4 research outputs found
Forecasting of Climate Changes of Ayeyarwady Delta in Myanmar during 21st Century by MRI-AGCM3.2S Dataset
No full textClimate change is associated with both gradual changes in the long-term temperature and precipitation patterns in an area. Inthis study, MRI-AGCM3.2S was used to simulate the current climate (1981-2005) and the forecasted climate for the near future (2020-2044) and far future (2075-2099). MRI-AGCM3.2S is developed by the Meteorological Research Institute (MRI) and JapanMeteorological Agency (JMA). Linear scaling and lumped quantile mapping methods are used in bias-correction for MRIAGCM3.2S under the Special Report on Emission Scenarios (SRES) of A1B. Bias correction is capable of improving the General Circulation Model (GCM) simulated outputs to a certain degree. In this study, the coefficient of determination (R2) and root mean square error (RMSE) are quantified before and after bias correction. Based on the performances, the lumped quantile mapping technique was identified as a suitable method for correcting the bias. Changes in temperature and precipitation are projected to vary by region and month. The key findings on future climates in each of the regions are presented in terms of temperature increase and precipitation chang
Epidemiological characteristics and real‐world treatment outcomes of hepatitis C among HIV/HCV co‐infected patients in Myanmar: A prospective cohort study
No full textAbstract Background and Aims In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplification of HCV service delivery through task‐shifting among health workers and decentralization to the primary health care level. Between November 2016 and November 2017, a study was conducted to describe the epidemiological data and real‐world outcomes of treating HIV/HCV coinfected patients with generic direct acting antiviral (DAA) based regimens in the three HIV clinics run by nonspecialist medical doctors in Myanmar. Methods HCV co‐infection among people living with HIV (PLHIV) from two clinics in Yangon city and one clinic in Dawei city was screened by rapid diagnostic tests and confirmed by testing for viral RNA. Nonspecialist medical doctors prescribed sofosbuvir and daclatasvir based regimens (with or without ribavirin) for 12 or 24 weeks based on the HCV genotype and liver fibrosis status. Sustained virologic response at 12 weeks after treatment (SVR12) was assessed to determine cure. Results About 6.5% (1417/21,777) of PLHIV were co‐infected with HCV. Of 864 patients enrolled in the study, 50.8% reported history of substance use, 27% history of invasive medical procedures and 25.6% history of incarceration. Data on treatment outcomes were collected from 267 patients of which 257 (96.3%) achieved SVR12, 7 (2.6%) failed treatment, 2 (0.7%) died and 1 (0.4%) became loss to follow‐up. Conclusion The study results support the integration of hepatitis C diagnosis and treatment with DAA‐based regimens into existing HIV clinics run by nonspecialist medical doctors in a resource‐limited setting. Epidemiological data on HIV/HCV co‐infection call for comprehensive HCV care services among key populations like drug users and prisoners in Yangon and Dawei
Additional file 2 of High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar
No full textAdditional file 2. Results of the clinical examination of adolescents aged 10–19 years old on ART and enrolled in the cross-sectional survey at an MSF clinic in Myanmar, by age group
Additional file 1 of High levels of viral repression, malnutrition and second-line ART use in adolescents living with HIV: a mixed methods study from Myanmar
No full textAdditional file 1. Baseline characteristics of adolescents aged 10–19 years old on ART and enrolled in the cross-sectional survey at an MSF clinic in Myanmar, by age group
