210 research outputs found
Supplemental material for Field testing the diagnostic criteria of cluster headache in the third edition of the International Classification of Headache Disorders: A cross-sectional multicentre study
No full textSupplemental Material for Field testing the diagnostic criteria of cluster headache in the third edition of the International Classification of Headache Disorders: A cross-sectional multicentre study by Heui-Soo Moon, Soo-Jin Cho, Byung-Kun Kim, Mi Ji Lee, Pil-Wook Chung, Jong-Hee Sohn, Soo-Kyoung Kim, Yun-Ju Choi, Tae-Jin Song, Jae-Moon Kim, Jeong Wook Park, Kwang-Yeol Park, Jae-Myun Chung, Jin-Young Ahn, Byung-Su Kim, Kyungmi Oh, Kwang-Soo Lee, Chin-Sang Chung and Min Kyung Chu in Cephalalgia</p
Application of time reversal guided waves to field bridge testing for baseline free damage diagnosis
No full textThis research is partially supported by Pennsylvania Infrastructure Technology Alliance (PITA) Program and Pennsylvania Department of Transportation (PennDOT). The first author would like to acknowledge the graduate fellowship program from Samsung Lee Kun Hee Scholarship Foundation in Seoul, Korea. The authors would like to thank Paul Majoris and James Johnson for granting access to the Buffalo Creek Bridge site. The authors also would like to thank Profs. David W. Greve and Irving J. Oppenheim for providing invaluable comments and making the scaled girder specimen available for our study
(A) study on growth changes of maxilla and mandible and position changes of first permanent molars of growing children
No full text치의학과/석사[한글]
성장기 아동을 대상으로 교정치료시 상하악골의 성장변화와 상하악 제 1대구치의 맹출 방향을 규명함으로서 부정교합 환자의 진단 및 치료계획 수립에 도움을 주기 위하여 저자는 남자 43명, 여자 39명의 6세부터 11세까지 촬영한 두부방사선 규격사진을 연구하여 다
음과 같은 결론을 얻었다.
1. TM-ANS, Mandibular plane을 중첩시켜 얻은 상하악 제 1대구치의 맹출방향은 개인차가 심하였다.
2. 상악 제 1대구치의 수평, 수직변화량은 상관관계가 없으며 하악 제 1대구치의 수평, 수직 변화량은 순상관관계를 보였다.
3. 하악 제 1대구치는 상악 제 1대구치보다 맹출하면서 전방이동량이 유의성있는 큰 값을 보였다.
4. 상하악골의 연령증가에 따른 변화량은 일정하지 않았다.
5. 하안면고경의 변화량은 비교적 일정하였다.
6. N-S-6은 7세 이후에 변화가 없었다.
A STUDY ON GROWTH CHANGES OF MAXILLA AND MANDIBLE AND POSITION CHANGES OF FIRST
PERMANENT MOLARS OF GROWING CHILDREN
Dae Hee Cho
Dept. of Dental Science, Graduate School, Yonsei University
(Directed by Prof. Byung Hwa Sohn, D.D.S., M.S.D., Ph.D.)
The purpose of this study was to investigate the growth changes of maxilla and
mandible and position changes of first permanent molars of growing children.
The author analyzed the data using cephalometric roentgenogram of 43 boys and 39
girls age of 6 to 11 with normal occlusion.
The obtained results were as follows
1. The eruption path of maxillary and mandibular first permanent molar
superimposed on TMANS and mandibular plane shows individual variation.
2. There was no correlation between horizontal and vertical changes of maxillary
first permanent molar, but positive correlation in mandibular first permanent
molar.
3. As the eruption, the forward changes of mandibular first permanent molar was
significantly greater than that of maxillary first permanent molar.
4. As the ages were increased, there were irregular growth changes of maxilla and
mandible.
5. Growth changes of lower anterior facial height was relatively stable
6. N-S-6 was stable after age7.
[영문]
The purpose of this study was to investigate the growth changes of maxilla and mandible and position changes of first permanent molars of growing children.
The author analyzed the data using cephalometric roentgenogram of 43 boys and 39 girls age of 6 to 11 with normal occlusion.
The obtained results were as follows
1. The eruption path of maxillary and mandibular first permanent molar superimposed on TMANS and mandibular plane shows individual variation.
2. There was no correlation between horizontal and vertical changes of maxillary first permanent molar, but positive correlation in mandibular first permanent molar.
3. As the eruption, the forward changes of mandibular first permanent molar was significantly greater than that of maxillary first permanent molar.
4. As the ages were increased, there were irregular growth changes of maxilla and mandible.
5. Growth changes of lower anterior facial height was relatively stable
6. N-S-6 was stable after age7.restrictio
Patient-Centeredness during In-Depth Consultation in the Outpatient Clinic of a Tertiary Hospital in Korea: Paradigm Shift from Disease to Patient
No full textBackground: Patient-centered care (PCC) and integrative care approach are widely advocated. However, their implementation usually requires an extended consultation time. Despite significant advances in medical diagnosis and treatment, no studies have examined consultation time and patient centeredness in Korea. Methods: We conducted a "15-Minute Consultation" for first-time patients in outpatient clinics of 13 departments. A control group was selected from the same physicians' first-time patients, adjusting for age and gender. A total of 275 patients were selected for receiving in-depth consultation and 141 control patients were selected for regular consultation. Data were collected from patients using a questionnaire comprising a patient-centeredness scale and items on potential predictors such as socio-demographic and clinical factors. We also investigated the participating physician's professionalism. Results: As compared to the control group, the in-depth consultation group scored higher on 5 variables associated with PCC, including (patients' perception of) medical professionals, wait and consultation times, treatment, patient advocacy, and patient satisfaction. While 92.4% of patients in the in-depth consultation group reported that the consultation time was sufficient, only 69.0% of those in the control group reported the same (P< 0.01). In the in-depth consultation group, scores on satisfaction level were the highest for the department of internal medicine, followed by departments of surgery and pediatrics. Participating physicians' improved satisfaction following the intervention proved that in-depth consultation facilitated building a rapport with patients. Conclusion: This study illustrated that the provision of sufficiently long consultation for serious and rare diseases could improve PCC and physicians' professionalism. Health authorities should reshuffle the healthcare delivery system and provide sufficient consultation time to ensure PCC and medical professionalism.ope
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The Effect of Repeated Testing on the Pattern and the Accuracy of Judgment of Learning
No full textEffects of cryogenic temperature on tensile and impact properties in a medium-entropy VCoNi alloy
No full textMulti-principal element alloys usually exhibit outstanding strength and toughness at cryogenic temperatures, especially in CrMnFeCoNi and CrCoNi alloys. These remarkable cryogenic properties are attributed to the occurrence of deformation twins, and it is envisaged that a reduced stacking fault energy (SFE) transforms the deformation mechanisms into advantageous properties at cryogenic temperatures. A recently reported high-strength VCoNi alloy is expected to exhibit further notable cryogenic properties. However, no attempt has been made to investigate the cryogenic properties in detail as well as the underlying deformation mechanisms. Here, the effects of cryogenic temperature on the tensile and impact properties are investigated, and the underlying mechanisms determining those properties are revealed in terms of the temperature dependence of the yield strength and deformation mechanism. Both the strength and ductility were enhanced at 77 K compared to 298 K, while the Charpy impact toughness gradually decreased with temperature. The planar dislocation glides remained unchanged at 77 K in contrast to the CrMnFeCoNi and CrCoNi alloys resulting in a relatively constant and slightly increasing SFE as the temperature decreased, which is confirmed via ab initio simulations. However, the deformation localization near the grain boundaries at 298 K changed into a homogeneous distribution throughout the whole grains at 77 K, leading to a highly sustained strain hardening rate. The reduced impact toughness is directly related to the decreased plastic zone size, which is due to the reduced dislocation width and significant temperature dependence of the yield strength.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Team Marcel Sluite
The Relationship between Prognostic Factors and the Expression Pattern of Fascin and E-cadherin in Renal Cell Carcinoma
No full textOptical imaging of absorption and distribution of RITC-SiO2 nanoparticles after oral administration
No full textChang-Moon Lee,1 Tai Kyoung Lee,2–5 Dae-Ik Kim,1,6 Yu-Ri Kim,7 Meyoung-Kon Kim,7 Hwan-Jeong Jeong,2–5 Myung-Hee Sohn,2–5 Seok Tae Lim2–5 1Department of Biomedical Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 2Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 3Cyclotron Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 4Biomedical Research Institute, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 5Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 6School of Electrical, Electronic Communication, and Computer Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 7Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seounbuk-Gu, Seoul, Republic of Korea Purpose: In this study, we investigated the absorption and distribution of rhodamine B isothiocyanate (RITC)-incorporated silica oxide nanoparticles(SiNPs) (RITC-SiNPs) after oral exposure, by conducting optical imaging, with a focus on tracking the movement of RITC-SiNPs of different particle size and surface charge. Methods: RITC-SiNPs (20 or 100 nm; positively or negatively charged) were used to avoid the dissociation of a fluorescent dye from nanoparticles via spontaneous or enzyme-catalyzed reactions in vivo. The changes in the nanoparticle sizes and shapes were investigated in an HCl solution for 6 hours. RITC-SiNPs were orally administered to healthy nude mice at a dose of 100 mg/kg. Optical imaging studies were performed at 2, 4, and 6 hours after oral administration. The mice were sacrificed at 2, 4, 6, and 10 hours post-administration, and ex vivo imaging studies were performed. Results: The RITC-SiNPs were stable in the HCl solution for 6 hours, without dissociation of RITC from the nanoparticles and without changes in size and shape. RITC-SiNPs flowed into the small intestine from the stomach and gradually moved along the gut during the experiment. In the ex vivo imaging studies, optical signals were observed mostly in the lungs, liver, pancreas, and kidneys. The orally administered RITC-SiNPs, which were absorbed in the systemic circulation, were eliminated from the body into the urine. The 20 nm RITC-SiNPs showed higher uptake in the lungs than the 100 nm RITC-SiNPs. The distribution of the 100 nm RITC-SiNPs in the liver was higher than that of the 20 nm RITC-SiNPs, but the differences in the surface charge behavior were imperceptible. Conclusion: We demonstrated that the movement of RITC-SiNPs after oral exposure could be traced by optical imaging. Optical imaging has the potential to provide valuable information that will help in understanding the behavior of SiNPs in the body following exposure. Keywords: silica nanoparticles, oral exposure, rhodamine B isothiocyanate, RITC-SiN
Changes in Stroke Patients' Health-Seeking Behavior by COVID-19 Epidemic Regions: Data from the Korean Stroke Registry
No full text© 2021 The Author(s) Published by S. Karger AG, Basel.Introduction: The coronavirus disease 2019 (COVID-19) pandemic has led to changes in stroke patients' healthcare use. This study evaluated changes in Korean stroke patients' health-seeking behaviors and stroke care services using data from the Korean Stroke Registry (KSR). Methods: We reviewed data from patients with acute stroke and transient ischemic attack (TIA) during 2019 (before COVID-19 period) and 2020 (COVID-19 period). Outcomes included patient characteristics, time from stroke onset to hospital arrival, and in-hospital stroke pathways. Subgroup analyses were performed for an epidemic region (Daegu city and Gyeongsangbuk-do region, the D-G region). Results: The study included 1,792 patients from the pre-COVID-19 period and 1,555 patients from the COVID-19 period who visited hospitals that contribute to the KSR. During the COVID-19 period, the D-G region had two-thirds the number of cases (vs. the pre-CO-VID-19 period) and a significant decrease in the proportion of patients with TIA (9.97%-2.91%). Unlike other regions, the median onset-to-door time increased significantly in the D-G region (361 min vs. 526.5 min, p = 0.016), and longer onset-to-door times were common for patients with mild symptoms and who were in their 60s or 70s. The number of patients who underwent intravenous thrombolysis also decreased during the COVID-19 period, although the treatment times were not significantly different between the 2 periods. Discussion/Conclusion: Korean stroke patients in a CO-VID-19 epidemic region exhibited distinct changes in health-seeking behaviors. Appropriate triage system and public education regarding the importance of early treatment are needed during the COVID-19 pandemic.Y
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