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Development of a decision-making procedure for outsourcing engineering services in TxDOT
No full texttextThe trend to outsource the engineering functions in state departments of transportation (DOTs) to private consultants has increased in recent years. However,
most DOTs do not have a strategic approach to the outsourcing of engineering functions or projects. This thesis addresses that gap by examining outsourcing decision-making in the Texas Department of Transportation (TxDOT) and developing a rationalized procedure.
TxDOT, the largest state DOT in terms of annual construction program,expends about 65% of its engineering on consultants. Staff from 18 of TxDOTs 25 districts were interviewed for this research, and Strengths, Weaknesses, Opportunities,
and Threats (SWOT) Analysis is used to identify improvements to the current decision-making processes. A framework is presented for systematic assessment of the outsourcing potential of engineering functions, which would enable TxDOT districts to determine what engineering work to contract out cost-effectively without
sacrificing core competencies.Civil, Architectural, and Environmental Engineerin
Impacts of Ta Buffer Layer and Cu-Ge-Te Composition on the Reliability of GeSe-Based CBRAM
No full textsponsorship: This work was supported by imec's Core Partner Industrial Affiliation Program on Emerging Memories. The review of this article was arranged by Editor P. Du. (Corresponding author: Janaki Radhakrishnan.) (imec's Core Partner Industrial Affiliation Program on Emerging Memories)status: Publishe
Efficacy of sugarcane bagasse to produce bacterial biofilm in water for fish culture
No full textThe present study has been conducted to understand the efficacy of sugarcane bagasse to produce bacterial biofilm in water. The study period was 90 days. Total Plate count (TPC) in water and substrate was estimated on nutrient agar at room temperature by spread plate method. The TPC in water was the highest (2.10 x 104 ml–1) after 45 days. The average TPC of bacteria on bagasse varied from 140.0 (15d) to 30.25 (90d) x104·g–1. The present study demonstrates that the sugarcane bagasse can produce more bacteria in water thereby the fish can effectively utilize biofilm grown on sugarcane bagasse and provision of a substrate reduces the need for artificial feed.---------------------------------------------------------------------------------------------------------Efficacy of sugarcane bagasse to produce bacterial biofilm in water for fish culture M.V. Radhakrishnan and E.SugumaranDepartment of Zoology, Annamalai University, Annamalainagar – 608 002, Tamilnadu, India *Corresponding Author, Email: [email protected] Cite This Article As: M.V. Radhakrishnan, E. Sugumaran. 2010. Efficacy of sugarcane bagasse to produce bacterial biofilm in water for fish culture. J. Ecobiotechnol. 2(2):41-44
Baclofen-induced neurotoxicity in a patient with end-stage renal disease
No full textBaclofen, predominantly excreted by the kidneys is accumulated in patients with renal insufficiency leading to the central nervous system toxicity. Here the author reports a patient with end-stage renal disease on maintenance hemodialysis (HD) who developed drowsiness and became unresponsive within a day after taking single 10 mg dose of baclofen. Patient improved completely after two sessions of HD
A monolithically integrated power JFET and Junction Barrier Schottky diode in 4H silicon carbide
No full textEfficiency of power management circuits depends significantly on their constituent switches and rectifiers. The demands of technology are increasingly running up against the intrinsic properties of Si based power devices. 4H-Silicon Carbide (SiC) has superior properties that make it attractive for high power applications. SiC rectifiers are already a competitive choice and SiC switches have also been commercialized recently. Junction Barrier Schottky (JBS) diodes, which combine the advantages of PN and Schottky, have higher Figure of Merit (FOM) as rectifiers. Among switches, a robust and mature process has been developed for Silicon Carbide Vertical Junction Field Effect Transistors (VJFETs), which currently gives it the highest unipolar FOM. Switches are frequently combined with anti-parallel diodes in power circuits. This thesis describes the development of a SiC-based monolithically integrated power switch and diode. Monolithic integration increases reliability and efficiency, and reduces cost. Because of their superior properties and similarities in fabrication, we chose the SiC VJFET and JBS diode as the switch and rectifier. Detailed design, fabrication and characterization of the integrated switch to block above 800 V and conduct current beyond 100 A/cm2 is explained. In this process, the first physics-based 2-D compact model is developed for reverse leakage in a JBS diode as a function of design parameters. Since the gate-channel junctions of SiC VJFETs cannot be assumed to be abrupt, an existing analytical model for Si VJFETs is extended to account for graded gate-channel junctions. Using these analytical models, design rules are developed for the VJFET and JBS diode. Finite element simulations are used to find the best anode layout of the JBS diode and optimize electric field termination in the integrated device to ensure their capability to operate at high voltage. Finally, a spin-on glass based process is developed for filling the gate trenches of the VJFET to improve long-term robustness in extreme environments. The integrated power switch developed in this thesis points to the attractions of monolithic integration in SiC power circuits. Analytical compact design equations derived here will facilitate faster and easier design of switches and rectifiers for desired circuit operation.Ph. D.Includes bibliographical referencesIncludes vitaby Rahul Radhakrishna
The JRP statistical programs for high speed IBM digital computers [by] B. K. Radhakrishnan and Nils B. Mattsson, with the assistance of Norman A. Starr.
No full texthttp://deepblue.lib.umich.edu/bitstream/2027.42/7195/5/abv5851.0001.001.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/7195/4/abv5851.0001.001.tx
Flexibility in adaptation planning: When, where and how to include flexibility for increasing urban flood resilience
No full textThe magnitude and urgency of the need to adapt to climate change is such that addressing it has been taken up by the United Nations as one of the sustainable development goals - Goal 13 (SDG13) in 2015. SDG13 emphasises the need to strengthen resilience and adaptive capacity to climate related hazards and natural disasters. Coping with urban floods is one of the major needs of climate adaptation, where integration of climate change responses into flood risk management policies, strategies and planning at international, national, regional and local levels is now the norm. However, much of this integration lacks effectiveness or real commitment from stakeholders involved in adaptation planning and implementation. Hence this research has focused on integrating flexibility based adaptation responses into an urban flood risk management context. The research has synthesised flexible adaptation practices from several disciplines including information technology, automobile and aerospace manufacturing. The outcomes of the research are brought together in a framework for structuring local adaptation responses and an adaptation planning process based on flexibility concepts. The outcomes provide a way to assist with the identification of the appropriate nature and type of flexibility required; where flexibility can best be incorporated; and when is the most appropriate time to implement the flexible adaptation responses in the context of urban flooding.Dissertation submitted in fulfilment of the requirements of the Board for Doctorates of Delft University of Technology and of the Academic Board of the UNESCO-IHE Institute for Water Education.Hydraulic Structures and Flood Ris
Journal of Proteomics & Bioinformatics- Open Access www.omicsonline.com Research Article JPB/Vol.2/July 2009 Molecular Characterization of Novel form of Type III Polyketide Synthase from Zingiber Officinale Rosc. and its Analysis using Bioinformatics Meth
No full textCopyright: © 2009 Radhakrishnan EK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Enzymes of Type III polyketide synthase superfamily play an important role in the biosynthesis of medicinal natural products in plants. The PKSs generate the diversity of polyketide derivatives by changing their preference for starter molecules, the number of acetyl additions catalysed and the cyclisation of the polyketide intermediates. The amazing structural features of gingerol and related compounds of ginger (Zingiber officinale Rosc., Zingiberaceae) provide a genomic insight in to the presence of novel forms of PKS. The current study describes the isolation and characterisation of a novel of PKS from Z. officinale using degenerate oligonucleotide based PCR method. The inducible expression of recombinant ZoPKS in E. coli resulted in the formation of a protein with approximate molecular weight of 43kD. The comparative sequence and phylogenetic analysis of ZoPKS shows its significant variation from already identified PKSs. The novelty of the ZoPKS was further confirmed by homology modeling based comparative structural bioinformatics analysis. The novel form of PKS identified i
On Shankar's Counterexample to Lighthill's Lemma
No full textThis paper provides two independent proofs of13; a lemmaa in aerofoil theory due to Lighthill .13; The proofs were provided to the author, in personal communications, by Radhakrishnan, and by13; Lighthill . The paper concludes by pointing out13; the fallacy in the counterexample provided by Shankar
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