1,154 research outputs found
ASO Author Reflections: Vascular Resection in Perihilar Cholangiocarcinoma Surgery
No full textvascular resection in hilar cholangiocarcinom
FDG PET/CT during neoadjuvant chemotherapy may predict response in ER-positive/HER2-negative and triple negative, but not in HER2-positive breast cancer
No full textAbstract not availableBas B. Koolen, Kenneth E. Pengel, Jelle Wesseling, Wouter V. Vogel, Marie-Jeanne T.F.D. Vrancken Peeters, Andrew D. Vincent, Kenneth G.A. Gilhuijs, Sjoerd Rodenhuis, Emiel J.Th. Rutgers, Renato A. Valdés Olmo
Retour d\u92expériences après la tempête Xynthia en France, leçons pour les Pays Bas; les dégâts suite à l\u92inondation
No full textLe 28 février 2010, vers 2 heures du matin, la tempête Xynthia atteint la côte occidentale de la France. A plusieurs endroits, les digues, dunes et d\u92autres ouvrages cédèrent, donnant lieu à des inondations du littoral. Plus de 50.000 hectares de terres furent inondées. Au total, la France compta 47 morts suite à la tempête, la plupart d\u92entre eux suite à la crue. Essentiellement les régions de la Vendée et de la Charente-Maritime endurèrent de terribles privations. Les dégâts et les victimes ne sont pas uniquement la conséquence du phénomène naturel, mais également des interventions de l\u92homme ou le manque de celles-ci. Les Pays-Bas pourraient tirer des leçons de ces inondations côtières françaises. Les circonstances aux Pays-Bas et en France sont, dans une grande mesure, comparables. La France, elle aussi, connaît des zones côtières à basse altitude sensibles aux inondations. Certes, le niveau de protection aux Pays-Bas est plus élevé, mais une inondation aux Pays-Bas est aussi bien concevable. Tout comme en France, une inondation du littoral néerlandais est causée par une combinaison de la marée, d\u92une tempête et d\u92une surcote. Les législations et les réglementations présentent des concordances ; leurs bases datent de l\u92époque de Napoléon. Ce livre décrit l\u92inondation par la tempête Xynthia et ses conséquences. Nous en tirons des leçons et nous formulons des avis pour les Pays-Bas. Nous cherchons à nous associer à une protection contre l\u92inondation à trois volets: la prévention, l\u92aménagement du territoire et la maîtrise des catastrophes
Inventory for a Reverse Journey. Photographic Image and Found Object - An investigation of travel and material transformation as a paradigm of artist's practice: Ed Ruscha, Douglas Huebler, Bas jan Ader, Jimmie Durham, Gustav Metzger, Kurt Schwitters & Cian Quayle.
No full textInventory for Reverse Journey is the title of a collection of photographic artefacts and found objects, which I have collected over the last twenty years. The title refers to one specific type of artist's journey, which is applicable to the `chronotope' of my archive, as a `metaphorical journey in space and time' (Bakhtin 1981, p. 81). The `city',`provincial town', `road', `threshold' and `interior' are recurrent motifs, which Bakhtin fused together to describe the historical evolution of the novel in relation to its different genres. Bakhtin's motifs are expanded as the basis of an evolutionary nomenclature of the artist's-journey, as a form of spatial mapping and identity formation. Alongside other sources from literature (Alain Robbe-Grillet), cinema (Michelangelo Antonioni), psychoanalysis (Kierkegaard) and critical theory (Walter Benjamin) I have developed a theoretical framework, which initially originated in an empirical process, that is reflected in the antecedents of this project. The research process, as a journey itself, has concretised this approach within a systems-based practice. This is mirrored in the work of the artists under investigation, as their differences and similarities are highlighted within a broad contextual analysis. Accordingly the tone of the writing shifts its register at different points in the thesis.
My journey is just one example of several paradigmatic formations of `travel' as a strategy, which investigates the work of six different artists, as a voluntary or involuntary form of exile. A deskilled use of the photographic image is examined in the work of Ed Ruscha, Douglas Huebler and Bas jan Ader in the spatial mapping of their chosen locations. The work of these artists manifests travel, as a strategy, in a benign form of regional and expatriate exile. The investigation shifts its focus from the New World to Europe, where the work of Jimmie Durham, Gustav Metzger and Kurt Schwitters is analysed in relation to their transformation of found objects and materials, and their relationship with a former 'home'. Their position registers different degrees of the `impossibility of return' to a point of origin, which exists in the mind rather than as a physical location. The transience of their work, and use of disparate materials, is counterbalanced by their physical presence in the work. Conversely Ader, Huebler and Ruscha are linked by a scale of decreasing visibility, as they are sublimated within their work in the formation of, what is now construed as, a unique photographic presence. The starting point for which is a return to the formative years of conceptualism in the 1960's, which set the scene for Durham and Metzger from the 1970's onwards. The spectre of Schwitters practice of forming (Formung) and unforming (Entformung) is significant for my analysis of the dematerialisation of the art-work and artist, by processes of series and repetition, distance and proximity, movement and stasis. Although `travel' is a ubiquitous term, I continue to use it as a portmanteau, which carries with it the themes and `salient' features of a typology of artist's journeys. In a moment of perceived obsolescence as digital information systems engender a culture of `selective-amnesia', these thoughts have informed my work, which runs parallel to the artist case-studies, and the material transformation of the photographic image and found object
BAS Adelie Penguin Diet
No full textProgress Code: completed<b>Purpose</b><br/>By monitoring the diets of key predators over a number of years, we can examine the relative availability of different prey items, as well as the particular characteristics of their foraging behaviour. Penguin diet variability is a key CEMP parameter and with the reduction in lavage sampling it is important to identify and assess alternative, less invasive methods as potential supplementary approaches for studying penguin diet. Diet analysis using DNA in faecal material is one alternative method which eliminates the need to handle the birds and is non-invasive.June 2018<br/>Adélie penguin scats were collected from Signy Island (South Orkney Islands) during crèche (December/January) 2014/15 and 2015/16 and stored in 80% Ethanol. DNA was extracted from ~30 mg of faecal material using a Promega ‘Maxwell 16' instrument and a Maxwell® 16 Tissue DNA kit. <br/>A total of 450 samples were analysed: 30 extractions per week for 2015 and 60 per week for samples collected in 2016.<br/><br/>Three DNA markers providing different taxonomic information were amplified from penguin faecal DNA. First, ALL faecal DNA samples were characterised using a highly conserved metazoan primer set that amplifies a region of the nuclear 18S gene. In addition, a subset of faecal samples from each year were also characterised with two other primer pairs that amplify a region of the mtDNA 16S gene to allow species-level identification for most fish (16S_Fish) and krill (16S_Krill) species respectively. During amplification of markers, the products were tagged with a unique pair of index primers allowing samples to be pooled and sequenced (2x150bp) on a MiSeq high-throughput DNA sequencer. <br/>- See Adelie Pengiun Diet CCAMLR paper for all of the primer/PCR details<br/>- See BAS Adelie 18s Krill and Fish subset excel spreadsheet for sample details.<br/>- See BAS Adelie 18s ALL samples fastq for 18s fastq files<br/>- See BAS Adelie 16s Krill subset fastq for 16s krill fastq files<br/>- See BAS Adelie Fish subset fastq for 16s fish fastq files<br/>#####################################################################################<br/>November 2018<br/>In addition we also amplified all 450 samples with the 16S_Fish marker.<br/>- See Adelie Experiment Details 16s Fish for sample details, plate layout, first and second round PCR and miseq sheet.<br/>- See BAS Adelie Fish ALL Samples fastq for 16s fish fastq file
"Causes, Consequences and Dynamics of 'Complex' Distributions of Technological Activities: The Case of Prolific Inventors"
No full textWe provide a framework for understanding the causes and consequences of the observed shapes of the distributions of individual inventors' productivities. We review a literature that begins with Lotka's (1926) "law" regarding the persistence of variability in scientific productivity at any point in time and also over time. We discuss use of the "power law" and the Pareto distribution to describe and explain the empirical distributions. We focus on the upper parts of the frequency distributions for inventors exploring the processes underlying knowledge accumulation at the individual level, including its features, characteristics, and structural trends. Finally we explore the specific processes by which these individuals create, maintain, and increase knowledge accumulation as their careers evolve.patents, inventors, prolific, lotka
Fig. 10 Pyrenopeziza rubi. a Habitus. b in Emendations to tissue typology in discomycetes
No full textFig. 10 Pyrenopeziza rubi. a Habitus. b Textura angularis typica in the ectal excipulum. Drawing by C. Bas, photograph by the author (coll. C. Bas no. 1442; 3.6.1958; Netherlands, Oegstgeest, "Oud-Poelgeest"; on dead, 3-year old stems of Rubus idaeus; herb. L 958.021–363)Published as part of Hengstmengel, Jan, 2020, Emendations to tissue typology in discomycetes, pp. 543-558 in Mycological Progress 19 (6) on page 552, DOI: 10.1007/s11557-020-01577-5, http://zenodo.org/record/502025
The impact of labor market regulations
No full textThe authors investigate the impact of labor market regulations in settings where compliance is incomplete. They review some stylized facts about labor market behavior, present an analytical model that may explain such behavior, and provide a checklist for assessing the distortionary impact of a regulation such as the minimum wage. They take as their starting point the limited evidence about the distortionary effects of such regulations and argue that there may be natural limits on the efficiency losses engendered by labor market regulations. First, the regulations may not be binding at market equilibrium. For example, minimum wages may be set so low that they are ineffective. Second, even if they are binding, the relevant elasticities of supply and demand may be so low that the regulations have little impact on efficiency. Third, even if the regulations are binding and elasticities are sizable, compliance may be low. The authors argue that the likelihood of compliance will be greatest when the regulations are binding and the relevant elasticities are sizable. That is, if the distortionary costs of regulations are not rendered insignificant by the first two reasons, then the returns to noncompliance will be high and, other things being equal, employers will evade or avoid the regulations, thereby minimizing the imact on efficiency. The argument rests on profit maximization subject to a hard budget constraint. Public enterprises, which are not concerned only with profit maximization and often have softer budget constraints than the private sector, may be more willing to conform to profit-reducing regulations, but in this case the authors argue that compliance may reduce already-existing efficiency losses.Environmental Economics&Policies,Health Monitoring&Evaluation,Labor Policies,Public Health Promotion,Banks&Banking Reform,Health Monitoring&Evaluation,Banks&Banking Reform,Municipal Financial Management,Poverty Assessment,Environmental Economics&Policies
Low-Wind Turbines in the Dutch Power Grid: Understanding the Effect of Low-Wind Turbines on Storage Capacity and System Costs
No full textOne of the major challenges that the world currently faces is the energy transition. The aim of most countries worldwide is to reduce their carbon footprint, in order to slow climate change. Fossil fuel powered energy generation is replaced with an increasing share of variable renewable energy sources such as wind and solar energy. Because of the inherent uncertainty and intermittency of these renewable power sources, large scale energy storage is considered inevitable in order to mitigate the mismatch between supply and demand. However, storage comes at a cost and uses precious materials, of which there might not be sufficient. Therefore, a whole range of solutions is being researched and implemented. Currently, it is not well-known what mix of which solutions will be the most technologically and economically effective. The Low-Wind turbine is a new turbine concept, specifically designed for low wind speed conditions, combined with a low rated and cut-out wind speed. The reduced normative loads on the blades enable a re-design of several components, which ultimately results in lower costs. This new turbine concept aims to be a system-friendly turbine, by decreasing the mismatch between production and demand and thereby reducing the total amount of storage or overplanting required in the system. This research assesses the effectiveness of the Low-Wind turbine in the Dutch energy grid, when it is predominantly powered by renewable energy sources. A power model, specifically developed for this research, simulates the power flows and optimises the seasonal storage required in order to meet the constraints. The power model is simulated for a range of installed turbines, consisting of combinations of conventional and Low-Wind turbines. This research also carries out a preliminary design off a Low-Wind turbine, based of a reference turbine, in order to determine its costs. The result of this study show that, if the cost of the installed wind farms dominate the costs, Low-Wind turbines does not provide a cost-effective solution to minimising system costs. However, the results also show that, in a situation where total costs are dominated by storage cost, the Low-Wind turbine can provide a cost-effective alternative to conventional turbines. The results also show that, for high overplanting factors, Low-Wind turbines and conventional turbines provide a similar effect on the reduction of system costs, but at lower costs.Electrical Engineering | Sustainable Energy Technolog
Family planning success in two cities in Zaire
No full textBoth projects described here, Matadi and Kananga, helped health providers in those two cities offer clinical family planning services. But their approaches differed markedly. The family education program in Matadi concentrated on pioneering community-based distribution of contraceptives, with carefully supervised distributors. The Kanaga Project emphasized clinical supervision and pleasing the clients; introduced social marketing with loose supervision of retailers; and provided an information team skilled in face-to-face group meetings, plus a weekly radio program. Four factors common to both projects seemed to contribute to their success: The single-minded dedication of staff members to making family planning work. An uninterrupted supply of affordable contraceptive methods available through outlets at many locations. Enough organizational autonomy to be able to respond to problems as they arose. Such autonomy made project personnel identify more with project goals and feel responsible for achieving project objectives. Regular and supportive supervision of those responsible for service delivery. Both projects emphasized regular contact with clinic personnel - Matadi also included distributors. These contacts bolstered morale by showing that the project administration was closely following service providers'activities and by transmitting to providers the staff's enthusiam for project activities. Supervisory visits included administrative functions such as collecting service statistics and controlling inventory, but these activities were handled in a friendly, nonthreatening manner that encouraged service providers to perform their tasks well. The fourth factor is adequate funding. Both projects had special funding that allowed them to experiment with approaches for increasing contraceptive prevalence. That funding may partly explain their organizational autonomy and may have contributed to the sense of purpose and esprit de corps that developed among project staff. Larger-scale programs in Zaire have operated with significant financial constraints, so it would be unfair to compare them with these more successful projects. Special funding does not guarantee project success but may make it far more likely, conclude the authors.Health Monitoring&Evaluation,Adolescent Health,ICT Policy and Strategies,Early Child and Children's Health,Reproductive Health
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