47 research outputs found
FREE RADICALS PROMOTE IN VIVO A DIFFERENT INTRACELLULAR DECAY OF RABBIT RETICOLOCYTE AND ERYTHROCYTE GLICOLIT ENZYMES.
No full textFree radicals promote "in vitro" a different intracellular decay of rabbit reticulocyte and erythrocyte glycolytic enzymes
No full textIntemational Symposium on Red Blood CelI Agi
A 20-year experience with mitral valve repair with artificial chordae in 608 patients
No full textObjective: Mitral valve repair with artificial chordae for degenerative mitral regurgitation
is widely adopted. We evaluated long-term results of mitral repair with
expanded polytetrafluoroethylene sutures (GORE-TEX CV-5; W. L. Gore & Associates,
Inc, Flagstaff, Ariz).
Methods: Between November 1986 and November 2006, 608 consecutive patients
underwent mitral repair with artificial neochordae. Mean age was 55 6 11 years
(15–85 years); 433 (71.2%) were male. Valve disease was purely degenerative in
555 patients (91.3%). Prolapse of anterior, posterior, or both leaflets was present in
47 (7.7%), 308 (50.7%), and 253 (41.6%), respectively. Atrial fibrillation was associated
in 117 (19.2%). In 125 cases (20.5%), additional surgical procedures were performed.
Follow-up was complete at a median of 5.7 years (interquartile range 2.2–9.8
years, range 0–19.4 years).
Results: In-hospital mortality was less than 1% (6 deaths). Overall and cardiac late
mortalities were 6.6% and 3.9% (34 and 24 deaths). Kaplan–Meier survival at 15
years was 84% (95% confidence interval 75%–90%). Freedoms from endocarditis,
thromboembolic events, reoperation, and recurrent mitral regurgitation at 15 years
were 97% (95% confidence interval 93%–99%), 92% (87%–95%), 92% (88%–
95%), and 85% (78%–91%), respectively. Sinus rhythm was restored in 75% (33
patients) after surgical atrial fibrillation correction. Calcification of GORE-TEX
neochordae was never reported.
Conclusion: Mitral valve repair with GORE-TEX artificial chordae is effective, safe,
and associated with low operative mortality and low rates of valve-related complications
at long-term follow-up. Artificial chordae showed excellent biologic adaptation,
retaining flexibility and tension with time
Analysis of amino acids as DABS-derivatives with a sensitivity to the femtomole level using RP-HPLC narrow-bore column.
No full textPreparative purification of pig red blood cell hexokinase type III using a new efficient chromatographic support
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Phenotype characterization of the anti-inflammatory behavior of decidual endothelial cells
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