383 research outputs found
Development of Two-Photon Absorbing Smal-Molecular Dyes for Biomedical Imaging Application
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A Ratiometric Two-Photon Fluorescent Probe for Tracking the Lysosomal ATP Level: Direct in cellulo Observation of Lysosomal Membrane Fusion Processes
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Two-photon Ratiometric Imaging of γ-Glutamyl Transpeptidase Unperturbed by pH, Polarity, and Viscosity Changes
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Ratiometric fluorescence detection of anthrax biomarker with Eu(III)-EDTA functionalized mixed poly(diacetylene) liposomes
No full textAnthrax, a bacteriogenic fatal infectious disease that is harmful to humans, requires the early and ready detection
of its bacterial endospores. We report herein the use of poly(diacetylene acid) derived liposomes functionalized
with EuIII-EDTA complexes as a ratiometric fluorescence detection system for dipicolinate, an anthrax biomarker and
major component of the endospores. The red fluorescence of the polymerized liposomes provides a built-in reference
signal to monitor the relative change of the europium luminescence sensitized by the bound dipicolinate relative to
the reference liposome emission. The liposome-based integrated sensing system shows reasonable sensitivity as well
as remarkable selectivity toward dipicolinate over other structurally related analytes. Paper strip sensors based on
the polymerized liposomes are also prepared for the visible detection of dipicolinate.114Nsciescopu
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