32 research outputs found
Storage sharing at import dry-bulk terminals: A case study at Gadani Energy Park
The Gadani Energy Park is a to-be build project in which ten coal-fired power plants are established at one location near the shore of Karachi, Pakistan. In the initial situation, all power plants manage their own on-shore operations. The objective of this study is to gain insight in the advantages and disadvantages of yard collaboration in bulk environments, by using the Gadani Energy Park as an example. The expected benefits gained by collaboration have to be distributed fairly to encourage owners to participate. This is done by using the Shapley value, which proves to provide a feasible cost allocation structure.Transport Engineering and LogisticsMarine and Transport TechnologyMechanical, Maritime and Materials Engineerin
Studies on structural and electrical properties of nanostructured RMnO3 (R = Gd & Ho)
Effect of vanadium substitution on structural and electrical properties of sol–gel grown nanostructured zinc oxide
Mechanism of Anti-bacterial Activity of Zinc Oxide Nanoparticle Against Carbapenem-Resistant Acinetobacter baumannii
Mechanism of Anti-bacterial Activity of Zinc Oxide Nanoparticle Against Carbapenem-Resistant Acinetobacter baumannii
Acinetobacter baumannii is a multi-drug resistant opportunistic pathogen, which causes respiratory and urinary tract infections. Its prevalence increases gradually in the clinical setup. Carbapenems (beta-lactam) are most effective antibiotics till now against A. baumannii, but the development of resistance against it may lead to high mortality. Therefore, it is of utmost importance to develop an alternative drug against A. baumannii. In the present study, we have synthesized ZnO nanoparticle (ZnO-NP) and characterized by X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy and UV-Visible spectroscopy. Prepared ZnO-NPs have the size of 30 nm and have different characteristics of ZnO-NPs. Growth kinetics and disk diffusion assay showed that ZnO-NP demonstrated good antibacterial activity against carbapenem resistant A. baumannii. We have also investigated the mechanism of action of ZnO-NPs on the carbapenem resistant strain of A. baumannii. The proposed mechanism of action of ZnO involves the production of reactive oxygen species, which elevates membrane lipid peroxidation that causes membrane leakage of reducing sugars, DNA, proteins, and reduces cell viability. These results demonstrate that ZnO-NP could be developed as alternative therapeutics against A. baumannii
