34 research outputs found
Free space broad-bandwidth tunable laser diode based on Littman configuration for 3D profile measurement
No full textOptical thin film inspection using parallel spectral domain optical coherence tomography
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3D Surgical Microscope Based on Optical Coherence Tomography for Microsurgery on the Brain
No full textBiocompatibility evaluation of bioprinted decellularized collagen sheet implanted in vivo cornea using swept-source optical coherence tomography
Get PDFCorneal transplantation by full-thickness penetrating keratoplasty with human donor tissue is a widely accepted treatment for damaged or diseased corneas. Although corneal transplantation has a high success rate, a shortage of high-quality donor tissue is a considerable limitation. Therefore, bioengineered corneas could be an effective solution for this limitation, and a decellularized extracellular matrix comprises a promising scaffold for their fabrication. In this study, three-dimensional bioprinted decellularized collagen sheets were implanted into the stromal layer of the cornea of five rabbits. We performed in vivo noninvasive monitoring of the rabbit corneas using swept-source optical coherence tomography (OCT) after implanting the collagen sheets. Anterior segment OCT images and averaged amplitude-scans were acquired biweekly to monitor corneal thickness after implantation for 1 month. The averaged cornea thickness in the control images was 430.3 +/- 5.9 mu m, while the averaged thickness after corneal implantation was 598.5 +/- 11.8 mu m and 564.5 +/- 12.5 mu m at 2 and 4 weeks, respectively. The corneal thickness reduction of 34 mu m confirmed the biocompatibility through the image analysis of the depth-intensity profile base. Moreover, hematoxylin and eosin staining supported the biocompatibility evaluation of the bioprinted decellularized collagen sheet implantation. Hence, the developed bioprinted decellularized collagen sheets could become an alternative solution to human corneal donor tissue, and the proposed image analysis procedure could be beneficial to confirm the success of the surgery.11Ysciescopu
Industrial resin inspection for display production using automated fluid-inspection based on multimodal optical detection techniques
No full textFull-Field Optical Coherence Tomography Using Galvo Filter-Based Wavelength Swept Laser
No full textWe report a wavelength swept laser-based full-field optical coherence tomography for measuring the surfaces and thicknesses of refractive and reflective samples. The system consists of a galvo filter–based wavelength swept laser and a simple Michelson interferometer. Combinations of the reflective and refractive samples are used to demonstrate the performance of the system. By synchronizing the camera with the source, the cross-sectional information of the samples can be seen after each sweep of the swept source. This system can be effective for the thickness measurement of optical thin films as well as for the depth investigation of samples in industrial applications. A resolution target with a glass cover slip and a step height standard target are imaged, showing the cross-sectional and topographical information of the samples
Quality assessment of the optical thin films using line field spectral domain optical coherence tomography
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