18 research outputs found
Preliminary study on combined pharmacological and laser treatment in optic pit serous maculopathy after literature review.
No full textCorneal haze in course of Fuchs' endothelial dystrophy.
No full textThis article describes the observations obtained with confocal microscopy (CM) on the corneal structure in course of corneal edema in a patient with Fuchs endothelial corneal dystrophy (FD). The patient was a 40 year old male, suffering from second stage FD, in course of corneal edema and bullous keratopathy. The tissue structure was analyzed with CM confoscan CS4 (Nidek Technologies(®), Birmingham, UK) using the 40x mode. The CM has shown the presence of gaps due to corneal edema and a diffuse stromal hyper reflectivity related to the alteration of the extracellular matrix. It has also showed the presence of binucleate cells, assimilable to keratocytes, in cytokinesis which presented a typical fusiform aspect with two highly reflective nuclei awaiting cell division. The total number of cells was much lower than that of healthy control subjects of similar age, sex and race. The CM in this case suggests a significantly lower number of cells, presumably keratocytes, compared to normal range, but mostly it shows the presence of cells undergoing cytokinesis, which witnesses the active processes of collagenogenesis and possible vasculogenesis that represent early stages of loss of the normal corneal transparency
Detection of myopic foveoschisis by means of hi-tech diagnostic exams.
No full textAim: Myopic foveoschisis (MF) is the splitting of the retinal
layers in the fovea, probably caused by the excessive elongation of the ocular globe in patients with high myopia (HM). The aim of the study was to evaluate the morphological
and functional characteristics of the retinal area affected
by MF.
Methods: Five eyes of 10 patients were diagnosed with MF by spectral domain optical coherence tomography (SD-OCT). Patients were examined using both a nineteen-line raster scan and a three-dimensional scan during the same visit. All subjects underwent monocular instrumental registration of the visual characteristics of macular areas such as macular thickness, retinal functionality and sensitivity values. The patients and control subjects underwent also multifocal electroretinography
(mfERG) and Microperimetry (MP-1) and the obtained results were compared to show the effects of pathologies of the inner and outer retinal layers. The statistic analysis with nonparametric tests for the examined variables, and in particular the Wilcoxon Signed Ranks test for paired data, was performed.
Results: The two tailed test yielded statistically significant values in the MF group for all three studied characteristics, OCT, mfERG and MP-1, in both the first and second ring. In the third area between 5° and 10° the alterations of the values proved to be statistically significant only for macular thickness
measured by OCT and amplitude of the P1 wave shown in the mfERG results.
Conclusions: The nineteen-line raster scan and the three-dimensional
scan mode of SD-OCT were useful for the detection
of the pathologies that accompany MF, also providing important informations before and after a possible vitreo-retinal
surgery. However these informations must be supported by objective and subjective functional tests just as mfERG and MP-1
Preliminary study on combined pharmacological and laser treatment in optic pit serous maculopathy after literature review.
No full textThe pit of the optic nerve head (ON) is a rare congenital defect that sometimes presents itself with a maculopathy of various neuroretinal layers for unknown reason. This study was focused, before and after pharmacological and parasurgical treatment, on the structural and functional visual assessment in a patient with optic pit maculopathy (OPM). In order to achieve this the latest generation of hi-tech diagnostic tests were used, such as Spectral-Domain Optical Coherence Tomography (SD-OCT), Visual Evoked Potentials (VEP), full-field Electroretinography (ERG), multifocal ERG (mfERG), Microperimetry (MP-1), Standard Automated Perimetry (SAP), Fluorescein Angiography (FA) and Indocyanine Green Angiography (ICG). The research was conducted through a review of past and recent literature
Oxidative stress in the closed-eyelid test: management of glaucoma
No full textBACKGROUND AND OBJECTIVES: To evaluate the role of antioxidant drugs in the tonometric increase that follows the closed eyelid test (CET), a predicitive test for glaucoma, after administration of antioxidant substances was observed. MATERIALS AND METHODS: 30 subjects of 54.57 +/- 5.62 years, 13 males and 17 females, were examined by measuring the ocular pressure after 1 hour from the CET, both in normal conditions and after the administration of antioxidants such as: vitamin A (50,000 IU/die), vitamin E (600 mg/die), and vitamin C (1000 mg/die).The increases in temperature of the iridocorneal angle and of the iris were also measured in the same conditions with an infrared Thermo-Precision tonometer (So la Electro-Optics, China) both before and after CET. RESULTS: The results showed increased pressure after CET and decreased pressure after the administration of each antioxidant substance, although vitamin A was found to be more effective and with statistically significant values compared to vitamins E and C. CONCLUSIONS: Considering the responses obtained after administration of antioxidant drugs, the ocular hypertension induced after CET could be a response to mixed stress, oxidative and thermic, with degenerative effects on the trabecular meshwork (TM). Besides, in light of these considerations the research results underline that the open angle glaucoma (OAG) should be considered a multifactorial degenerative disease
Le modificazione del microcircolo sublinguale nei pazienti trattati con chemioipertermia intraoperatoria: studio pilota
No full textStress hyperglycemia as a modifiable predictor of futile recanalization in patients undergoing mechanical thrombectomy for acute ischemic stroke
No full textIntroduction: Mechanical thrombectomy (MT) is the first line treatment in acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Approximately half of patients treated with MT does not have a favorable outcome 3 months after stroke. The aim of this study was to identify predictors of futile recanalization (FR) in patients with LVO treated with MT. Methods: A retrospective analysis of consecutive patients with acute ischemic stroke due to anterior circulation LVO who underwent MT. Patients with a TICI score of 2b or 3 were included. We distinguished two groups, FR and meaningful recanalization (MR), according to patients' disability three months after stroke (FR: mRS score > 2; MR: mRS score < 2). Results: We enrolled 238 patients (FR, n = 129, 54.2%; MR, n = 109, 45.8%). Age (OR 1.05, 95% CI 1.01–1.09, p = 0.012), female sex (OR 2.43, 95% CI 1.12–5.30, p = 0.025), stress hyperglycemia, as measured by the GAR index, (OR 1.17, 95% CI 1.06–1.29, p = 0.002), NIHSS at admission (OR 1.15, 95% CI 1.07–1.25, p = 0.001) and time from symptoms onset to MT (OR 1.01, 95% CI 1.00–1.01, p = 0.020) were independent predictors of FR. The AUC for the model combining age, female sex, GAR index, NIHSS at admission and time from symptoms onset to MT was 0.81 (95% CI 0.76–0.87; p < 0.001). The optimal GAR index cut-off score to predict FR was 17.9. Discussion: FR is common after MT. We recognized older age, female sex and baseline NIHSS as non-modifiable predictors of FR. On the other hand, time from symptoms onset to MT and stress hyperglycemia were modifiable pre- and post-MT factors, respectively. Any effort should be encouraged to reduce the impact of these modifiable predictors
Primer registro de Hypercompe indecisa (Lepidoptera: Noctuidae: Arctiinae) en perales y álamos en la Patagonia
No full textLa región del Alto Valle de Río Negro y Neuquén es la zona más importante de producción de frutas de pepita de la Argentina. La principal plaga de estos cultivos es Cydia pomonella L. (Lepidoptera: Tortricidae). Los cambios implementados en las estrategias de control, principalmente la generalización del uso de la Técnica de Confusión Sexual, han causado en los últimos años cambios en la biodiversidad en esos cultivos. Durante la temporada 2008/09, en un establecimiento frutícola de producción orgánica en Vista Alegre (Neuquén), fue detectada Hypercompe indecisa (Walker) (Lepidoptera: Noctuidae), produciendo graves daños en frutos y hojas de perales y sobre el follaje de Populus spp. Se cita por primera vez a H. indecisa para la Patagonia y el primer hallazgo de esta especie sobre Populus spp. y Pyrus communis L
Zelus renardii (Hemiptera: Reduviidae: Harpactorinae: Harpactorini): first record from Argentina
No full textSe documenta por primera vez a Zelus renardii Kolenati en la Argentina a partir de especímenes colectados en el norte de la Patagonia en el Alto Valle de Río Negro y Neuquén. Se detallan las características que permiten reconocer a la especie y se señala su potencialidad de expansión hacia otras regiones de Sudamérica
Biology of blepyrus clavicornis (compere) (hymenoptera: encyrtidae), a parasitoid of pseudococcus viburni (signoret) (hemiptera: pseudococcidae).
No full textMealybugs (Hemiptera: Pseudococcidae) are common pests in fruitproduction(Franco et al., 2009; Daane et al., 2012). The obscure mealybug Pseudococcus viburni (Signoret) is a cosmopolitan and polyphagous species found in 56 countries. It feeds on members of nearly 90 plant families and 240 genera (García et al., 2016), and is one of the main pest species of vineyards (Vitis spp., Vitaceae) in Brazil as well as other countries of the Americas (Correa et al., 2012; Daane et al., 2012; Pacheco da Silva et al., 2014). P. viburni also attacks other plants of economic importance, such as apples (Rosaceae) and pears (Rosaceae) (Ciampolini et al., 2002; Dapoto et al., 2011). It feeds on the leaves, trunks, cordons, canes, fruits and roots of host plants. Similarly to other mealybug species, P. viburni causes damage to leaves and grape clusters due to its copious secretion of honeydew, which provides a substrate for the development ∗ Corresponding author. E-mail: [email protected] (V. Pacheco da Silva). of sooty mold, responsible for losses in productivity, marketability and quality of grapes (Daane et al., 2012). Moreover, the species has been related to the transmission of Grapevine leafroll associated virus and Grapevine Trichovirus A and B, viruses that cause vineyard degeneration, and losses in the productivity and quality of clusters (Garau et al., 1995; Golino et al., 2002)
