140 research outputs found
Three essays in applied econometrics
No full textThis dissertation presents three essays which are linked by the use of econometric models to explain problems that are only explained descriptively in the literature. The first essay, statistically shows that a systematic measurement bias can significantly distort predictions obtained using an international accounting framework due to the sizable diversity of the parties involved in it. Once the measurement bias is taken into account, the average value gains on the US foreign asset and liability categories are estimated to be smaller, and no evidence is found on positive yield differential. The second essay estimates the value gains and the mismeasurement using data at multiple frequencies. The results show that positive sizable return differential is present after 2002. The third essay shows that the increasing availability of prescription opioids threatens sellers' profit margin since it is a close substitute for heroin and forces sellers to find alternative methods to compensate buyers in the case of a negative supply shock.Ph.D.Includes bibliographical referencesIncludes vitaby Emel Oylum Yildiri
Synthesis, spectroscopic characterization and DFT calculations of novel Schiff base containing thiophene ring
No full textWOS: 000425075900011In this study, a new Schiff base derivative, 2-[(2-hydroxy-5-thiophen-2-yl-benzylidene)-amino]-6-methyl-benzoic acid (5), which has a thiophene ring and N, O donor groups, was successfully prepared by the condensation reaction of 2-hydroxy-5-(thiophen-2-yl)benzaldehyde (3) and 2-amino-6-methylbenzoic acid (4). The characterization of a Schiff base derivative (5) was performed by experimentally the UV-Vis., FTIR, H-1 and C-13 NMR spectroscopic methods and elemental analysis. Density Functional Theory (DFT/B3LYP/6-311+G(d, p)) calculations were used to examine the optimized molecular geometry, vibrational frequencies, H-1 and C-13 NMR chemical shifts, UV-Vis. spectroscopic parameters, HOMO-LUMO energies and molecular electrostatic potential (MEP) map of the compound (5) and the theoretical results were compared to the experimental data. In addition, the energetic behaviors such as the sum of electronic and thermal free energy (SETFE), atomic charges, dipole moment of the compound (5) in solvent media were investigated using the B3LYP method with the 6-311+G(d, p) basis set. The obtained experimental and theoretical results were found to be compatible with each other and they were supported the proposed molecular structure for the synthesized Schiff base derivative (5)Anadolu University Scientific Research Projects (BAP) [1705F213]; BAP [1102F027, 1304F064]; [1306F110]This study was supported by Anadolu University Scientific Research Projects (BAP) through project 1705F213. The author also gratefully thank to BAP for supporting Gaussian 09 and Gauss View 5.0 programs with the projects (Project No 1102F027 and 1304F064) and its financial support for Agilent DD2 NMR Spectrometer (Project No. 1306F110)
Assessment of implication of competitiveness on human development of countries through data envelopment analysis and cluster analysis
No full textFüsun Ülengin (Dogus Author) -- Özgür Kabak (Dogus Author) -- Şule Önsel (Dogus Author) -- Emel Aktaş (Dogus Author)Globalization speeds up competition among nations in various sectors. In terms of multinational and transnational phenomena, countries are seen as inescapable from competition, thus the linking of the term global with "competitiveness." The research described here explores the relationship between the competitiveness of a country and its implications for human development. For this purpose, using data envelopment analysis (DEA) and cluster analysis, 44 selected countries were evaluated. An output-oriented super-efficiency model where global competitiveness indicators are taken as input variables with human development indicators as output variables is utilized. Then cluster analysis depending on the competitiveness and human development indicators is conducted by using self-organizing maps to specify the development levels of the countries. Both analyses are repeated for years between 2005 and 2007. Finally, the relationship between the super efficiency scores and the development levels is analyzed
Investigation of microplastic pollution in sediment and beach sand samples in the coastal areas of Bursa
No full text18.01.2025 tarihine kadar kullanımı yazar tarafından kısıtlanmıştır.Lisansüstü Eğitim Enstitüsü, Çevre Mühendisliği Ana Bilim Dalı, Çevre Sağlığı Bilim Dalıİnsanların, günümüz dünyasında hızla artan nüfusun ihtiyaçlarını karşılamak için maliyeti düşük ve hızlı çözüm arayışı çevre kirliliğinin artmasındaki en önemli sebeplerinden biridir. Kullanımı ve üretimi gittikçe artan plastikler de, son zamanlarda en önemli çevre sorunlarından biridir. Mikroplastikler, suda çözünmeyen, büyüklüğü 5 mm'den küçük, kalıcı plastik parçacıklar olarak tanımlanmaktadır (Leslie ve diğ. 2017) ve ilk tanımlandığı yıldan itibaren (2004) önemli çevresel kirletici olarak dikkat çekmektedir (Tagg ve diğ. 2017). Bu çalışmada, yaz mevsimi için Ağustos 2022, kış mevsimi için ise Şubat 2023 tarihleri temel alınarak beş farklı istasyonda sediment ve plaj kumu örnekleri alınmış olup fizikokimyasal ve mikroplastik (MP) analiz yapılmıştır. Mikroplastiklerin sayısı, renkleri, boyutları ve tipleri belirlenmiştir. FTIR spektrometresi kullanılarak polimer türleri incelenmiştir. FTIR analizleri sonrasında belirlenen noktalardan alınan numunelerin hepsinde PP, PE, PVC ve PET polimer türlerinin varlığı tespit edilmiştir. Mikroplastikleri belirlemek için yapılan analizler sonucunda yaz mevsimi için 3984 partikül / 1 kg mikroplastik, kış mevsimi için ise 2576 partikül/ 1 kg mikroplastik elde edilmiştir. Çalışmada gözlemlenen mikroplastik beyaz, gri, sarı, turuncu, pembe, kırmızı, yeşil, mavi, mor ve siyah bulunmuştur. Bursa'nın Gemlik ve Mudanya ilçelerinde belirlenen noktalarda yapılan analizler sonucunda mikroplastiklerin mevcut durumu belirlenmiş, kaynakları anlaşılmaya çalışılmış ve olası olumsuz etkilerinin en aza indirilmesi için öneriler sunulmuştur.In today's world, people's search for low-cost and fast solutions to meet the needs of a rapidly growing population is one of the most important reasons for the increase in environmental pollution and plastics are one of the most important environmental problems in recent researches. Plastics from 5 mm to 1 mm are considered microplastics (MP) and it attracts attention as an important environmental pollutant. The aim of this thesis was to investigate the detection and distribution of microplastics in Southern Marmara region, sand beach and sediment samples were taken from 5 different sampling points in the Bursa in August 2022 and February 2023. Microplastics and Physicochemical analyzes were carried out in the laboratory. Extraction and intensive separation were used as a method for microplastic analyzes. The number, colors, sizes and shape of microplastics were studied in the sediment and beach sand samples. In addition to those datas, polymer type were also examined for plastics. FTIR (Fourier transform infrared spectroscopy) spectroscopy was used for polymer type of microplastics. PP, PE, PVC and PET polymer types were found as a result of FTIR analysis. The total accumulation of microplastics in the summer season is 3984 particles / 1 kg of microplastics and 2576 particles / 1 kg of microplastics was obtained for the winter season. White were the most determined colour of microplastic in summer samples while blue were the most determined colour for microplastics in winter samples. Other than white and blue colour of microplastics, samples were contain grey, yellow, orange, pink, red, green, blue, purple and black colours. Samplings were carried out in different seasons and comments were made on the effect of season on pollution. The current status of microplastics has been determined, their sources have been tried to be understood and recommendations have been presented to minimize their possible negative effects
The Analysis of Conceptual Studies On Contemporary Ceramics Art in Light of Peter Osborne's Conceptual Art Initiative
No full textSanat olgusu ortaya çıktığı dönemden günümüze değin yapılan pek çok sanat eseriyle farklı nitelik ve yorumlar kazanarak gelişmiştir. Bu gelişmeler ve dönüşümler sonucunda 20.yüzyılın ikinci yarısından itibaren içerisinde bulunduğumuz dönem postmodern olarak adlandırılmakta ve sanatın sonu şeklinde değerlendirilmektedir.Sanatta yaşanan bu büyük dönüşümler pek çok disiplini olduğu gibi seramik sanatını da etkilemiştir. Seramik sanatı 19.yüzyıl ve sonrası sanayi devriminden sonra gelişen teknoloji ve farklılaşan kültürel yapılarla, 20.yüzyılda sanatsal bir disiplin olarak kabul görmüştür. Bu süreçte çağdaş seramik sanatçılarının yorumlarıyla, kavrama yönelik eserler ortaya konmuştur.Kavramsal Sanat ise temelinde düşüncenin yapıta üstünlüğü fikrini barındıran Postmodern dönem içerisinde büyük bir kırılma yaratmış olan bir eğilimdir. Kavramsal sanat, seramik sanatının evrensel nitelik kazanmasına, geleneksel ve modernist uslüba karşı duran kavramsal seramik eserler üretilmesine olanak sağlaması bakımından seramik sanat tarihinde önemli bir yere sahiptir. Postmodernizmin eklektik yapısıyla birleşen kavramsal seramik eserler çağın gerçekliklerinin kavranmasını kolaylaştırırken, geçmişle bağ kurarak belgesel bir nitelik taşımaktadır. Bu çalışmada, çağdaş seramik sanatında, sanat anlayışında bir dönüm noktası olan kavramsal sanatın önemi ve seramik sanatına katkıları felsefe profesörü ve yazar Peter Osborne'nin kavramsal sanat açılımı doğrultusunda incelenmektedir.Ever since it emerged to present, the art fact has developed by getting different qualities and comments with many art works. As a result of these developments and transformations, the period which we are in since the second half of the 20th century is called Postmodernism and considered to be end of the art These efficient transformations as influenced the ceramic art as many disciplines. In the 20th century, ceramic art has been accepted as an artistic discipline with the 19th century and later by industrial revolution, the developing of technology and differing cultural structures. In this process, conceptual art works were created by contemporary ceramic artists' interpretations. Conceptual art is a trend which created a big break in the postmodern period, which is based on the idea that is thought, has superiority to the art work. In the ceramic art history, conceptual art history has an important place because of enabling of the creating ceramic art works which stands against the traditional and the modernist style. Conceptual ceramic art works, which combine with eclectic nature of postmodernism, has a documentary feature by establishing a link with the past while make it easy to grasp realities of era. In this study, the importance of conception art, which is a milestone in the art conception and its contributions to ceramic art, are examined according to philosophy professor and author Peter Osborne's conceptual art initiative
Metagenomik Alalysis of Environmental Microbial Sources: Case Study of Çal Cave
No full textMetagenomic Analysis Of Environmental Microbial Sources: Case StudyOf Çal CaveHasan Demirci1, Emel Ordu1*1 Department of Molecular Biology and Genetics, Yildiz Technical University, Faculty of Arts and Sciences, ,Turkey*Corresponding Author: [email protected], which constitute the vast majority of life forms in the environment, have animportant usage in the biotechnological fields such as medicine, food, energy, agriculture etc.However, it is known that 1% of these microbial diversity have been identified withtraditional cultivation methods, and a very few of them have been cultured and employed inindustrial purpose. Metagenomics, which is a culture-independent approach, and developmentof next-generation sequencing technologies provide not only a wealth of phylogeneticinformation about the environmental microbial samples but also broaden the microbialresource utilization for industrially important enzyme researches. Caves where representunique environments in terms of microbial flora, are ideal habitats for searching novelmicroorganisms, consequently new enzymes. Çal cave in Trabzon is one of the importantkarstic caves in Turkey. We explored the microbial diversity of Çal cave by metagenomicanalysis in order to understand the potential of genomic sources in terms of new enzymes andbioactive compounds meeting industrial demand. Early results showed that cave soil wasdominated by Actinobacteria and Proteobacteria well known as potential sources of bioactivecompounds.Keywords: Actinobacteria, cave soil, metagenomics, Proteobacteria, taxonomic profiling,Acknowledgements: "This work was supported by Research Fund of the Yildiz TechnicalUniversity. Project Number: FDK-2019-3586 ".</p
Usage of ceramics for birdhouses as a material
No full textThe reason of this research is to study birdhouses which comes through out Ottoman to nowadays as an old Anatolian tradition, to display the changes of Turkish point of view to birdhouse tradition with the changing world and to investigate birdhouses and ceramic artists who works on birdhouses in ceramics art. Besides the history and development of birdhouses which comes from 13th century, birdhouses are investigated which are made in different techniques and different materials and it also investigated that native and foreign ceramics artist and their works who has works about birdhousesŞölenay, Emel, Çelikoğlu, Öncü (Anadolu Author)Bu araştırmanın amacı, Anadolu’da eski bir gelenek olan ve Osmanlı’dan günümüze kadar süregelen kuşevlerini araştırmak, değişen dünya ile beraber kuşevleri geleneğinde Türklerin bakış açılarındaki değişimleri ortaya koymak ve seramik sanatındaki kuşevlerini ve kuşevi üzerine çalışmalar yapan seramik sanatçılarını incelemektir. Geçmişi 13. yüzyıla kadar giden kuşevlerinin tarihi ve gelişiminin yanı sıra, değişik malzemelerle yapılan kuşevleri ve kuşevi yapım teknikleri ve ayrıca kuşevi üzerine eser veren Türk ve yabancı seramik sanatçıları ve bu sanatçıların eserleri incelenmiştir
The Role of Azacitidine in the Treatment of Elderly Patients with Acute Myeloid Leukemia: Results of a Retrospective Multicenter Study
No full textKaynar, Leylagul/0000-0002-2035-9462; GURKAN, EMEL/0000-0002-3060-4054; Sahin, Fahri/0000-0001-9315-8891WOS: 000392282500002PubMed: 27095141Objective: In this study, we aimed to investigate the efficacy and safety of azacitidine (AZA) in elderly patients with acute myeloid leukemia (AML), including patients with >30% bone marrow (BM) blasts. Materials and Methods: In this retrospective multicenter study, 130 patients of >= 60 years old who were ineligible for intensive chemotherapy or had progressed despite conventional treatment were included. Results: The median age was 73 years and 61.5% of patients had >30% BM blasts. Patients received AZA for a median of four cycles (range: 1-21). Initial overall response [including complete remission (CR)/CR with incomplete recovery/partial remission] was 36.2%. Hematologic improvement (HI) of any kind was documented in 37.7% of all patients. HI was also documented in 27.1% of patients who were unresponsive to treatment. Median overall survival (OS) was 18 months for responders and 12 months for nonresponders (p=0.005). In the unresponsive patient group, any HI improved OS compared to patients without any HI (median OS was 14 months versus 10 months, p=0.068). Eastern Cooperative Oncology Group performance status of = 5 courses), and any HI predicted better OS. Age, AML type, and BM blast percentage had no impact. Conclusion: We conclude that AZA is effective and well tolerated in elderly comorbid AML patients, irrespective of BM blast count, and HI should be considered a sufficient response to continue treatment with AZA
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