530 research outputs found
Novel Material and Processing Conditions for Coating Stents: Adhesion, Roughness and Tickness Evaluation
Coating process and early stage adhesion evaluation of poly(2-hydroxy-ethyl-methacrylate) hydrogel coating of 316L steel surface for stent applications
In this study, a spray-coating method has been set up with the aim to control the coating of poly(2-hydroxy-ethyl-methacrylate) (pHEMA), an hydrophilic polymeric hydrogel, onto the complex surface of a 316L steel stent for percutaneous coronary intervention (PCI). By varying process parameters, tuneable thicknesses, from 5 to 20 μm, have been obtained with uniform and homogeneous surface without crack or bridges. Surface characteristics of pHEMA coating onto metal surface have been investigated through FTIR-ATR, contact angle measurement, SEM, EDS and AFM. Moreover, results from Single-Lap-Joint and Pull-Off adhesion tests as well as calorimetric analysis of glass transition temperature suggested that pHEMA deposition is firmly adhered on metallic surface. The pHEMA coating evaluation of roughness, wettability together with its morphological and chemical stability after three cycles of expansion-crimping along with preliminary results after 6 months demonstrates the suitability of the coating for surgical implantation of sten
Progettazione e sviluppo di nuovi sistemi per il rilascio controllato di agenti antirestenosi da stent coronarici
New coating of 316L steel bare stent to increase its biocompatibility through controlled release of therapeutics
Stimulated Raman scattering in nanostructured materials
Nonlinear optics at nanoscale is an intriguing research field of great significance from both fundamental and applicative point of view.In this paper, the phenomena of stimulated Raman scattering in both nanostructured silica based materials and nanostructured silicon based materials are investigated and discussed
Tailoring nonlinear nanostructured materials for integrated sources based on stimulated raman scattering
In this paper, the possibility to obtain new materials with both large Raman gain coefficients and spectral bandwidth is investigated. In particular, silica-niobia based glasses have been characterized by Raman spectroscopy. Our silica-based glass system (K 2 O-Nb 2 O 5 -SiO 2 (KNS)) are obtained by a thermal treatment resulting in a nanocomposite material of easy and cheap production. Our glass composition have demonstrated both a strong Raman gain and a large bandwidth. These results can be related to nanostructured material domains
Femtosecond stimulated Raman spectroscopy and preliminary steps for nonlinear microscopy
In this paper, experimental set up details and the main experimental issues of femtosecond Stimulated Raman Spectroscopy implementation are reported. In addition, preliminary steps towards nonlinear microscopy in biological sample are described. First, the integration of femtosecond Stimulated Raman Spectroscopy in a laser scanning microscope and, then, label free imaging of polystyrene-beads are demonstrated
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