1,259 research outputs found
A missense mutation in the vacuolar protein GOLD36 causes organizational defects in the ER and aberrant protein trafficking in the plant secretory pathway
A missense mutation in the arabidopsis copii coat protein sec24a induces the formation of clusters of the endoplasmic reticulum and golgi apparatus
How the endoplasmic reticulum (ER) and the Golgi apparatus maintain their morphological and functional identity while working in concert to ensure the production of biomolecules necessary for the cell's survival is a fundamental question in plant biology. Here, we isolated and characterized an Arabidopsis thaliana mutant that partially accumulates Golgi membrane markers and a soluble secretory marker in globular structures composed of a mass of convoluted ER tubules that maintain a connection with the bulk ER. We established that the aberrant phenotype was due to a missense recessive mutation in sec24A, one of the three Arabidopsis isoforms encoding the coat protomer complex II (COPII) protein Sec24, and that the mutation affects the distribution of this critical component at ER export sites. By contrast, total loss of sec24A function was lethal, suggesting that Arabidopsis sec24A is an essential gene. These results produce important insights into the functional diversification of plant COPII coat components and the role of these proteins in maintaining the dynamic identity of organelles of the early plant secretory pathway
Sociology essay
Sociology essay by Jitsuso Tamura for a class assignment at Tri-State High School at Tule Lake incarceration camp. Covers how population influences social life and problems.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Institute for Global Environmental Strategies (IGES) Submission to the Talanoa Dialogue of the UNFCCC
A Revised Second-Order Discretization of The 2-D Elastic Beam Element <i>Masahiro AI, Kentaro TAMURA and Fumio NISHINO</i>
Training Program on Developing Project Proposals on Climate Change Mitigation / 気候変動緩和プロジェクト案策定のためのトレーニングプログラム
Minimizing dose variation from the interplay effect in tereotactic radiation therapy using volumetric modulated arc therapy for lung cancer
学位の種類:医学 学位授与年月日:平成31年3月19日 主査:光冨,徹哉 教授 報告番号:甲第1397号 学内授与番号:医第1282号 Kazuki Kubo, Hajime Monzen, Mikoto Tamura, Makoto Hirata, Kentaro Ishii, Wataru Okada, Ryuta Nakahara, Shun Kishimoto, Ryu Kawamorita, Yasumasa Nishimura, Minimizing dose variation from the interplay effect in stereotactic radiation therapy using volumetric modulated arc therapy for lung cancer, RADIATION ONCOLOGY PHYSICS, 2018, https://doi.org/10.1002/acm2.12264 掲載application/pdfdoctoral thesi
- …
