57 research outputs found
The Association of Postoperative Anemia with Adverse Outcomes in Patients Undergoing Cardiac Surgery: A Retrospective Cohort Study
No full textAnemia is a common blood disorder in cardiac surgery patients. While many studies demonstrated a relationship between preoperative anemia and adverse outcomes, few have explored postoperative anemia in this manner. This single-centre retrospective cohort study included 4608 elective cardiac surgery patients and was undertaken to assess the prevalence of postoperative anemia, to identify potential risk factors, and to examine the influence of postoperative anemia on outcomes. Nearly half (48%) of patients developed postoperative anemia. Significant risk factors were female sex, older age, lower BMI, preoperative anemia, poor kidney function, unstable cardiac symptoms, and longer procedure times. Postoperative anemia was a significant predictor of acute kidney injury (odds ratio 1.41; 95% CI 1.09-1.82) and longer hospital stay (ratio of means 1.04; 95% CI 1.00-1.08). The data suggest that postoperative anemia is a highly prevalent and important risk factor for adverse events in cardiac surgery. Therefore, research into potential therapies is necessary.M.Sc
Should all patients having elective first-time coronary bypass grafting surgery be crossmatched for blood?
No full textgrantor:
University of TorontoCurrently blood is reserved (crossmatched) for all patients having coronary artery bypass grafting (CABG) surgery. Many patients, however, will not require any blood and are therefore unnecessarily crossmatched. This practice reduces the general pool of blood in blood banks, increases costs, and leads to wastage of blood. In this study, a clinical prediction rule was developed on 737 patients having elective first- time CABG surgery that allows physicians to predict which patients will need blood during surgery, and only crossmatch blood for these patients. The rule includes four commonly available preoperative patient variables: preoperative haemoglobin, weight, age, and sex. The rule, which was validated on another 296 patients, is accurate (sensitivity = 87.4%, specificity = 57.8%), and should perform well on other patient populations. Application of this rule will eliminate crossmatching in about 50% of patients having elective first-time CABG surgery.M.Sc
Should all patients having elective first-time coronary bypass grafting surgery be crossmatched for blood?
No full textgrantor:
University of TorontoCurrently blood is reserved (crossmatched) for all patients having coronary artery bypass grafting (CABG) surgery. Many patients, however, will not require any blood and are therefore unnecessarily crossmatched. This practice reduces the general pool of blood in blood banks, increases costs, and leads to wastage of blood. In this study, a clinical prediction rule was developed on 737 patients having elective first- time CABG surgery that allows physicians to predict which patients will need blood during surgery, and only crossmatch blood for these patients. The rule includes four commonly available preoperative patient variables: preoperative haemoglobin, weight, age, and sex. The rule, which was validated on another 296 patients, is accurate (sensitivity = 87.4%, specificity = 57.8%), and should perform well on other patient populations. Application of this rule will eliminate crossmatching in about 50% of patients having elective first-time CABG surgery.M.Sc
In reply: Use of early postoperative serum creatinine elevation to identify acute kidney injury after cardiac surgery
No full textCon: Aprotinin Has a Good Efficacy and Safety Profile Relative to Other Alternatives for Prevention of Bleeding in Cardiac Surgery
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