362 research outputs found
Edoardo Robino: lo visible y lo invisible
No full textIn this paper we will demonstrate the originality of the work of Edoardo Robino, an Italian artist which thought can’t be considered without his artistic production: sculpture and writing must be considered as a unity, as two sides of the same path of interpretation of reality. In the same way, in the thought of Robino nature and culture are not separate, but represent the two faces of a process in which man is involved from the start. Identity is also difference, and therefore is not suitable to deny the unity of nature and culture. This unity in difference has been investigated by the author from a structural point of view and forma the contemporary Philosophy of language, producing a procedure that can be interesting for the contemporary Aesthetics.En este artículo pretendemos demostrar la originalidad de la obra de Edoardo Robino, artista italiano cuyo pensamiento no se puede separar de su producción artística: escultura y escritura tienen que considerarse en su unidad, como dos aspectos del mismo camino de interpretación de la realidad. En el mismo sentido, en el pensamiento de Robino, naturaleza y cultura no van separadas, sino que representan las dos caras de un proceso en que el hombre está implicado desde el principio. La identidad es también diferencia, y es por lo tanto irrazonable negar la unidad de naturaleza y cultura. Esta unidad en la diferencia ha sido estudiada por el autor a partir del Estructuralismo y de la filosofía del lenguaje contemporánea y ha dado lugar a un procedimiento del pensar que tiene mucho interés para la Teoría estética actual
Test genetici di paternità in gravidanza : una scelta oppure un obbligo per l’operatore?
No full textThe rapid development of molecular diagnostic techniques in the last twenty years has
been followed by an ethical and regulatory adjustment which turned out to be difficult
and complex.
At the same time the media contribute to convey to the public the idea of a virtual absence
of limits, especially when dealing with genetic investigations, which often leads to an
unconscious violation of the same regulations. However it is not uncommon to observe
that these rules are sometimes violated with full consciousness.
This manuscript will analyse the issue of genetic paternity testing performed during
pregnancy in the light of the Italian legislation.
This study does not cover a full revision of the international legislation, but it could
become a starting point in order to discuss an issue which is currently credited with only
marginal consideration.
After reviewing the main analytical techniques and the legal status of the embryo, the
Authors revised the legal framework and the principles of the medical code of conduct
regarding genetic discrimination in relation to the Law n. 194/1978 (the Italian law
governing the voluntary termination of pregnancy in some specific situations).
The main point to consider is whether DNA paternity tests are legally allowed during
pregnancy.
In either case there are significant legal and ethical implications for the health care
professional when asked for prenatal paternity testing.
From this study emerges the need for a legal clarification aimed at standardising the
rules, avoiding arbitrary decisions
Il restauro della Madonna con Bambino e Santi proveniente dalla chiesa di San Pietro Apostolo di Vaccarile: ricerca di tensione costante tramite l’impiego di calamite e applicazione di un nuovo sistema di tensionamento elastico
No full textL'articolo da conto dell'intervento di restauro effettuato sul dipinto proveniente dalla città di Vaccarile e presenta inoltre un nuovo sistema per il tensionamento dei dipinti su tela con telaio elastico a molle
7 nicotinic receptors by the tryptophan metabolites, 5‐hydroxyindole and kynurenate in mouse brain
No full text
Release-enhancing presynaptic muscarinic and nicotinic receptors coexist and interact on dopaminergic nerve endings of rat nucleus accumbens
No full textAnalysis of 11 tetrameric STRs in wild boars for forensic purposes.
No full textSTR profiling of animal species has a wide range of applications, including forensic identification, wildlife
preservation, veterinary public health protection and food safety.We tested the efficacy of a multiplex PCRbased
assay including 11 porcine-specific tetrameric STRs in a population sample of wild boars (n = 142)
originating from Piedmont (North West Italy). Multiple deviations from Hardy–Weinberg expectations
were observed, mostly due to a reduction in observed heterozygosity indicative of a high degree of
inbreeding.A value of u of 0.046 and an inbreeding coefficient of 0.089 were estimated.Combined power of
discrimination and probability of exclusion values for the STR panel were 0.9999999999996 and 0.99989.
In order to test the suitability of themethod formeat traceability purposes, adomestic pig referencesample
(n = 412), consisting of commercial lines commonly used in the meat production process, was also typed. A
Bayesian cluster analysis carried out using the observed genotypes, showed a percentage of correct
subspecies assignment of individual samples of 0.974 for wild boars and 0.991 for pigs, thusdemonstrating
the usefulness of the multiplex STR-typing system for discrimination purposes
Runs of homozygosity are associated with staging of periodontitis in isolated populations
No full textPeriodontitis is a common inflammatory disease characterized by a complex etiology, which is the result of a combination of genetic and environmental factors. Genetic variants linked to the periodontitis disease were already investigated, however, little was known regarding the severity of this disease. Recently, long runs of homozygosity (ROH) were associated with several multifactorial diseases. Therefore, in our work, we tried to assess the role of ROH and periodontitis status. We found an association between the excess of homozygosity owing to ROH and staging of periodontitis. More in detail, the total amount of homozygosity owing to ROH is positively associated with an increased severity of periodontitis (P = 0.0001). Regression tree analysis showed the impact of ROH burden in discriminating individuals with mild periodontitis stages I and II and periodontitis stages III and IV (P 1). Among them, we found a total of 33 genes. Interestingly, some of these genes were previously associated with granulocyte or platelet measures, both linked to the onset and the progression of periodontal disease. Our results suggest the not only single variants association test could help to risk assessment but even individual genomic features; furthermore, our ROH mapping highlighted the possible role of multiple genes in periodontal development
FULMINANT HEPATITIS INDUCED BY HERPESVIRUS IN A COMMON WOMBAT (VOMBATUS URSINUS)
No full textA male 2-year-old Common wombat (Vombatus ursinus) suddenly began showing symptoms of inappetence, weight loss, polyuria and polydipsia. Blood collection revealed elevated liver enzymes, glucose, fructosamine and CK values, low WBC count and elevated serum molybdenum and copper values. Abdominal ultrasound showed hyperechoic and dissociated hepatic tissue, as well as dilated intestinal loops. Despite supportive therapy, the animal died three days after the onset of clinical signs. On necropsy, edematous lungs, cardiac muscle pale and friable, dilated and gas-filled intestinal loops, pale kidneys, splenomegaly and hepatomegaly, with extremely fragile hepatic tissue, were found. Histopathology revealed necrotizing, non-suppurative myocarditis with areas of myocardial fibrosis, type II crescentic glomerulonephritis and focal hepatic necrosis with mononuclear infiltration and complete structural dissociation. Liver sections showed scattered intranuclear viral inclusions within the necrotic areas, and anti-herpesvirus immunoperoxidase stain evidenced strong nuclear staining. Within these zones, residual hepatocytes had enlarged "ground glass" nuclei with margination of chromatin. These findings could be consistent with fulminant hepatic necrosis due to herpesvirus. Transmission electron microscopy revealed hexagonal 100-110 nm in diameter capsids within distorted nuclei of hepatocytes, in a central zone immediately surrounded by a thick band of dense chromatin or in a mixture of electron-dense material, marginated against the nuclear membrane, but not in the extracellular space. A nested Pan-herpesvirus PCR showed a positive fragment that will be sequenced to confirm the result. To the best of our knowledge, this is the first report of a herpesvirus induced hepatitis in the Common wombat outside his native area
- …
