable use of antibacterial drugs causes the development of antibiotic resistance of bacterial pathogens. The research aims to study the efficiency of herbal sorbent Hypericum Perforatum L. in the context of complex therapy of acute piglets’ gastroenteritis. The therapy efficiency of herbal sorbent Hypericum Perforatum L. was studied in the context of complex therapy of 119 piglets. For the experiment were taken piglets of age 38,2±3,9 days, weight 6,6 ±0, 2 kg. Piglets of group I (n=51) having gastroenteritis were treating with the drug “Baytril” including enrofloxacin hydrochloride 10% as the active substance, dose 0,5 ml/10 kg of animals weight, which corresponds 5 mg/kg enrofloxacin hydrochloride intramuscularly, 1 time a day in 5 days. Piglets of the group II (n=68) having gastroenteritis were treating with the drug “Baytril” including enrofloxacin hydrochloride 10% as the active substance, dose 0,5 ml/10 kg of animals weight, which corresponds 5 mg/kg enrofloxacin hydrochloride intramuscularly, 1 time a day in 5 days with additional prescription of herbal sorbent Hypericum Perforatum L. in dose 2,0 g per os 1 time a day in 7 days. It was founded that combined therapy of piglet’s gastroenteritis using enrofloxacin hydrochloride and herbal sorbent Hypericum Perforatum L. leads to full recovery for 20,6% more frequently than therapy with enrofloxacin hydrochloride only. During the therapy of ill piglets with a combination of enrofloxacin hydrochloride and herbal sorbent Hypericum Perforatum L. the credible reduction of the phenomenon of the neutrophilic leukocytosis, increasing of the relative amount of T-lymphocytes, T-helpers, and B-lymphocytes, normalization of serum concentration of C-reactive protein, common protein and albumin was found. In the blood of ill animals treated with a combination of enrofloxacin hydrochloride and herbal sorbent Hypericum Perforatum L. comparing to piglets treated with enrofloxacin only the number of leukocytes in peripheral blood credibly reduced and the activity of T-and B-lymphocytes increased. These changes reflect credible anti-inflammatory and immunomodulating effects of the herbal sorbent based on Hypericum Perforatum L. in the treatment of piglet gastroenteritis. © 2020, Advanced Scientific Research. All rights reserved

    Impulsive practical synchronization of n-dimensional nonautonomous systems with parameter mismatch

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    summary:This paper is concerned with impulsive practical synchronization in a class of n-dimensional nonautonomous dynamical systems with parameter mismatch. Some simple yet general algebraic synchronization criteria are derived based on the developed practical stability theory on impulsive dynamical systems. A distinctive feature of this work is that the impulsive control strategy is used to make n-dimensional nonautonomous dynamical systems with parameter mismatch achieve practical synchronization, where the parameter mismatch likewise exist in both system parameters and external excitation ones, and the synchronization error bound can be estimated by an analytical expression. Subsequently, the obtained results are applied to a typical gyrostat system, and numerical simulations demonstrate the effectiveness of the criteria and the robustness of the control technique

    In Vivo Bone Tissue Engineering Strategies: Advances and Prospects

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    Reconstruction of critical-sized bone defects remains a tremendous challenge for surgeons worldwide. Despite the variety of surgical techniques, current clinical strategies for bone defect repair demonstrate significant limitations and drawbacks, including donor-site morbidity, poor anatomical match, insufficient bone volume, bone graft resorption, and rejection. Bone tissue engineering (BTE) has emerged as a novel approach to guided bone tissue regeneration. BTE focuses on in vitro manipulations with seed cells, growth factors and bioactive scaffolds using bioreactors. The successful clinical translation of BTE requires overcoming a number of significant challenges. Currently, insufficient vascularization is the critical limitation for viability of the bone tissue-engineered construct. Furthermore, efficacy and safety of the scaffolds cell-seeding and exogenous growth factors administration are still controversial. The in vivo bioreactor principle (IVB) is an exceptionally promising concept for the in vivo bone tissue regeneration in a predictable patient-specific manner. This concept is based on the self-regenerative capacity of the human body, and combines flap prefabrication and axial vascularization strategies. Multiple experimental studies on in vivo BTE strategies presented in this review demonstrate the efficacy of this approach. Routine clinical application of the in vivo bioreactor principle is the future direction of BTE; however, it requires further investigation for overcoming some significant limitations

    Antimicrobial activity of hypericum perforatum L.

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    The use of sorbents as application materials in the treatment of wounds and purulent lesions of soft tissues has been known since ancient times. The essence of application sorption is the separation of toxic metabolites, microbial cells and bacterial toxins from wounds and purulent cavities with direct contact of the sorbent with their surface. The immobilization of various pharmaceuticals on the sorbent allows you to get effective antimicrobial drugs that have simultaneously a wide range of actions. These properties are realized as the immobilized substances that released on it. We chose silicon dioxide (SiO2) as the matrix when creating the Hypericum Perforatum holed phytosorbent. When introducing the phytosorbent Hypericum Perforatum into the wound, silicon dioxide maintains the concentration of the phytopreparation at a therapeutic level for a long time. Phytosorbent of Hypericum Perforatum combines the sorption properties of the sorbent with the antimicrobial and antioxidant properties of Hypericum Perforatum. The article studies the antimicrobial activity of Hypericum’s Perforatum phytosorbent in relation to the main pathogens of purulent wounds in cows by the method of consecutive two-time serial breeding. It is established that the phytosorbent of Hypericum Perforatum has a pronounced antimicrobial effect against conditionally pathogenic bacteria, pathogens of purulent processes in cattle. So, the drug at concentrations of 3.9 mg / ml and higher inhibited growth of 100.0% of S. aureus cultures, at a concentration of 7.8 mg / ml and higher-100.0% of S. intermedius isolates. It should be noted that the phytosorbent of Hypericum Perforatum was also found active against S. epidermidis, S. pyogenes, S. uberis and S. faecalis (it suppresses the growth of bacteria of these species in concentrations of 3.9; 15.6; 31.3 and 15.6 mg/ml, respectively). The drug had slightly less antimicrobial activity against gram-negative flora of E. coli (in concentrations ≥ 62.5 mg / ml), P. aeruginosa (≥ 125 mg/ml), P. vulgaris (≥ 62.5 mg/ml), P. mirabilis (≥ 31.3 mg/ml) and C. albicans (≥ 62.5 mg/ml). © 2020, Advanced Scientific Research. All rights reserved
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