10,633 research outputs found

    DACB author spotlight: Dr. Michael Adeleke Ogunewu

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    [I would like to take this opportunity to honor the legacy of one of the DACB’s exceptionally prolific authors and educators, Michael Adeleke Ogunewu, described here, in the draft of a 2015 article I wrote for Orita:....

    Synthesis and biological activity of allosteric modulators of GABA(B) receptors, Part 2. 3-(2,6-bis-tert-butyl-4-hydroxyphenyl)propanols

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    A series of 13 2,2-disubstituted 3-(3,5-di-t-butyl-4-hydroxyphenyl)propan-1-ol derivatives have been prepared for evaluation as allosteric modulators of GABAB receptors. The activity (EC50, 4–7 μM) was greatest for the cyclohexyl and cyclopentyl analogues.David I. B. Kerr, Jabbar Khalafy, Jennifer Ong, Michael V. Perkins, Rolf H. Prager, Ni Made Puspawati and Mehdi Rima

    The digital search for meaning: an interview with Michael Maguire

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    I met and spoke with Michael J. Maguire, one of Ireland’s most prominent—if not the most prominent—author of electronic literature

    Michael Strunge

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    Short presentation of danish author Michael Strunge and his main work

    Poverty, the U.S. South, and the SRSA

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    This paper is a broad expansion of an SRSA Research Fellows Address presented in Roslyn, Virginia on April 16th, 2019. In it, I extol the virtues of poverty research, particularly that focused on the U.S. where households living on less than $4/day/person compose the largest shares of county populations. I note that two factors that are the hallmark of such extreme poverty-- lack of a vehicle and lack of internet service --are forcing poor household to perceive themselves as ever more isolated, for greater accessibility for the rest of the U.S. population amplifies the gap created by their deficiency. This is because others expect everyone has such access. Southern areas with persistent poverty --the Black Belt, the Mississippi Delta, and Appalachia --have concentrations of such extreme poor and also have deficient access to the rest of the world. I suggest that Americans should find a way to ameliorate this condition. I conclude by encouraging my SRSA colleagues to do what they do best, but with a poverty tilt, as a means of petitioning policy makers and the public.Peer reviewe

    Regional Input-Output Analysis: An Appraisal of an Imperfect World

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    In the last retrospective on regional input-output analysis, Hewings and Jensen (1988) set out a set of emerging challenges. This paper generally examines how those challenges have been met in the intervening 25 years (plus some). A feature of this endeavor is to help young scholars identify research directions. In this vein, along the way I point out avenues that could be pursued. I conclude by identifying topics in input-output analysis that are currently hot and those that are not

    Poverty, the U.S. South, and the SRSA

    No full text
    This paper is a broad expansion of an SRSA Research Fellows Address presented in Roslyn, Virginia on April 16th, 2019. In it, I extol the virtues of poverty research, particularly that focused on the U.S. where households living on less than $4/day/person compose the largest shares of county populations. I note that two factors that are the hallmark of such extreme poverty-- lack of a vehicle and lack of internet service --are forcing poor household to perceive themselves as ever more isolated, for greater accessibility for the rest of the U.S. population amplifies the gap created by their deficiency. This is because others expect everyone has such access. Southern areas with persistent poverty --the Black Belt, the Mississippi Delta, and Appalachia --have concentrations of such extreme poor and also have deficient access to the rest of the world. I suggest that Americans should find a way to ameliorate this condition. I conclude by encouraging my SRSA colleagues to do what they do best, but with a poverty tilt, as a means of petitioning policy makers and the public.Peer reviewe

    Poverty, the U.S. South, and the SRSA

    No full text
    This paper is a broad expansion of an SRSA Research Fellows Address presented in Roslyn, Virginia on April 16th, 2019. In it, I extol the virtues of poverty research, particularly that focused on the U.S. where households living on less than $4/day/person compose the largest shares of county populations. I note that two factors that are the hallmark of such extreme poverty-- lack of a vehicle and lack of internet service --are forcing poor household to perceive themselves as ever more isolated, for greater accessibility for the rest of the U.S. population amplifies the gap created by their deficiency. This is because others expect everyone has such access. Southern areas with persistent poverty --the Black Belt, the Mississippi Delta, and Appalachia --have concentrations of such extreme poor and also have deficient access to the rest of the world. I suggest that Americans should find a way to ameliorate this condition. I conclude by encouraging my SRSA colleagues to do what they do best, but with a poverty tilt, as a means of petitioning policy makers and the public

    A study of the systematic risks of New Jersey’s casinos: phase I - the market saturation point and NJ’s share

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    This is the first-phase report. In this phase of reporting, we examine the pattern of regional casino gross gaming revenues (GGR) in Atlantic City (AC) and its regional market alongside its relationship to aggregate regional personal income. To give a sense of competition to New Jersey’s (NJ) casinos in the market place, we review the chronology of casino openings and closings both in NJ and nearby in other states. This enables us to ascertain their effects upon regionwide and AC net gaming revenues as well as on casino survival. The main new finding in this report is that there has been relatively little variation over time in the ratio of regional GGR to aggregate regional personal income. Interestingly, this ratio tends to vary between 0.45 and 0.50%, which suggests that the area market for gaming has been saturated. And the main story of the past twelve years, which is rather well known, has been that the successful rise of casinos in eastern Pennsylvania has been at the expense of NJ’s casinos, which had cornered the market prior to 1996. In 2018, NJ’s casinos maintained only about 26.1% of all area GGR. The current (2018) ratio of regional GGR to aggregate personal income is well below its 2013 peak (0.514%) and sits close to its long-term average (0.477%). This indicates either there could be modest room for expansion in the region or that distant markets—like Las Vegas, Monaco, and Macao—have slowly been absorbing more of what used to be a localized market base. Recent data show that last year’s opening of two new casinos in AC seems to have enhanced overall gross gaming revenues for NJ. This marked the first net gains in gross gaming revenue in AC since 2007! Unfortunately, these same two casinos seem to have benefited by cannibalizing from the existing set of AC casinos, all of which experienced GGR declines. Of course, these declines could also be partly attributed to the introduction of sports betting. In the next phase of reporting, we will continue to investigate what drives changes in regional GGR, its relationship to regional income, and the implications for casino viability in AC. In particular, we will investigate the potential causes of variation over time in the ratio of regional GGR to aggregate regional personal income since this appears to be a critical parameter. We will also identify more precisely the sensitivity of gross gaming revenues at NJ casinos to casinos entering in New York City and in Philadelphia. We will also investigate the likely implications of adding one or more new casinos in AC
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