863 research outputs found
Securitization of Islam: A Vicious Circle
No full textDiverse Islamic groups have triggered a "revival of Islam" in Central Asia in the last decades. As a result, there has been a general securitization of Islam by the governments: not only do they combat the terrorist Islamic Movement of Uzbekistan but also outlaw popular groups such as the Gülen movement. However, strong repression of religion might lead to radicalization. Kathrin Lenz-Raymann tests this hypothesis with an agent-based computer simulation and enriches her study with interviews with international experts, leaders of political Islam and representatives of folk Islam. She concludes that ensuring religious rights is essential for national security
Securitization of Islam: A Vicious Circle; Counter-Terrorism and Freedom of Religion in Central Asia
No full textDiverse Islamic groups have triggered a "revival of Islam" in Central Asia in the last decades. As a result, there has been a general securitization of Islam by the governments: not only do they combat the terrorist Islamic Movement of Uzbekistan but also outlaw popular groups such as the Gülen movement. However, strong repression of religion might lead to radicalization. The author tests this hypothesis with an agent-based computer simulation and enriches her study with interviews with international experts, leaders of political Islam and representatives of folk Islam. She concludes that ensuring religious rights is essential for national security
Repurpsing Antiviral Drugs for Orthogonal RNA-Catalyzed Labeling
No full textIn vitro selected ribozymes are promising tools for site-specific labeling of RNA. Previously known nucleic acid catalysts attached fluorescently labeled adenosine or guanosine derivatives through 2’,5’-branched phosphodiester bonds to the RNA of interest. Herein, we report new ribozymes that use orthogonal substrates, derived from the antiviral drug tenofovir, and attach bioorthogonal functional groups, as well as affinity handles and fluorescent reporter units through a hydrolytically more stable phosphonate ester linkage. The tenofovir transferase ribozymes were identified by in vitro selection and are orthogonal to nucleotide transferase ribozymes. As genetically encodable functional RNAs, these ribozymes may be developed for potential cellular applications. The orthogonal ribozymes addressed desired target sites in large RNAs in vitro, as shown by fluorescent labeling of E. coli 16S and 23S RNAs in total cellular RNA
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