1,721,209 research outputs found
Generation of Gamma-Ray Streaming Kernels Through Cylindrical Ducts via Monte Carlo Method
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Stability Analysis of An Accelerator-Deiven Subcritical Fluid-Fueled Reactor System for Radioactive Waste Transmutation
No full textWeighted Distance Measure for undersampled Signals With higher-Order Multi-Layer Neural Networks
No full textComparative Analysis of Static and Kinetic Calculational Features in the Analytic Function Expansion Nodal Method
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Acceleration of Three-Dimensional AFEN Nodal Codes via Coarse Group Rebalance and Direct Matrix Inverse
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Thermal conductivity of a Jurkat cell measured by a transient laser point heating method
No full textTo understand and quantify the thermal energy transfer in a biological cell, the measurement of thermal properties at a cellular level is emerging as great importance. We report herein a unique technique that utilizes a laser point heat source for temporal temperature rise in a micro-pipette thermal sensor; this technique characterizes heat conduction of a measured sample, the Jurkat cell, thus measuring the sample's thermal conductivity (TC). To this end, we incorporated the computational model in COMSOL to solve for the transient temperature and used the multi-parameter fitting of the experimental data using MATLAB. To address the influence of a Jurkat cell's chemical composition on TC, we compared three structural models for prediction of effective thermal conductivity in heterogeneous materials thereby determining the weight percentage of the Jurkat cell. When considering water and protein as the major constituents, we found that a combination of Maxwell-Euken and Effective Medium Theory modeling provides the closest approximation to published weight percent data and, therefore, is recommended for prediction of the cell composition. We validate the accuracy of the measurement technique, itself, by measuring polyethylene microspheres and observed 1% deviation from published data. The unique technique was determined to be mechanically non-invasive, capable of maintaining viable cells, and capable of measuring the thermal conductivity of a Jurkat cell, which was demonstrated to be 0.538 W/(m.K) +/- 1%. (C) 2020 Elsevier Ltd. All rights reserved.11Nsciescopu
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