6,864 research outputs found
Interferon-gamma (IFN-) induce de novo protein synthesis of both membrane and soluble intercellular adhesion molecule-1 in normal human bronchial epithelial cells
Knight Commission Company (SC 2154)
Finding aid only for Manuscripts Small Collection 2154. Letter from Knight Commission Company, Louisville, Kentucky, to Emerson Nale, Salem, Indiana, soliciting consignments of livestock and quoting market prices for steers, cows, bologna bulls, calves, hogs, sheep and lambs
Knight, Lillian Eleanor, 1919-2003 (SC 1580)
Finding aid and digital copy of original for Manuscripts Small Collection 1580, a reminiscence written by Lillian Eleanor Knight concerning the 1937 Flood in Louisville, Kentucky
SC author and illustrator Kate Salley Palmer signing book
Photograph of SC author and illustrator Kate Salley Palmer signing boo
Nuclear quadrupole hyperfine structure in slightly asymmetric rotor molecules
"June 10, 1949." Based on a thesis.Bibliography: p. 23.Army Signal Corps Contract No. W36-039-sc-32037. Project No. 102B. Dept. of the Army Project No. 3-99-10-022.Geoffrey Knight, Jr. [and] B.T. Feld
Book signing by SC author and illustrator Kate Salley Palmer
Photograph of Book signing by SC author and illustrator Kate Salley Palme
Human rhinovirus selectively modulates membranous and soluble forms of its Intercellular Adhesion Molecule-1 (ICAM-1) receptor to promote epithelial cell infectivity
Human rhinoviruses are responsible for many upper respiratory tract infections. 90% of rhinoviruses utilize intercellular adhesion molecule-1 (ICAM-1) as their cellular receptor, which also plays a critical role in recruitment of immune effector cells. Two forms of this receptor exist; membrane-bound (mICAM-1) and soluble ICAM-1 (sICAM-1). The soluble receptor may be produced independently from the membrane-bound form or it may be the product of proteolytic cleavage of mICAM-1. The ratio of airway epithelial cell expression of mICAM-1 to the sICAM-1 form may influence cell infectivity and outcome of rhinovirus infection. We therefore investigated the effect of rhinovirus on expression of both ICAM-1 receptors in normal human bronchial epithelial cells. We observed separate distinct messenger RNA transcripts coding for mICAM-1 and sICAM-1 in these cells, which were modulated by virus. Rhinovirus induced mICAM-1 expression on epithelial cells while simultaneously down-regulating sICAM-1 release, with consequent increase in target cell infectivity. The role of protein tyrosine kinases was investigated as a potential mechanistic pathway. Rhinovirus infection induced rapid phosphorylation of intracellular tyrosine kinase, which may be critical in up-regulation of mICAM-1. Elucidation of the underlying molecular mechanisms involved in differential modulation of both ICAM-1 receptors may lead to novel therapeutic strategie
Large Reduction in the -axis Knight Shift on UTe with = 2.1 K
Spin susceptibility in the superconducting (SC) state was measured in the
higher-quality sample of uranium-based superconductor UTe by using
Knight-shift measurements for a magnetic field along all three crystalline
axes. In the higher-quality sample, the SC transition temperature
is about 2.1 K, and the residual electronic term in the specific heat is almost
zero. The NMR linewidth becomes narrower and is almost half of that in the
previous sample with K when and .
Although the Knight-shift behavior was not so different from the previous
results for , and , a large reduction in Knight shift along
the axis was observed, in contrast with the previous -axis Knight shift
result. We discuss the origin of the difference between the previous and
present results, and the possible SC state derived from the present results.Comment: 7 pages, 6 figures, including supplemental material
Wilgus, Donald Knight, 1918-1989 (SC 3401)
Finding aid and scan (Click on Additional Files below) for Manuscripts Small Collection 3401. Letter, 25 July 1960, to friends from Donald Knight Wilgus and family, Los Angeles, California, describing their activities and travel since moving to California, including Wilgus’s work at the University of California, Los Angeles. Includes a review of Wilgus’s book, Anglo-American Folksong Scholarship Since 1898, and the premier issue (1963) of Hootenanny: The National Folk Singing Magazine, with an article about Wilgus and UCLA’s folk music studies program
High-resolution clean-sc
In this paper a high-resolution extension of CLEAN-SC is proposed: HR-CLEAN-SC. Where CLEAN-SC uses peak sources in “dirty maps” to define so-called source components, HR-CLEAN-SC takes advantage of the fact that source components can likewise be derived from points at some distance from the peak, as long as these “source markers” are on the main lobe of the Point Spread Function (PSF). This is very useful when sources are closely spaced together, such that their PSFs interfere. Then, alternative markers can be sought in which the relative influence by PSFs of other source positions is minimised. For those markers the source components better agree with the actual sources, which allows for better estimation of their locations and strengths. This paper outlines the theory needed to understand this approach and discusses applications to 2D and 3D microphone array simulations with closely spaced sources
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