1,930 research outputs found
Extracellular Matrix Remodeling with Focus on Biochemical Markers in Liver Fibrosis: Limitations and Possibilities
No full textAdvocating for the implementation of the new nomenclature for steatotic liver disease: A call to action for the national associations
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Political directives
No full textTitle: Wskazania polityczne (Political directives) Originally published: Ognisko: książka zbiorowa wydana dla uczczenia 25 letniej pracy T. T. Jeża, Warsaw, K. Kowalewski, 1882 Language: PolishThe excerpts used are from Janina Kulczycka-Saloni, Pozytywizm, (Warsaw: PZWS, 1971), pp. 235–240. About the author Aleksander Świętochowski [1849, Stoczek (in Podlachia, present-day east Poland) – 1938, Gołotczyzna (central Poland)]: politician and writer. Aleksander Świetochowski, like many other adhe..
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
No full textScreening for liver fibrosis in the general population: a call for action
No full textLiver cirrhosis is one of the main causes of death and disability-adjusted life-years worldwide. Generally, cirrhosis develops after a long period of liver-cell injury that leads to the deposition of collagen, leading to progressive fibrosis and nodule formation in the liver tissue. Most patients are diagnosed in late stages when liver decompensation or liver cancer develops. The diagnosis is rarely made in early stages—when liver fibrosis is mild to moderate but cirrhosis is not yet established—because the disease is asymptomatic. No strategies for detection of liver fibrosis at these early stages have been developed, but therapies are more effective in early stages than late stages of chronic liver diseases, so enabling early detection is an important research topic. Non-invasive methods for assessing liver fibrosis have been developed, of which the most commonly used are transient elastography—which estimates liver fibrosis by measuring liver stiffness—and serum biomarkers of fibrosis. Studies have shown that 6–7% of the adult population without known liver disease have liver fibrosis, mostly associated with non-alcoholic fatty liver disease. These data suggest that programmes of screening for liver fibrosis in the general population should be assessed.</p
Screening studies of transient elastography and FibroTest in the general population – Authors' reply
No full textInterpreting Wage Bargaining Norms
No full textFrom the mid-1990s onwards, Swedish wage bargaining has been characterised by informal co-ordination of the wage claims of big unions and bargaining cartels. In particular, it has been understood that the manufacturing sector should lead by first agreeing on a pay increase, whereafter the service sector and public sector unions choose a similar increase. We analyse his setup with two possible theoretical interpretations: (i) the manufacturing sector as a tackelberg leader and (ii) a normative role for the manufacturing sector’s pay increase, upported either by unmodelled social pressure or a modeled loss aversion (envy) of the heltered sector unions. The conclusion of the analysis is that the normative or leading role of one sector – in the Swedish case the manufacturing sector – can potentially bring big benefits for employment and output. Generalising an idea suggested by Lars Calmfors and Anna Larsson, our analysis also generates a rudimentary theory of why the wage increase norm sometimes binds and sometimes not. A comparison of the model predictions and the observed outcomes of the last five wage bargaining rounds in Sweden suggests that the model is generally consistent with the empirical observations: wage moderation and norm observance are stronger when the manufacturing industry’s initial relative wage is low.wage bargaining; bargaining co-ordination
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