102 research outputs found
Copyright on Virtual Items in Virtual Worlds:Governance, Copyrightability, Infringement, Liability
No full textCorrection to : Cost-Effectiveness of Parent–Child Interaction Therapy in Clinics versus Homes : Client, Provider, Administrator, and Overall Perspectives (Journal of Child and Family Studies, (2018), 27, 10, (3329-3344), 10.1007/s10826-018-1159-4)
No full textThe original version of this article unfortunately contained a mistake. The Author contributions section currently states: “A.F.: designed and conducted data analyses for this study, supervised by B.Y. with input by T.F. A.F. and T.F. assisted B.Y. in writing and revising the manuscript.” In fact, B.Y. and T.F. assisted A.F. in writing and revising the manuscript. Although T.F. and B.Y. were both involved in the writing, primary credit should go to A.F. (Alexis French, the first author). The authorship order above is accurate.</p
The Effect of Electro-Magnetic Stirring on the Weld Microstructure of Aluminium Alloys
No full textTechnische MateriaalwetenschappenMechanical, Maritime and Materials Engineerin
A novel network prediction error identification method
No full textWith advancing technology, systems are becoming increasingly interconnected and form more complex networks. Additionally, measurements are more available due to cheaper sensors. Hence there is a need for identification methods specifically designed for networks. System identification is a wide-spread technique that handles open-loop and closed-loop identification problems well, and has explicit consistency and variance results for them. The application of these methods to complex networks is currently under development. Several methods have been proposed in order to obtain consistent estimates. Beside consistency, the variance of the obtained estimates is also crucial because the variance defines confidence regions for the model. A common feature when studying dynamic networks is that measurements can be taken at various locations in the network. These measurements are taken using sensors, which in reality always have some noise. In this thesis it is shown that combining the data of multiple (noisy) sensors to estimate a network internal variable can be beneficial for the estimate’s variance, even if the sensors are measuring different internal variables. This multiple measurements phenomenon is studied and its insight is used to devise a novel network system identification method: the partial tailor-made method. It is shown that the partial tailor-made method provides consistent estimates with lower variance than the celebrated two-stage method.Delft Center for Systems and ControlMechanical, Maritime and Materials Engineerin
Recommended from our members
The Holbrook bequest for commemorative plaques: tradition, narrative and 'local patriotism' in Victorian Nottingham
No full textMotion control of a contactless stage
No full textIn the manufacturing process of flat panel displays (FPD), such as the making of the photomasks and the lithographic process of the glass substrates, the demand for a larger but thinner substrate is increasing. Consequently, the moving stage of these manufacturing machines become larger in size and heavier in weight. The high velocity and acceleration specifications for positioning a moving stage of several tons will require much more power and higher power rate output than any usual positioning tasks. One solution to eliminate the moving mass of the stage is to use a contactless stage. A contactless positioning stage which is capable of controlling a 100 mm wafer in three in-plane degrees of freedom has been developed successfully in the Mechatronic System Design group of the Precision and Microsystems Department. The deployed controller on the contactless stage is a decoupled three-loop Single Input Single Output (SISO) cascaded controller designed by classical loop shaping methods. An initial study shows that the in-plane rotational DoF is disturbed when the center of mass of the wafer is moved from the center of the concatenated air actuators and the planar translational axes are accelerating or decelerating. In addition, the power spectral densities of the measured pressure signals indicate that a high power pressure disturbance affects each control pressure channel. Therefore, the contactless positioning stage should be treated as a Multi Input Multi Output (MIMO) system and controlled with control schemes tailored to the wafer dynamics and the spectrum of disturbances as a potential alternative positioning mechanism at nano/micro levels. In this thesis, the goal is to develop a three in-plane degrees of freedom, multivariable model of the contactless stage, and identify its dynamics or estimate its parameters. With a determined control configuration, design and develop control schemes on the contactless stage that achieves a positioning specification with sub-micrometer precision when performing positioning tasks similar to an industrial precision positioning stage used in FPD manufacturing. With a cascaded control scheme, the dynamics of the contactless stage consist of pressure dynamics and wafer dynamics. The pressure dynamics of the air channels are identified by the Closed-loop Multivariable Output Error Subspace (CL-MOESP) algorithm first. Then the wafer dynamics are modeled from the Newton-Euler equations and the model parameters with disturbance forces in plane are estimated with an extended Kalman filter. Both dynamic models are validated by the comparisons of the frequency response functions (FRFs) of the derived models with the measured FRFs of the system. The pressure and position control problems are formulated with the required performance specifications. Then, both the pressure and position controller are synthesized using pole placement with sensitivity function shaping techniques. With high bandwidth inner pressure loops, a MIMO triangular controller is designed to control the positions and rotation of the wafer in plane. Moreover, a repetitive control scheme is adopted to enhance the tracking performance of the translational DoFs. Performances of both the MIMO triangular controller and repetitive controller are evaluated experimentally.Delft Center for Systems and ControlMechanical, Maritime and Materials Engineerin
Two-station measurement of Rayleigh-wave phase velocities for the Huatung basin, the westernmost Philippine Sea, with OBS : implications for regional tectonics
No full textAuthor Posting. © The Authors, 2009. This article is posted here by permission of John Wiley & Sons for personal use, not for redistribution. The definitive version was published in Geophysical Journal International 179 (2009): 1859-1869, doi:10.1111/j.1365-246X.2009.04391.x.A broad-band ocean-bottom seismometer (OBS) deployed ~180 km east of Taiwan provides a first glimpse into the upper mantle beneath the westernmost section of the Philippine Sea or the Huatung basin (HB). We measured interstation phase velocities of Rayleigh waves between the OBS and stations on the eastern coast of Taiwan. The phase velocities show smooth variations from 3.8 to 3.9 km s−1 for periods of 25–40 s. In this short period range, phase velocities are comparable to those characterizing the 15–30 Ma Parece-Vela basin of the Philippine Sea. Modelling of the finite-frequency effect proves the validity of the measurement for the average HB. The shear-wave velocity models inverted from the 25 to 40 s dispersion show a velocity at lithospheric depths about 0.1 km s−1 lower than that of the west Philippine Sea, which agrees with the age effect derived from the Pacific pure-path model. Inversions incorporating the less reliable data above 40 s yield a shear velocity <4.0 km s−1 below 150 km, an unrealistic value even for a hotspot plume environment. The seismological evidence, together with the correlation in seafloor depth, suggests that the HB and the Parece-Vela basin may have a similar age. This is at odds with the previous geochronological study suggesting an early-Cretaceous age for the HB. Thermal rejuvenation of the lithosphere was examined as a potential solution to reconciling the two age models.The research is supported by the National
Science Council, Taiwan, Republic of China, under grant NSC
96–2745-M-001–005
Genetically encoding ε-N-methacryllysine into proteins in live cells
No full textThis is an open access article under the CC BY license.Lysine acylation is a ubiquitous post-translational modification (PTM) that plays pivotal roles in various cellular processes, such as transcription, metabolism, protein localization and folding. Thousands of lysine acylation sites have been identified based on advances in antibody enrichment strategies, highly sensitive analysis by mass spectrometry (MS), and bioinformatics. However, only 27 lysine methacrylation (Kmea) sites have been identified exclusively in histone proteins. It is hard to separate, purify and differentiate the Kmea modification from its structural isomer lysine crotonylation (Kcr) using general biochemical approaches. Here, we identify Kmea sites on a non-histone protein, Cyclophillin A (CypA). To investigate the functions of Kmea in CypA, we develop a general genetic code expansion approach to incorporate a non-canonical amino acid (ncAA) ε-N-Methacryllysine (MeaK) into target proteins and identify interacting proteins of methacrylated CypA using affinity-purification MS. We find that Kmea at CypA site 125 regulates cellular redox homeostasis, and HDAC1 is the regulator of Kmea on CypA. Moreover, we discover that genetically encode Kmea can be further methylated to ε-N-methyl-ε-N-methacrylation (Kmemea) in live cells. © The Author(s) 2025.Zhejiang University, ZJU; Life Sciences Institute, LSI; outstanding youth fund of Zhejiang Province, (LR20B050001); Chinesisch-Deutsche Zentrum für Wissenschaftsförderung, CDZ, (C-0023); Chinesisch-Deutsche Zentrum für Wissenschaftsförderung, CDZ; National Key Research and Development Program of China, NKRDPC, (2022YFF0608402); National Key Research and Development Program of China, NKRDPC; State Key Laboratory of Robotics, (SKLPO201806); State Key Laboratory of Robotics; Chinese National Natural Science Funds, (22374128, 91953103, 22074132)We thank technical assistance from LSI core facility, Life Sciences Institute (LSI), Zhejiang University. This work was supported by the Chinese National Natural Science Funds (22374128, 22074132 and 91953103 to B.Y.), the National Key R&D Program of China (2022YFF0608402 to B.Y.), the outstanding youth fund of Zhejiang Province (LR20B050001 to B.Y.), the special COVID-19 program of the Sino-German Center for Research Promotion (C-0023 to B.Y.), Open Project Program of the State Key Laboratory of Proteomics (SKLPO201806 to B.Y.)
John Osborne\u27s Play Luther: A New Discourse in Existentialism
No full textThis paper aims at exploring the presence of existentialist contents in the play Luther (1961) written by eminent litterateur John Osborne. The play focuses on Martin Luther, the sixteenth-century monk who publicly spoke out against age-old practices and beliefs of the Roman Catholic Church thus become one of the foremost instigators of the Protestant Reformation. The drama has a historical setting and a timeless theme. The present paper explores the basic concepts of existentialism, its emergence and how it has dominated various literary works over the years. The paper then makes an in-depth analysis of Luther to understand the various literary techniques employed by the author to express his existentialist theme in the work. It has been found that among the most essential techniques that the author has used include settings, thematic concern, various symbols and motifs and dialogues
- …
