1,708 research outputs found
New (Probabilistic) Derivation of Diaz-Metcalf and Pólya-Szegő Inequalities and Consequences
No full textClassical inequalities of Diaz - Metcalf and Pólya - Szegő are generalized to
probabilistic setting which covers the initial deterministic (both discrete and integral) variants.
From these two inequalities, by the probabilistic derivation method further well -
known inequalities are obtained (that ones by Kantorovich, Rennie and Schweitzer)
Mouvance and the medieval author: re-editing Ancrene Wisse
No full textThe paper discusses the theoretical and practical problems of editing the early thirteenth-century guide for anchoresses, Ancrene Wisse, which (in Paul Zumthor's phrase) is an 'oeuvre mouvante', modified repeatedly from an early stage by its author and others
Tele-operated climbing and mobile service robots for remote inspection and maintenance in nuclear industry
No full textD.S. Merezhkovsky and C.G. Jung: General and Special
No full textВ статье рассмотрены особенности трактовки символа в творчестве Д.С. Мережковского и К.Г. Юнга. Показано влияние идей Мережковского на формирование воззрений К.Г. Юнга, проведен сопоставительный анализ их концепций символа как многозначной и универсальной категории, подчеркнуто значение творчества мыслителей для интерпретации исторических событий и осмысления современной общественной ситуации.The article describes the features of the interpretation of the symbol in the works of D.S. Merezhkovsky and K.G. Jung. The author focuses the attention on the influence Merezhkovsky's ideas on the formation of views of Jung, conducted a comparative analysis their conceptions of symbolism as a multi–valued and universal category, stressed the importance thinkers’ works for the interpret historical events and understanding the contemporary social situation
Fully localised edge states in boundary layers
No full textInvestigation of the laminar-turbulent boundary is performed in a boundary-layer flow. Constant homogeneous suction is applied at the wall in order to prevent the spatial growth of the layer, leading to the parallel Asymptotic Suction Boundary Layer (ASBL). Edge tracking is performed in a large computational domain allowing for full spatial localisation of the structures on the laminar-turbulent separatrix. The obtained dynamics of the state goes through calm and bursting phases. During the latter the structure grows in size, shedding vortices downstream of its core which viscously decay during the calm phases. Comparison with the computation in spatially growing boundary layer is made. The influence of the Reynolds number and the path leading from the edge state to turbulent flow are considered
Stem cell myeloproliferative disease and T-lymphoma induced in mice by the ZNF198-FGFR1 fusion gene of human 8p11 myeloproliferative syndrome
No full textBypass transition in boundary layers as an activated process
No full textWe consider the spatio-temporal aspects of the transition to turbulence in a boundary layer above a flat plate exposed to free-stream turbulence. Combining results from the receptivity to free-stream turbulence with the observation of a double threshold from transition studies in e.g. pipe flow we arrive at a physically motivated prediction for the spatial distribution of nucleation events in boundary layers. We use a cellular automaton to implement a complete model for the spatial and temporal evolution of turbulent patches and show that the model reproduces the statistical features of the boundary layer remarkably well. The success of the modeling shows that bypass transition occurs as a spatiotemporally activated process, where transition is triggered by critical fluctuations imported from the free-stream turbulence
[Interview Minutes with D.S. Myer, WRA National Director, March 18, 1944]
No full textMeeting minutes between incarceree-led Tule Lake Camp government and War Relocation Authority Director D.S. [Dillon Seymour] Myer. Question-answer session between Co-ordinating Committee and Myer. Includes questions about legitimacy and self-governance of Co-ordinating Committee, concerns about camp food, employment, and martial law in the camp.The Willard Schmidt collection, documents some of the administrative duties of Willard Schmidt, the Chief of Internal Security for the War Relocation Authority and the Tule Lake incarceration/segregation camp. This collection contains administrative records and photos documenting the Tule Lake camp, the largest incarceration camp with a peak population of 18,789 and with the most turbulent history. In 1943, the camp was turned into a segregation center to house "disloyal" Japanese Americans relocated from other camps based on their answers to a confusing loyalty questionnaire. The camp endured martial law from November 1943- Jan 1944 after escalating protests and unrest. The hostile environment of the camp lead to many incarcerees renouncing their American citizenship upon the end of incarceration, a process which took 14 years to reverse if they did not wish to be deported to Japan
The Benefits of Being Economics Professor A (and not Z)
No full textAlphabetic name ordering on multi-authored academic papers, which is the convention in the economics discipline and various other disciplines, is to the advantage of people whose last name initials are placed early in the alphabet. As it turns out, Professor A, who has been a first author more often than Professor Z, will have published more articles and experienced afaster growth rate over the course of her career as a result of reputation and visibility. Moreover, authors know that name ordering matters and indeed take ordering seriously: Several characteristics of an author group composition determine the decision to deviate from the default alphabetic name order to a significant extent.performance measurement, incentives, economists, name ordering
Updates on the hematologic tumor microenvironment and its therapeutic targeting
No full textIn this review article, we present recent updates on the hematologic tumor microenvironment following the 3rd Scientific Workshop on the Haematological Tumour Microenvironment and its Therapeutic Targeting organized by the European School of Hematology, which took place at the Francis Crick Institute in London in February 2019. This review article is focused on recent scientific advances highlighted in the invited presentations at the meeting, which encompassed the normal and malignant niches supporting hematopoietic stem cells and their progeny. Given the precise focus, it does not discuss other relevant contributions in this field, which have been the scope of other recent reviews. The content covers basic research and possible clinical applications with the major therapeutic angle of utilizing basic knowledge to devise new strategies to target the tumor microenvironment in hematologic cancers. The review is structured in the following sections: (i) regulation of normal hematopoietic stem cell niches during development, adulthood and aging; (ii) metabolic adaptation and reprogramming in the tumor microenvironment; (iii) the key role of inflammation in reshaping the normal microenvironment and driving hematopoietic stem cell proliferation; (iv) current understanding of the tumor microenvironment in different malignancies, such as chronic lymphocytic leukemia, multiple myeloma, acute myeloid leukemia and myelodysplastic syndromes; and (v) the effects of therapies on the microenvironment and some opportunities to target the niche directly in order to improve current treatments
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