10,932 research outputs found
Will biological agents supplant systemic glucocorticoids as the first-line treatment for thyroid-associated ophthalmopathy?
No full textIn this article, the two authors present their opposing points of view concerning the likelihood that glucocorticoids will be replaced by newly developed biological agents in the treatment of active, moderate-to-severe thyroid-associated ophthalmopathy (TAO). TAO is a vexing, disfiguring and potentially blinding autoimmune manifestation of thyroid autoimmunity. One author expresses the opinion that steroids are nonspecific, frequently fail to improve the disease and can cause sometimes serious side effects. He suggests that glucocorticoids should be replaced as soon as possible by more specific and safer drugs, once they become available. The most promising of these are biological agents. The other author argues that glucocorticoids are proven effective and are unlikely to be replaced by biologicals. He reasons that while they may not uniformly result in optimal benefit, they have been proven effective in many reports. He remains open minded about alternative therapies such as biologicals but remains skeptical that they will replace steroids as the first-line therapy for active, moderate-to-severe TAO without head-to-head comparative clinical trials demonstrating superiority. Despite these very different points of view, both authors are optimistic about the availability of improved medical therapies for TAO, either as single agents or in combination. Further, both agree that better treatment options are needed to improve the care of our patients with active moderate-to-severe TAO
The value of silence
No full textThis is an electronic version of the article published in Theatre Journal, 54(1):85-94, 2002 March. The published article is available at http://muse.jhu.edu/journals/theatre_journal/v054/54.1eng.pdfEng, David L.The Value of Silence.Theatre Journal, 54,(1):85-94, 2002.DOI: 10.1353/tj.2002.000
Sponsorship of TJ Spartak Čelákovice
No full textTitle: Sponsorship of TJ Spartak Čelákovice Objectives: The main objective of this work is to create suitable offer by TJ Spartak Čelákovice for sponsors. We will use this offer, look for the strengths and weaknesses and modify the offer in the process. Methods: First Method will be searching documents important for creating the offer and their analysis. Then we will use the information to create the offer, we will choose communication strategy. We will evaluate the offer, find out its strengths and weaknesses. Results: We found out strengths and weaknesses of our sponsor offer thanks to a year activity looking for sponsors. We also found out, that communication and first contact is very important. Key words: Sponsoring, nohejbal, communication, sponsor offer, amateur spor
Political inertia on higher education and questions for a public inquiry
No full textThis study reviews the media discussion of tertiary education during and after the 2016 federal election. It identifies a series of key questions which went largely unanswered by politicians. Supported by comments from fellow Research Associates of the TJ Ryan Foundation, Scott argues that there is a role for a wide-ranging public inquiry as a basis for establishing an ongoing independent authority to safeguard the wider public interest. This needs to be broader in scope than the current federal government review of funding options
Researching cybercrimes: methodologies, ethics and critical approaches
No full textThis edited book promotes and facilitates cybercrime research by providing a cutting-edge collection of perspectives on the critical usage of online data across platforms, as well as the implementation of both traditional and innovative analysis methods. The accessibility, variety and wealth of data available online presents substantial opportunities for researchers from different disciplines to study cybercrimes and, more generally, human behavior in cyberspace. The unique and dynamic characteristics of cyberspace often demand cross-disciplinary and cross-national research endeavors, but disciplinary, cultural and legal differences can hinder the ability of researchers to collaborate. This work also provides a review of the ethics associated with the use of online data sources across the globe. The authors are drawn from multiple disciplines and nations, providing unique insights into the value and challenges evident in online data use for cybercrime scholarship. It is a key text for researchers at the upper undergraduate level and above
Improvement of formability for the incremental sheet metal forming process
No full textIn order to obtain competitiveness in the held of industrial manufacture, a reduction in the development period for the small batch manufacture of products is required. In order to meet these requirements, an incremental sheet metal forming process has been developed. In this process, a small local region of a sheet blank deforms incrementally by moving a hemispherical head tool over an arbitrary surface. In this work, an incremental sheet metal forming process controlled three dimensionally by a computer has been accomplished. It has been shown by the experiments that a sheet blank is mainly subject to shear-dominant deformation. Therefore, the final thickness strain can be predicted. The uniformity of thickness throughout the deformed region is one of the key factors to improve the formability in the sheet metal forming processes. Using the predicted thickness strain distribution, the intermediate geometry is decided in the manner that a shear deformation is restrained in the highly shear-deformed region and vice versa. This double-pass forming method is found to be very effective so that the thickness strain distribution of a final shape can be made more uniform. (C) 2000 Elsevier Science Ltd. All rights reserved
Visitor Satisfaction at PAS TJ Grape Plantation Agrotourism in Singkawang
No full textBackground: PAS TJ Grape Plantation Agrotourism analyses visitor satisfaction to improve services and attract more visitors.Purpose: This research analyses visitor satisfaction levels at PAS TJ Grape Plantation Agrotourism in Singkawang. By utilising the 7A+1S framework (attraction, amenities, Ancillary services, activity, accessibility, available package, accommodation, and sustainability), this research evaluates the factors influencing visitor experiences. The findings are expected to provide recommendations for managers to enhance service quality and the attractiveness of agrotourism, thereby supporting sustainable agrotourism.Design/methodology/approach: This research employs a nonprobability sampling method with a purposive sampling technique on 40 respondents. Data were collected through structured questionnaires and analysed using descriptive statistical methods. Validity and reliability tests were conducted, along with the Customer Satisfaction Index (CSI) and Importance-Performance Analysis (IPA), to assess visitor satisfaction and service performance.Findings/result: Based on the Customer Satisfaction Index (CSI) and Importance Performance Analysis (IPA), visitor satisfaction at PAS TJ Grape Plantation reached 81.22%, categorised as "very satisfied." While visitors generally have a positive experience, some aspects need improvement. The IPA results highlight the availability of a canteen, road conditions, and supporting infrastructure as key concerns, as they are essential but underperforming. Meanwhile, other attributes meet or exceed expectations. Addressing these gaps, particularly those in Quadrant I (high importance, low performance), is crucial for enhancing visitor satisfaction.Conclusion: Overall, the attributes of PAS TJ Grape Plantation agrotourism in Singkawang are very satisfying for visitors. However, improvements in facilities and infrastructure are needed to enhance visitor satisfaction and attract more visitors in the future.Originality/value (State of the art): This research contributes to developing a visitor satisfaction analysis methodology by applying the 7A+1S approach, which has not been widely used in agritourism. Focusing on PAS TJ Grape Plantation Agrotourism, this research is expected to serve as a reference for developing sustainable agritourism in other regions.
Keywords: Visitor satisfaction, Agrotourism, Customer satisfaction index (CSI), and Importance performance analysis (IPA
TJ-ACA: An Advanced Cryptographic Algorithm forColor Images using
No full textABSTRACT-Presently, cryptography of images is of high concern due to highly confidential information contained in it. Image encryption is difficult as compared to text encryption because of high correlation among pixels and bulk information capacity. A newly proposed algorithm based on symmetric key algorithm, TJ-ACA, an advanced cryptographic algorithm will make use of pixel position alteration, and pixel intensity surrogation through which a visually changed image i.e. encrypted image is obtained. In this algorithm, ikeda mapping and various methods are used to get highly secure image. To increase the security ikeda mapping is done at five different values instead of single value. This proposed algorithm is applicable for color images and also for images on which steganography has been applied and by this method we get lossless decrypted image. This method resists Brute Force attack. TJ-ACA can be applied to all sizes images which can be used in medical, aerial application
Marketing Communication of Handball Club TJ Sokol Praha Vršovice
No full textTitle: Marketing Communication of Handball Club TJ Sokol Praha Vršovice Objectives: The main aim of this bachelor thesis was to create a proposal for a new concept of marketing communication for the sports club TJ Sokol Praha Vršovice, focused on one of its main current problems which is the dimension and structure of the members' basement. In connection with that, it was necessary to do marketing research to find out the conditions and actual situation in using current tools of marketing communication by the sports club. Methods: Both methods of analysis, qualitative (interview) and quantitative (written survey), were used. Results: Data acquired from analysis was utilized and summarised in the results section. The proposal for a new concept of marketing communication was created on the basis of these results. Key words: Marketing communication, enrolment of members, sports club, handbal
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