56 research outputs found
Modellare i discenti : ottimizzare formazione, valutazione e testing
No full textGli autori stanno sperimentando una procedura innovativa per profilare gli utenti di una piattaforma di e-learning per predire chi porterà a termine il corso con successo e aiutare i tutor ad organizzare le loro mansioni fin dall’inizio. La modellazione predittiva dei discenti è proposta come uno strumento per programmare strategie di tutoraggio orientate all’individuo,
allo scopo di aumentare non solo le probabilità di completamento del corso ma anche il ritorno sugli investimenti della formazione. Infatti creando un proflo dei discenti è possibile sapere in anticipo chi tra loro terminerà il corso
con successo, chi abbandonerà comunque il corso e chi ha bisogno di più aiuto per completarlo. Il fatto di sapere dove i discenti siano più propensi ad avere successo aiuterà inoltre l’ottimizzazione della valutazione e della fase di formazione
Learner modelling : optimizing training, assessment and testing
No full textThe authors are experimenting an innovative procedure to profile learners
using an e-learning platform to predict if they will successfully end their
training (or education activities) and to help tutors organize their tasks from
the very beginning. Predictive learner modelling is proposed as an instrument
for planning individual-oriented tutoring strategies to increase not only the
probability of completion but also the return on investments of the training
activities. In fact, by modelling learners’ profiles it is possible to know in
advance who of them will successfully complete their courses, who will
leave the training anyway and who needs more help to complete their
courses, according to their profiles. Knowing where learners are more likely
to succeed will also help optimizing the assessment and training phases
The Golgi apparatus of satellite cells associated with spinal ganglion neurons: changes with age in the rabbit
No full textWe studied the Golgi apparatus in the satellite cell sheaths enveloping spinal ganglion neurons of rabbits aged 12, 42, and 79 months. We found neither structural changes nor indications of peripheral displacement of this organelle with advancing age. The mean percentage of cytoplasmic volume occupied by the Golgi apparatus decreased significantly passing from young adult to old rabbits. This decrease was only in very minor part a consequence of lipofuscin accumulation, so that the ratio between the total volume of the Golgi apparatus and the functionally active volume of cytoplasm decreased with age. The mean cytoplasmic volume of perineuronal satellite cell sheaths did not change significantly with increasing age, whereas the total volume of the Golgi apparatus within these sheaths decreased significantly with age. This decrease strongly suggests that the activity of satellite cells diminishes in old age, further suggesting that these cells are unable to compensate for the decrease in the neuronal metabolism that a number of authors have described in old age
Modificazioni quantitative dell’apparato di Golgi delle cellule satelliti dei gangli spinali nel corso dell’invecchiamento
No full textA mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.
No full textThe correct size of the different areas composing the mature cerebral cortex depends on the proper early allocation of cortical progenitors to their distinctive areal fates, as well as on appropriate subsequent tuning of their area-specific proliferation-differentiation profiles. Whereas much is known about the genetics of the former process, the molecular mechanisms regulating proliferation and differentiation rates within distinctive cortical proto-areas are still largely obscure. Here we show that a mutual stimulating loop, involving Emx2 and canonical Wnt signalling, specifically promotes expansion of the occipito-hippocampal anlage. Collapse of this loop occurring in Emx2-/- mutants leads progenitors within this region to slow down DNA synthesis and exit prematurely from the cell cycle, due to misregulation of cell cycle-, proneural- and lateral inhibition-molecular machineries, and eventually results in dramatic and selective size-reduction of occipital cortex and hippocampus. Reactivation of canonical Wnt signalling in the same mutants rescues a subset of molecular abnormalities and corrects differentiation rates of occipito-hippocampal progenitors
The Golgi apparatus of spinal ganglion neurons : quantitative changes with aging
No full textThe Golgi apparatus of spinal ganglion neurons was studied in 1, 3.6, 6.7, and 8.8-year-old rabbits. The structure of this organelle did not differ in the four age groups examined. While the mean volume of the neuronal perikaryon increased progressively with age, the total volume of the Golgi apparatus remained stable throughout life. As a consequence, the mean percentage of perikaryal volume occupied by this organelle decreased significantly with age. Since the percentage of perikaryal volume occupied by lipofuscin remained at low levels throughout life, the ratio of the total volume of the Golgi apparatus to the functionally active volume of cytoplasm decreased with age. It is possible that this decrease is related to the reduction in neuronal metabolism that occurs in senescence. The age-related quantitative changes in the Golgi apparatus were very similar in large light and in small dark neurons. Finally, neither fragmentation, nor peripheral displacement of the Golgi apparatus was observed with advancing age
Designing Meaningful Game Experiences for Rehabilitation and Sustainable Mobility Settings
No full textThis paper presents the approach followed in two ongoing research projects aimed to designing meaningful game-based experiences to support home rehabilitation, eco-sustainable mobility goals and more in general better daily lifestyles. We first introduce the need for designing meaningful game-based experiences that are well-connected to the relevant non-game settings and can be customized by/for users, then, we show examples of how this approach can be realized in the rehabilitation and sustainable mobility contexts
Business intelligence for strategic marketing : predictive modelling of customer behaviour using fuzzy logic and evolutionary algorithms
No full textThis paper describes an application of evolutionary algorithms to the predictive modelling of customer behaviour in a business environment. Predictive models are represented as fuzzy rule bases, which allows for intuitive human interpretability of the results obtained, while providing satisfactory accuracy. An empirical case study is presented to show the effectiveness of the approach
Proceedings of the 2nd Workshop on Awareness and Reflection in Technology-Enhanced Learning
No full textMoore, A., Pammer, V., Pannese, L., Prilla, M., Rajagopal, K., Reinhardt, W., Ullman, Th. D., & Voigt, Ch. (Eds.) (2012). Proceedings of the 2nd Workshop on Awareness and Reflection in Technology Enhanced Learning. In conjunction with the 7th European Conference on Technology Enhanced Learning: 21st Century Learning for 21st
Century Skills (ARTEL/EC-TEL 2012). September, 18, 2012, Saarbrücken, Germany. Available online
at http://ceur-ws.org/Vol-931/.The proceedings contain papers on the topic of awareness and reflection, in particular the technologies that may help researchers and other practicioners become aware of their context and reflect upon i
Understanding the meaning of awareness in Research Networks
No full textReinhardt, W., Mletzko, C., Sloep, P. B., & Drachsler, H. (2012). Understanding the meaning of awareness in Research Networks. In A. Moore, V. Pammer, L. Pannese, M. Prilla, K. Rajagopal, W. Reinhardt, Th. D. Ullman, & Ch. Voigt (Eds.), Proceedings of the 2nd Workshop on Awareness and Reflection in Technology Enhanced Learning. In conjunction with the 7th European Conference on Technology Enhanced Learning: 21st Century Learning for 21st Century Skills (ARTEL/EC-TEL 2012) (pp. 13-30). September, 18, 2012, Saarbrücken, Germany. Available online at http://ceur-ws.org/Vol-931/ . [Please see also http://hdl.handle.net/1820/4729]underpinning and description of a tool that helps researchers become aware of their research context and reflect upon i
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