1,720,964 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Studies toward the Total Synthesis of the Lapidilectine family of Natural Products via C to N to C Chirality Transfer

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    학위논문(석사)--서울대학교 대학원 :약학대학 약학과,2020. 2. 김상희.Lapidilectine family of natural products is one of the Kopsia alkaloids and contains lapidilectines and grandilodines. They have been isolated from Kopsia lapidilecta and grandifolia, which are distributed over peninsular Malaysia. These include four chiral carbon centers and pyrroloazocine indole core. Among them, lapidilectine B, grandilodine C have remarkable multidrug resistance (MDR) reversing effects. Many research groups have studied synthesis of these attractive targets owing to the unique structures and interesting biological activities. We developed the synthesis of key-intermediate which has pyrroloazocine indole skeleton via new method. An efficient strategy for the asymmetric synthesis has been established. We applied C to N to C chirality transfer strategy through intramolecular Nquaternization and [2,3]-Stevens rearrangement and observed stereoselectivity in the chiral centers. The diastereomeric ratio of key-intermediate was completely transferred to enantiomeric ratio over two steps. These studies toward the total synthesis of Lapidilectine family are expected to lead to important tools for biological research.Lapidilectine family는 lapidilectine과 grandilodine 그룹이 속해 있는 Kopsia 알칼로이드 천연물이다. 말레이 반도의 Kopsia lapidilecta, grandifolia 식물로부터 분리된 인돌 알칼로이드 이며 pyrroloazocine core 와 4개의 카이랄 중심을 포함하고 있다. 이러한 구조적 특이성으로 인해 합성 연구를 위한 흥미로운 천연물로 여겨져 왔다. 생물학적 활성은 vincristine-내성 암세포에서 다중 약물 내성을 극복하는 것으로 알려져 있다. 본 연구에서는 azocino-인돌 골격을 가진 핵심 중간체를 기존과는 다른 새로운 방법을 통해 입체 선택적으로 합성하기 위해 실험을 진행하였다. Key-step에서 N-quaternization 과 [2,3]-Stevens rearrangement 반응을 통해 입체화학 선택적인 카이랄 중심을 도입하였다. 핵심 중간체의 diastereomeric ratio가 2단계의 반응을 통해 얻은 생성물의 enantiomeric ratio로 이어지는 것을 입증하였다. 출발물질로부터 12단계의 반응 중간체까지 7%의 수득률로 얻어냈으며 이후 최종 lapidilectine family의 천연물 합성을 목표로 연구하고 있다. 위의 천연물 합성은 생물학적 연구를 위한 Kopsia 알칼로이드의 다량 제조를 가능하게 할 것으로 기대된다.Introduction 1 Results and Discussion 3 Conclusion 10 Experimental Section 11 References 22 Spectrum Data 24Maste
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