1,471 research outputs found

    Dr. Shanesha R.F. Brooks-Tatum, RWWL AUC, July 2011

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    This video is a conversation with Dr. Shanesha R.F. Brooks-Tatum. Dr. Brooks-Tatum talks about her book, "The Encyclopedia of Hip Hop Literature." Daniel Le, AUC Woodruff Library, is the interviewer

    Letter: R.F. Pettigrew to H.L. Loucks, May 30, 1916

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    R.F. Pettigrew articulates to H.L. Loucks his distaste for the book that Loucks recommended to him. Pettigrew also mentions that he would prefer to remain distanced from any conference with the author of the book. Pettigrew expresses great admiration and interest in Loucks' manuscript and desire to read it further

    The evolution of fat grafting : from soft tissue augmentation to regenerative medicine

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    The Author traces the evolution of fat grafting over the years from the first publication in 1893, to the systematization of the technique thanks to the contribution of Sydney Coleman. In recent years studies on the nature of adipose tissue have shown that besides multiple resident cells, fat tissue contains stem cells (ADSCs) capable of differentiating in multiple lineages, such as bone, cartilage, muscle, nerve, etc. Thus, in addition to the traditional notion that fat is a high energy reservoir, it becomes apparent that fat is a repair organ providing the basis for soft tissue regeneration. Manipulation of ADSCs promises to affect different fields of medicine and provide the physician with a variety of regenerative medical therapies

    RNA interference, growth and differentiation appear normal in African trypanosomes lacking Tudor staphylococcal nuclease.

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    Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease converts double-stranded (ds)RNA into small interfering (si)RNA and the Slicer endonuclease, as a component of the RNA induced silencing complex (RISC), cleaves mRNA. Tudor staphylococcal nuclease (Tudor-SN) is another component of RISC in humans, flies and nematodes and is therefore implicated in the RNAi pathway. Here, we explore the potential role of African trypanosome Tudor-SN in RNAi. First, we assembled tudor-sn null mutants and showed that the gene is dispensable for normal growth and for differentiation. Next, we developed an inducible RNAi reporter system and demonstrated that Tudor-SN is dispensable for RNAi. The kinetics of mRNA knock-down, protein knock-down and protein recovery following inactivation of dsRNA expression are all unperturbed in the absence of Tudor-SN. We conclude that if this nuclease plays a role in the destruction or processing of dsRNA, mRNA or siRNA in the RNAi pathway, it is likely a minor one

    Low-frequency model-order reduction of electromagnetic fields without matrix factorization

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    Electrical Engineering, Mathematics and Computer Scienc

    In memory of Paul Tessier, MD (1917-2008)

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    The Author traces the life and the surgical achievements of Paul Tessier, founder of craniofacial surgery

    Old and new in fat grafting

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    The author traces the evolution of fat grafting over the years and shows the potential clinical applications in the different areas of the body

    Presentazione

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    The Author traces the evolution of Aesthetic Rhinoplasty in Italy from the first contribution published by G. Sanvenero Rosselli in 1931

    Semiconserved regulation of mesendoderm differentiation by microRNAs.

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    MicroRNAs are known to play important roles in many different processes. However, their roles in shaping the early steps in embryogenesis have remained largely hidden. In this issue of Developmental Cell, Rosa et al. show that the miR-430/427/302 family of microRNAs has a distinct effect on Nodal signaling, affecting mesendoderm differentiation in Xenopus embryos and human embryonic cell lines.

    MicroRNA Biogenesis and Function: An overview

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    In: Regulation of microRNAs Ed: H Grosshans Landes Bioscience and Springer.
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