245 research outputs found
An integrated biomarker approach for assessing exposure and effects of endocrine disruptors and other contaminants in killifish (Fundulus heteroclitus) from the New York-New Jersey harbor estuary:
No full textA multi-tiered approach was used to evaluate killifish (Fundulus heteroclitus) health by examining a suite of biomarkers in killifish inhabiting the heavily industrialized Newark Bay and a reference population in Tuckerton, NJ. The general hypothesis of this study was that Newark Bay killifish would exhibit biomarker responses indicative of impaired health when compared to a reference population from Tuckerton, NJ. The biomarkers investigated included classical endpoints (histopathology, morphometrics, gonad maturation), hepatic mRNA expression (CYP1A, metallothionein, vitellogenin I), gonadal aromatase mRNA expression, hepatic protein levels (CYP1A and vitellogenin I) and chemical exposure analyses (bile PAHs). Newark Bay fish had significantly higher levels of bile PAHs compared to reference fish. Females had significantly higher concentrations of naphthalene, pyrene and benzo[a]pyrene (3, 6 and 4 fold higher, respectively, p<0.05). Males had significantly higher concentrations of pyrene (7-fold higher, p<0.05), and higher concentrations of naphthalene (4-fold higher, p=0.06) and benzo[a]pyrene (9-fold higher, p=0.07). Histological lesions of the liver and pancreas in Newark Bay fish were similar to reference fish. Newark Bay fish had significantly higher expression of hepatic CYP1A for both males and females (7 and 3 fold higher, respectively, p<0.05) and CYP1A protein levels for both males and females (5 and 8 fold higher, p<0.05). Endocrine disruption in male gonads is demonstrated by a decreased gonad weight, altered testis development and upregulated aromatase expression (3-fold, p<0.05), which indicates exposure to endocrine active compounds. Efforts to strip spawn Newark Bay females produced few viable eggs, while at the same time Tuckerton females produced large numbers of viable eggs. There was a significant increase in the percent of pre-vitellogenic follicles (43% at Tuckerton, 64% at Newark Bay) and a significantly decreased percent of follicles at the mid-vitellogenic and mature stages (25% at Tuckerton, 3% at Newark Bay) in Newark Bay females (p<0.05). Vitellogenin mRNA and protein (egg yolk-protein) was significantly decreased in Newark Bay females (6-fold lower mRNA, 27-fold lower protein, p<0.05) while gonadal aromatase (produces 17β-estradiol) was significantly increased (210-fold higher, p<0.05). Killifish in the NY-NJ Harbor Estuary are exposed to high amounts of PAHs and aryl hydrocarbon agonists and their reproductive health is impaired. Impaired reproductive health is possibly due to disruption of steroid signaling by aryl hydrocarbon receptor-estrogen receptor crosstalk leading to decreased vitellogenin production.M.S.Includes bibliographical references (p. 91-100)by Sean M. Buge
PENGGUNAAN MEDIA VISUAL (GAMBAR) TERHADAP PRESTASI BELAJAR MURID PADA MATA PELAJARAN PENDIDIKAN AGAMA ISLAM (PAI) DI SEKOLAH DASAR (SD) NEGERI BUGEL I KECAMATAN PATROL KABUPATEN INDRAMAYU
No full textA L F I A H, Ciamis- 20 April 1973 :“PENGGUNAAN MEDIA VISUAL
(GAMBAR) TERHADAP PRESTASI BELAJAR MURID PADA MATA
PELAJARAN PENDIDIKAN AGAMA ISLAM (PAI) DI SEKOLAH DASAR (
SD ) NEGERI BUGEL I KECAMATAN PATROL KABUPATEN
INDRAMAYU”.
Penulis dalam pendekatan yang di gunakan adalah melalui pendekatan empirik yaitu
suatu pendekatan yang digunakan untuk menemukan fakta yang sebenarnya yang
terjadi, untuk mendapatkan pembelajaran Pendidikan Agama Islam yang mengampu
di lokasi penelitian yaitu Sekolah Dasar (SD) Negeri Bugel I Kecamatan Patrol
kabupaten Indramayu.
Masalah pengajaran pendidikan agama di sekolah sudah saatnya dipikirkan,
dianalisis, dan diindetifikasikan masalahnya secara lebih serius. Karena masalah
pengajaran pendidikan agama di sekolah selain memiliki masalah yang tidak sedikit,
maka harus ada penambahan alat bantu yaitu dengan :Penggunaan Media Visual
(Gambar ) Terhadap Prestasi Belajar Pendidikan (PAI) suapa ada korelasi anak
didik terhadap daya serap dan daya nalar sebagai fisikomotorik untuk
menunjang pada Kegiatan Belajar Mengajar (KBM).
Pengumpulan data dilakukan melalui tehnik penyebaran angket , studi
kepustakaan dan dokumentasi. Tehnik analisis data dilakukan dengan cara
menganalilisis data kuantitaif yaitu dengan menemukan fakta berupa angka-angka
yang dipaparkan terhadap data kuantitatif setelah dilakukan tabulasi dan menentukan
prosentasi keberhasilan peserta didik.
Berdasarkan hasil penelitian dapat disimpulkan bahwa respon siswa tentanghasil dari
interprestasi kualitatif nilai rxyyang memperoleh nilai sebesar 0,73 terletek diantara
nilai 0,70 – 0,90 berada dalam interprestasi korelasi yang tinggi. Jadi kesimpulannya
adalah : Terhadap hubungan yang fositif dan signifikan adalah sebesar 0,73 terhadap
Penggunaan Media Visual (Gambar) Terhadap Prestasi Belajar Murid Pada
Mata Pelajaran Pendidikan Agama Islam (PAI) di Sekolah Dasar (SD) Negeri Bugel I
Kecamatan Patrol Kabupaten Indramayu
Contaminant effects on vitellogenesis and oogenesis in zebrafish (danio rerio) and killifish (fundulus heteroclitus) from the chemically impacted Newark Bay, NJ
No full textVitellogenins are large glycolipoprotein precursors to yolk–proteins that act as vital biomolecules and growth substrate in developing oocytes of teleosts and are synthesized exclusively in the liver. The studies in this Dissertation tested the general hypothesis that aryl hydrocarbon receptor agonist contaminants in Newark Bay, NJ down–regulate hepatic vitellogenin synthesis, resulting in inhibition of oogenesis and reproductive dysfunction. This hypothesis was examined using a variety of studies with a field population of killifish (Fundulus heteroclitus) from the contaminated Newark Bay and relatively clean Tuckerton, NJ, and using lab studies with zebrafish (Danio rerio) as a model teleost. In killifish native to Newark Bay, inhibition of oocyte yolk–development resulted in decreased egg production, decreased embryo mass and reduced yolk–volume. The cause of these effects was shown to be the down–regulation of vitellogenesis in the liver. Decreased vitellogenin expression during spawning was demonstrated to be due to deficient levels of circulating 17β–estradiol, and a decreased sensitivity of the vitellogenin pathway to induction (protein and mRNA levels) by physiological doses of 17β–estradiol. In the Newark Bay population, vitellogenin expression was inversely correlated with CYP1A, a biomarker for aryl hydrocarbon receptor 2 (AhR2) activity. I therefore propose that the down–regulation of the vitellogenin pathway is phenotypic of aryl hydrocarbon receptor mediated cross–talk inhibition of the estrogen receptor (ER). The role of AhR2 in mediating AhR–ER cross–talk inhibition of vitellogenin was examined using the zebrafish as a model teleost. The potent AhR agonists 2,3,7,8–tetrachlorodibenzo–p–dioxin and 1,2,3,7,8–pentachlorodibenzo–p–dioxin were found to inhibit the induction of vitellogenins 1, 2 and 3 by 17α–ethynylestradiol in zebrafish. Transient knock–down of AhR2 levels showed that the AhR2 mediates inhibition of vitellogenesis by 2,3,7,8–tetrachlorodibenzo–p–dioxin, demonstrating that AhR2 activation plays a role in AhR–ER cross–talk. Taken together, these studies demonstrated that the contaminant induced down–regulation of vitellogenesis in the liver can cause reproductive dysfunction in the ovary and that the mechanism for these effects is mediated through AhR2–ER signaling pathways.Ph. D.Includes bibliographical referencesby Sean Michael Buge
Pengaruh Macam Pupuk Kandang Terhadap Pertumbuhan dan Hasil Tiga Kultivar Kacang Hijau (Vigna radiata L. Wilczek) di Lahan Pasir Pantai Bugel, Kulon Progo
No full textINTISARI Lahan pasir pantai yang terdapat di daerah Bugel merupakan gumuk-gumuk pasir. Karakteristik lahan di gumuk pasir wilayah ini adalah tanah bertekstur pasir, struktur berbutir tunggal, daya simpan lengasnya rendah, status kesuburannya rendah, evaporasi tinggi, dan tiupan angin laut kencang. Penambahan pupuk kandang diyakini dapat memperbaiki sifat fisika, kimia dan biologi tanah, oleh karena itu, suatu kajian dilaksanakan untuk mengetahui pengaruh pemberian pupuk kandang sapi, kambing, dan ayam terhadap pertumbuhan dan hasil tanaman tiga kultivar kacang hijau (Vigna radiata L. Wilczek). Penelitian dilakukan di lahan pasir Pantai Bugel, Yogyakarta pada bulan September–Desember 2013. Penelitian ini dirancang dengan menggunakan metode Rancangan Acak Kelompok Lengkap (RAKL) dengan dua faktor dengan faktor pertama yaitu jenis pupuk kandang (tanpa pupuk, pupuk kandang sapi, ayam dan kambing) dan faktor kedua yaitu tiga kultivar (Vima-1, Murai, Kenari). Data yang diperoleh dianalisis dengan menggunakan analisis varian (Anova) dengan taraf 5 %. Apabila hasil analisis varian terdapat beda nyata maka dilanjutkan dengan Duncan Multiple Range Test (DMRT) dengan tingkat kepercayaan 5%. Untuk mengetahui keterkaitan antar parameter dalam penelitian ini digunakan analisis korelasi. Hasil penelitian menunjukkan penambahan pupuk kandang kambing mampu meningkatkan pertumbuhan vegetatif tanaman kacang hijau. Perlakuan pemberian pupuk kandang ayam menghasilkan berat biji per hektar lebih tinggi yaitu 1,84 ton per hektar dibandingkan dengan pupuk kandang kambing, pupuk kandang sapi maupun tanpa pemupukan. Kacang hijau kultivar Kenari mampu memproduksi berat biji per hektar paling tinggi dengan berat 1,83 ton per hektar dibandingkan kultivar Vima-1 maupun Murai.Kata kunci : kacang hijau, pupuk kandang, pasir panta
PENGARUH MACAM PUPUK KANDANG TERHADAP PERTUMBUHAN DAN HASIL TIGA KULTIVAR KACANG HIJAU (Vigna radiata L. Wilczek) DI LAHAN PASIR PANTAI BUGEL, KULON PROGO
No full textSome coastel region at Bugel are as sand-dunes. Characteristics of the dunes are sand-textured soils, single grained structure, water holding capacity and the status of low fertility, high evaporation, and the strong sea wind. The addition of manure is believed to improve the nature of physics, chemistry and biology of the soil, therefore, a study used carried out to determine the effect of manure of cattle, goats, and chickens on growth and yield of three cultivars of mung bean (Vigna radiata L. Wilczek). The study was conducted at coastel Bugel, Yogyakarta in September-December 2013. The field experiment was designed as Complete Randomized Block Design (RCBD) with two factors. The first factor is the type of manure and the second factor as kind varieties (Vima-1, Murai, Kenari). The observed data at analyzed using analysis of variance (ANOVA) with the level of credibility at 5 %. If the results of the analysis of variance are significantly different formatting as between than followed by Duncan's Multiple Range Test (DMRT) at 5% level of confidence. To determine the relationship between parameters used in this study followed the correlation analysis. The results showed that the addition of goat manure could increase the vegetative growth of green bean plants. Chicken manure treatment resulted in seed weight per hectare higher at 1,84 tons per hectare compared to goat manure, cow manure and control. Murai cultivars have better vegetative growth than of most cultivars Vima-1 and Kenari. Kenari green bean cultivars capable of producing weight seeds per acre with the highest weight at 1,83 tons per hectare compared to cultivars Vima-1 and Murai
‘L´Espanyol conquereix el Brasil’, L´Expansió de l´Espanyol a l´Estranger: Articles de la Premsa Espanyola
No full textAn evaluation study: an examination of the impact of noninvasive interventions by social workers on successful pain management among hospice clients
No full textThis study evaluated the effectiveness of using noninvasive intervention strategies, as administered by a social work practitioner, to enhance successful pain management among the hospice client population. The study was based on the assumption that successful pain management among hospice clients is dependent upon noninvasive social work interventions for three reasons: a) not all sensations of pain can be successfully addressed by invasive medical, pharmaceutical interventions; b) noninvasive interventions of social workers are 'self- empowering,' reinforcing the client's full control of self, environment, treatment, and death; and c) theory and practice methods for noninvasive strategies are grounded in a general systems theory paradigm. A 'B,' intervention only design was used. The questionnaire was created by the researcher and administered by four interviewers to a select group of hospice clients in the Atlanta Metropolitan area. Descriptive analysis was used to see if successful pain management was improved by the intervention of noninvasive strategies. The researcher found that noninvasive interventions of social workers have a moderate impact on successful pain management among the hospice client population. The conclusions drawn from the findings suggest that the approach taken by social workers, to give palliative care by addressing the psychosocial concerns of the client, maybe a valuable component of the interdisciplinary hospice team and clearly warrants more research
Pengaruh Mulsa Organik Terhadap Pertumbuhan dan Hasil Tiga Varietas Kacang Hijau (Vigna radiata L. Wilczek) di Lahan Pasir Pantai Bugel, Kulon Progo
No full textPenelitian ini bertujuan untuk mempelajari respon tiga varietas kacang hijau terhadap agroekosistem lahan pasir, serta pengaruh pemberian mulsa organik (jerami dan sekam) terhadap pertumbuhan dan hasil dari tiga varietas kacang hijau (Vigna radiata L. Wilczek) yang ditanam di lahan pasir pantai. Penelitian ini dilakukan di daerah Bugel, Kecamatan Panjatan, Kabupaten Kulon Progo, Yogyakarta. Penelitian menggunakan Rancangan Acak Kelompok Lengkap (RAKL) faktorial, dengan dua faktor yakni varietas kacang hijau, terdiri dari Vima-1, Murai, dan Lokal Wonosari, dan mulsa yang terdiri dari tanpa mulsa, mulsa jerami, dan mulsa sekam dengan dosis masing-masing 5 ton/ha. Hasil penelitian menunjukkan varietas Vima-1 dan Murai memiliki respons yang lebih baik dibanding varietas Lokal Wonosari pada penanaman di lahan pasir. Kacang hijau Vima-1 dan Murai mampu merespon penggunaan mulsa organik di lahan pasir pantai, dengan selisih hasil masing-masing 0,51 ton/ha dan 0,45 ton/ha dibanding tanpa mulsa. Kacang hijau Lokal Wonosari kurang merespon penggunaan mulsa organik, dengan selisih hasil sebesar 0,12 ton/ha dibanding tanpa mulsa. Mulsa organik merupakan faktor pendukung pertumbuhan dan hasil kacang hijau. Mulsa jerami meningkatkan pertumbuhan dan hasil tanaman kacang hijau sebesar 31,25% dengan hasil 2,7 ton/ha, diikuti mulsa sekam sebesar 6,25% dengan hasil 1,7 ton/ha. Hasil kacang hijau Vima-1 pada mulsa jerami sebesar 2,4 ton/ha yang memberikan keuntungan sebanyak Rp. 10.677.500,-
Optimization Management for Chili (Capsicum annum L.) Production in Agroforestry System with Coconut (Cocos Nucifera L.) on Local Protected Coastline Areas
No full textBugel coastline areas have the potential for horticulture commodities development. This study's objectives were mapping protected Bugel coastline areas, land evaluation, and yield response of chili in an agroforestry system with coconut trees on Bugel coastline areas. The research was conducted during April-July, 2015, in Bugel coastline areas, Panjatan District, Kulonprogo Regency, Special Province of Yogyakarta. The first stage was the literature study and field mapping by BING satellite imagery. The second method was an actual and potential land evaluation using the FAO version, Sys criteria, and Sys limitation. The third method was using a randomized complete block design (RCBD) with three blocks as replications. The results showed that a local protected coastline area allowed for the agriculture and forestry crops is >200 meters from the furthest tide point. The actual and potential land evaluation in all agroforestry phases were not suitable and marginally suitable. The initial phase showed the highest fresh fruit weight by 100.30 grams/plant, compared with the intermediate and advanced phases by 88.13 grams/plant 71.54 grams/plant
An die Partei der Nichtwähler! ... Auf zur Wahl; Wählt Zentrum
No full textPoster shows a man blowing a bugel and holding a large mallet while surrounded by flames. Text addresses non-participating voters in Düsseldorf, stating that by not voting they are prolonging the suffering and delaying the return of order. It tells people to get to the election center and vote.Title from item
- …
