223 research outputs found
sj-pdf-1-vmj-10.1177_1358863X211033649 – Supplemental material for Exercise therapy referral and participation in patients with peripheral artery disease: Insights from the PORTRAIT registry
No full textSupplemental material, sj-pdf-1-vmj-10.1177_1358863X211033649 for Exercise therapy referral and participation in patients with peripheral artery disease: Insights from the PORTRAIT registry by Tripti Gupta, Patrick Manning, Dhaval Kolte, Kim G Smolderen, Nancy Stone, Jessica G Henry, Jingyan Wang, Kensey L Gosch, Christopher J White, John Spertus and J Dawn Abbott in Vascular Medicine</p
10.1177_1358863X18816816_supplementary_material_figure2 – Supplemental material for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database
No full textSupplemental material, 10.1177_1358863X18816816_supplementary_material_figure2 for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database by Fabio V Lima, Dhaval Kolte, David W Louis, Kevin F Kennedy, J Dawn Abbott, Peter A Soukas, Omar N Hyder, Shafiq T Mamdani and Herbert D Aronow in Vascular Medicine</p
10.1177_1358863X18816816_supplemental_material_tables – Supplemental material for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database
No full textSupplemental material, 10.1177_1358863X18816816_supplemental_material_tables for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database by Fabio V Lima, Dhaval Kolte, David W Louis, Kevin F Kennedy, J Dawn Abbott, Peter A Soukas, Omar N Hyder, Shafiq T Mamdani and Herbert D Aronow in Vascular Medicine</p
10.1177_1358863X18816816_supplementary_material_figure1 – Supplemental material for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database
No full textSupplemental material, 10.1177_1358863X18816816_supplementary_material_figure1 for Thirty-day readmission after endovascular or surgical revascularization for chronic mesenteric ischemia: Insights from the Nationwide Readmissions Database by Fabio V Lima, Dhaval Kolte, David W Louis, Kevin F Kennedy, J Dawn Abbott, Peter A Soukas, Omar N Hyder, Shafiq T Mamdani and Herbert D Aronow in Vascular Medicine</p
Modeling wing tank flammability:
No full textAn investigation into the fire safety of a wing fuel tank has been performed to aid in the effort to eliminate or reduce the possibility of a wing fuel tank explosion in a commercial aircraft. A computational model is built to predict the generation of flammable mixtures in the ullage of wing fuel tanks. The model predicts the flammability evolution within the tank based on in-flight conditions of a wing fuel tank. The model is validated through supporting experiments performed in an altitude chamber, the wind tunnel facility as well as data obtained from flight tests. The results from the experiments are compared to the computational results. Computational results from the altitude chamber follow the general trend of the experimental results, but produce them at a different flash point. This is due to the replenishment of species with lower flash point at the surface of the fuel which emulates the flash point of the entire fuel to be lower. Experimental results for the aluminum wing tests from the wind tunnel experiments are in good agreement with the computational results as well.
A simpler model is developed from a program that calculates fuel air ratio within the ullage of fuel tanks in order to reduce the required number of inputs to the model. This model is applied to the data sets for the experiments performed in the altitude chamber and wind tunnel. For the tests conducted in the altitude chamber, the correlation estimates the hydrocarbon concentrations extremely well during ascent and descent. During the on-ground condition the estimation is good, but not as accurate as the ascent or descent conditions. For the tests conducted in the wind tunnel, the computational values follow the general trend of the experimental values, but the computational values estimates the total hydrocarbon concentration approximately 10% lower than the experimental value consistently.
Flammability studies are also performed in order to track the effects of temperature, pressure, and oxygen concentration on the upper and lower flammability limits. For the temperature and pressure profiles considered in this work, it is found that the temperature and pressure effects on the flammability limits are minimal. In contrast, the oxygen concentration has a significant effect on the flammability limits of the vapor; the flammable region narrows with a decrease in oxygen concentration.M.S.Includes bibliographical references (p. 100-101)by Dhaval D. Dadi
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Evaluating Third Generation Valve System Performance and Pacemaker Implantation Variability After Transcatheter Aortic Valve Replacement
No full textAbstract
Background: The choice of transcatheter aortic valve replacement (TAVR) prosthesis
is crucial in optimizing short- and long-term outcomes.
Objective: To conduct a meta-analysis comparing outcomes of 3rd generation balloon-
expandable valves (BEV) vs. self-expanding valves (SEV).
Methods: Electronic databases were searched from inception to June 2023 for studies
comparing 3rd generation BEV vs. SEV. Primary outcome was all-cause mortality.
Secondary outcomes included clinical and hemodynamic end points. Random effects
models were used to calculate pooled odds ratios (ORs) or weighted mean differences
(WMDs).
Results: The meta-analysis included 16 studies and 10,174 patients (BEV: 5,753 and
SEV: 4,421). There were no significant differences in 1-year all-cause mortality (OR
1.15, 95% CI 0.89-1.48) between 3rd generation BEV vs. SEV. TAVR with 3rd generation
BEV was associated with a significantly lower risk of TIA/stroke (OR 0.62, 95% CI 0.44-
0.87), permanent pacemaker implantation (PPI, OR 0.55, 95% CI 0.44-0.70), and
≥moderate paravalvular leak (PVL, OR 0.43, 95% CI 0.25-0.75), and higher risk of
≥moderate patient-prosthesis mismatch (PPM, OR 3.76, 95% CI 2.33-6.05), higher
mean gradient (WMD 4.35, 95% CI 3.63 to 5.08), and smaller effective orifice area
(EOA, WMD -0.30, 95% CI -0.37 to -0.23), compared with SEV.
Conclusion: In this meta-analysis, TAVR with 3rd generation BEV vs. SEV was
associated with similar all-cause mortality, lower risk of TIA/stroke, PPI, and ≥moderate
PVL, but higher risk of ≥moderate PPM, higher mean gradient, and smaller EOA. Large,
adequately powered randomized trials are needed to evaluate long-term outcomes of
TAVR with latest generations of BEV vs. SEV.
Abstract
Background: Permanent pacemaker implantation (PPI) remains the most common
complication after transcatheter aortic valve replacement (TAVR).
Methods: We analyzed data from the 2019 Nationwide Readmissions Database to
identify 34,830 patients who underwent TAVR across 398 hospitals. The primary
outcome of interest was new PPI in-hospital or within 30 days post-discharge. Mixed
effects logistic regression models were used to examine hospital-level variation in rates
and timing (in-hospital vs. post-discharge) of new PPI after TAVR.
Results: The overall PPI rate was 9.9% (84.5% in-hospital and 15.5% post-discharge).
The median (IQR) hospital-level PPI rate was 8.7% (5.4% to 12.9%) with wide variation
across hospitals (range: 0% to 54.5%). Similarly, there was substantial hospital-level
variation in the timing of PPI. The median (IQR) proportion of post-discharge PPI at the
hospital level was 13.3% (0% to 25.0%), ranging from 0% to 100%. After adjusting for
patient-level covariates, there was significant hospital variation in PPI rates (median
OR: 1.49; 95% CI: 1.41-1.58) and timing (median OR: 1.54; 95% CI: 1.26-1.82), which
persisted even after addition of hospital-level covariates to the model.
Conclusions: Approximately 1 in 10 patients underwent PPI after TAVR, and 15% of
PPI were performed post-discharge. There is substantial hospital-level variation in rates
and timing of PPI after TAVR, which is not entirely explained by differences in patient
and hospital characteristics. Future studies are needed to understand the reasons
underlying hospital variation in PPI, and to identify evidence-based practices and
processes of care associated with decreased risk of PPI post-TAVR
Understanding the association between hypertensive disorders of pregnancy and peripartum cardiomyopathy
No full textTranscatheter edge‐to‐edge tricuspid valve repair for functional tricuspid regurgitation: does aetiology matter?
No full text
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