1,556 research outputs found
Myosin light and heavy chains in rat gastrocnemius and diaphragm muscles after chronic denervation or reinnervation
No full textMyosin light and heavy chains in rat gastrocnemius and diaphragm muscles after chronic denervation or reinnervation.
Carraro U, Catani C, Dalla Libera L.
Exp Neurol. 1981 May;72(2):401-12. No abstract available.
PMID:
7238699
[PubMed - indexed for MEDLINE
Differential distribution of tropomyosin subunits in fast and slow rat muscles and its changes in long-term denervated hemidiaphragm
No full textDifferential distribution of tropomyosin subunits in fast and slow rat muscles and its change in long-term denervated hemidiaphragm.
Carraro U, Catani C, Dalla Libera L, Vascon M, Zanella G.
FEBS Lett. 1981 Jun 15;128(2):233-6. No abstract available.
PMID:
7262316
[PubMed - indexed for MEDLINE
Recent advances in the pathology of idiopathic thrombocytopenic purpura
No full textIdiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder in which, for reasons that remain unclear, platelet surface proteins become antigenic and stimulate the immune system to produce autoantibodies and cytotoxic T lymphocytes. This results in immune-induced platelet destruction and suppression of platelet production.1-6 What causes the loss of tolerance to one’s own platelets remains unclear and is likely to be a result of a number of different co-operating factors including genetics (polymorphism in selected genes) and environment events (virusand bacteria-associated ITP).3 Both acute and chronic forms of disease can be distinguished. In children acute ITP is often associated with a viral or bacterial infection and generally resolves spontaneously within 6 weeks. Approximately 20% of children with acute ITP progress to the chronic form. In contrast ITP in adults is generally chronic and often requires treatment.
Complete subcutaneous rupture of the patellar tendon: Epidemiological and treatment problems in athletes
No full textE. Verni, F. Catani, R. Beluzzi, G. Del Prete, L. Prosperi, and R. Buda: Complete subcutaneous rupture of the patellar tendon: epidemiological and treatment problems in athletes. J. Sports Traumatol. rel. res. 19: 38, 1997. An account is given of 14 cases of patellar tendon rupture observed in 10 years with a minimum follow-up of 18 months. All athletes were treated with the same surgical technique. In addition to providing temporary protection for the tendon suture, cerclage is a sound means of securing the correct position of the patella. The results show that resumption of sport is a more selective criterion than modem clinical and instrumental investigations. The common epidemiological denominator was eccentric pliometric power training. In the absence of controlled scientific data concerning this form of functional overuse, careful selection and periodic monitoring is required of athletes whose explosive force is to be increased through previous stretching of a muscle
Kindesmissbrauch und Reviktimisierung
No full textLanger L, Catani C. Kindesmissbrauch und Reviktimisierung. Zeitschrift für Klinische Psychologie und Psychotherapie. 2017;45(4):279-289
Human megakaryocyte biology and pathophysiology
No full textMegakaryocyte developmentin vitro requires the presence of at least two overlapping regulatory activities: a colony stimulating activity which promotes cellular proliferation and limited maturation and a second co-regulator
which directs maturational development. Since the responding meg cell populations represent a con-
tinuous spectrum of differentiating cell phenotypes, factor responsivenessclearly overlaps. These two rather
distinct processes as well as their complex regulation will be discussed in the first section of this review dealing
with the biology of megakaryocytopoiesis .
In the second part of this review we will consider a number of megakaryocytic disorders, comprising reactive and neoplastic diseases, which have been primarily characterized in the past by bone marrow histopathology
Macrophages regulate proliferation and differentiation of satellite cells
No full textBiochem Biophys Res Commun. 1994 Aug 15;202(3):1688-96.
Macrophages regulate proliferation and differentiation of satellite cells.
Cantini M, Massimino ML, Bruson A, Catani C, Dalla Libera L, Carraro U.
Source
Department of Biomedical Sciences, University of Padova, Italy.
Abstract
We used an in vitro model to investigate whether macrophages stimulate satellite cells proliferation. Satellite cells were obtained by tryptic digestion of adult muscle. Macrophages were obtained from peritoneal cavity by wash after injection of thioglycolate broth. Macrophages and satellite cells cocultures showed an increased number of differentiated myotubes as compared to control cultures. Moreover, in conditions of myoblast colony growth, the addition of macrophage-conditioned medium resulted in a greater number of muscle cell colonies, which are richer in large and differentiated myotubes. The experiments with macrophage-conditioned media suggest that the increased muscle cell proliferation and differentiation is mediated by soluble factor(s) released by macrophages. These results demonstrate that besides their scavenger role macrophages play a pivotal role in myoblast proliferation during muscle regeneration.
PMID:
8060358
[PubMed - indexed for MEDLINE
Archaeological and historical notes on the Castellum Tariona in the Roman Era
No full textAutor donosi ispravak dosadašnjeg čitanja rimskoga
terminacijskog natpisa iz Bljušćevice kod sela Rastovca u
Trogirskoj zagori koji je u vrijeme Publija Kornelija Dolabele
uklesan u kamen živac. Također donosi novi nalaz cipusa iz zaselka
Bašelovici u Grebaštici kod Šibenika. Na njemu se spominje
Salto(ru)m F(inis) / Tariot(arum), a oznacava zapadnu granicu
tariotskog pašnjaka.The author provides a correction to the previous reading of the
Roman boundary inscription from Bljušćevica near the village of
Rastovac in the elevated hinterland of Trogir which was engraved
in solid rock during the consulship of Publius Cornelius Dolabella.
He also presents a new discovery of a cippus from the hamlet
of Bašelovici in Grebaštica near Šibenik. The inscription reads
Salto(ru)m F(inis) / Tariot(arum), designating the western boundary
of the Tariote pastures
Hypercoagulability during l‐asparaginase treatment: the effect of antithrombin III supplementation in vivo
No full textTo evaluate the occurrence of hypercoagulability during treatment with l‐asparaginase (l‐ase), thrombin‐antithrombin complex (TAT) and d‐dimer levels in plasma were serially measured in 15 consecutive adult patients with acute lymphoblastic leukaemia or lymphoblastic lymphoma who had recently completed a chemotherapy cycle with cytosine arabinoside and methotrexate. The first eight patients (group A) received i.v. l‐ase alone (20000 U/m2 on alternate days over 10 d); the last seven patients (group B) received, in addition to l‐ase, bolus injection of antithrombin concentrate (2000 U) on alternate days for a total of six administrations, beginning with the second l‐ase infusion. Increased levels of TAT (P<0·05) and d‐dimer (P<0·01) were observed prior to l‐ase, possibly related to inflammation and cytolysis secondary to previous chemotherapy. In patients treated with l‐ase alone, further elevation of TAT (P<0·05) and persistence of increased d‐dimer were observed, associated with marked reduction of the anticoagulant activities of protein C, protein S and antithrombin III. At variance, in patients receiving antithrombin III supplementation there was no increase of TAT and a normalization of d‐dimer levels occurred during l‐ase treatment. In these patients, mean plasma antithrombin III activity was maintained at levels higher than 70% of normal throughout the treatment. The rate of decline of fibrinogen, factor IX, protein C and protein S was unaffected by antithrombin III supplementation, indicating that hypercoagulability has little if any relevance for the reduction of coagulation factors and inhibitors induced by l‐ase treatment. The usefulness of antithrombin III concentrates in preventing thromboembolic complications in patients submitted to l‐ase treatment remains to be determined. Copyright © 1990, Wiley Blackwell. All rights reserve
Traffic crash pattern modification as a result of a 30 km/h zone implementation. A case study in Turin (Italy)
No full textThe strategy of 30 km/h zones, referred to in the international context as "traffic calming" measures, serves to safeguard pedestrians, cyclists and motorcyclists, collectively referred to as “vulnerable road users” (VRU). Its main function is to compel drivers to observe a maximum speed limit of 30 km/h. However, urban infrastructure transformations modify traffic collision patterns and the involvement of road users, with a spatial temporal redistribution of events. This work seeks to study the effects on collision distribution resulting from the introduction of a 30 km/h zone to the Mirafiori Nord area in the city of Turin in late 2008. Collision frequencies, based on data provided by the Italian National Institute of Statistics (ISTAT), were evaluated over the period 2006-2016. Road traffic collisions involving both VRU and motorized users (“noVRU”) were taken into account. Decreases in collision frequency were found for noVRU related crashes, while the VRU crash rate remained essentially unchanged with only minor fluctuations consistent with the regression to the mean phenomenon. The countermeasures, which sought to protect VRU, were however very effective for noVRU. As the effects of each structural modification spill over into neighboring areas, the analysis of collision frequency was extended to a study area greater than the one in which the 30 km/h zone was realized. In fact, due to the migration of events, the reduction in the collision frequency in the speed restricted zone was accompanied by an increase in the
same frequency in the immediate surrounding area
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