202 research outputs found

    Prediction Method for the Surface Damage in Splined Couplings

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    The primary purpose of my PhD thesis was to develop design criteria and to verify procedures about fretting wear, that are applicable to crowned spline couplings of a power transmission system of the aeroengines. Fretting is a very complex phenomenon being influenced by many factors, the most important being the presence or absence of lubrication, the load distribution (contact pressure) and the sliding between the bodies. Therefore, the study of fretting needs a deep knowledge of these three main aspects. The first aspect of the problem was based on models and experimental tests considering specify specimens (crowned spline couplings) and imposed movements, so as to uniquely identify the working conditions (load and sliding), in order to facilitate the comparison between the experimental tests and the analytical models. The analytical models have been validated with numerical simulations and by comparison with experimental data, that have been obtained by means of a dedicated test bench that has been designed and built. Thanks to the test rig was possible to determinate the real contact pressure of two engaging teeth; in fact, it is one of the most important parameters affecting the fretting phenomenon, but it is very difficult to evaluate in a quantitative way, especially when considering components with complex geometries. The second phase of this thesis was the development of a predictive model for crowned splined couplings. This model is based on the Ruiz first parameter. The aim of my thesis is to demonstrate how this parameter may be correctly applied to a complex component as the crowned spline coupling, taking into account experimental and FEM validation

    One Perspective on Harriet Cuffaro: A Story of Engagement and Experience

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    The author presents her learning process in creating this essay, by highlighting some of Harriet Cuffaro\u27s many insights, which she offers within the context of an unfolding story. She also takes the liberty of weaving her story together with Cuffaro\u27s, interwoven with aspects of John Dewey’s philosophy

    Preparation of 1,6-di-deoxy-D-galacto and 1,6-di-deoxy-L-altro nojirimycin derivatives by aminocyclization of a 1,5-dicarbonyl derivative

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    Iminosugars are known glycosidase inhibitors which are the subject of drug development efforts against several diseases. The access to structurally-related families of iminosugars is of primary importance for running structure-activity relationship studies. In this work, the double reductive amination (aminocyclization) reaction of a dicarbonyl derivative of the L-arabino series, in turn obtained from lactose, is reported. Different ratios of 1,6-di-deoxy-D-galacto and 1,6-di-deoxy-L-altro nojirimycin derivatives were obtained depending on the amine employed in this transformation which provided an insight into the effects of their structure on the outcome of the reaction. Of particular interest were the results obtained when two enantiomeric amino acids (D-Phe-OMe and L-Phe-OMe) were used, which resulted in the inversion of the reaction stereoselectivity

    Adult complex regional pain syndrome type I: A narrative review

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    Complex regional pain syndrome type I (CRPS I) is a multifactorial painful disorder with a complex pathogenesis. Both peripheral and central mechanisms are involved. Acute CRPS I is considered to be an exaggerated inflammatory disorder; however, over time, because of altered function of the sympathetic nervous system and maladaptive neuroplasticity, CRPS I evolves into a neurological disorder. This review thoroughly describes the pathophysiological aspects of CRPS I and summarizes the potential therapeutic options. The mechanisms and targets of the treatment are different in the early and late stages of the disease. This current review builds on a previous review by this author group by deepening the role of the peripheral classic and neuronal inflammatory component in the acute stage of this painful disorder. Level of evidence: Not applicable

    sub art. 10 l. n. 392/1978

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    Commento all'art. 10 l. n. 392/197

    Le spese di registrazione del contratto di locazione (commento all'art. 8, l. 27.7.1978, n. 392)

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    Viene fornito un commento all'art. 8 della l. 392/1978, relativo al riparto delle spese di registrazione del contratto di locazion
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