9 research outputs found
Synthesis of α-amino phosphonates catalyzed by bifunctional cyclohexane derived thiourea organocatalyst
No full text183-191Multicomponent phosphonylation is accomplished by convenient and efficient synthetic method using novel (S)-N-
((cyclohexylmethyl) carbamothioyl) pyrrolidine-2-carboxamide (NCCPC) as bifunctional cyclohexane derived thiourea
organocatalyst upon the reaction of an amine, substituted aldehyde with diethyl phosphite. This method not only provides
novel and excellent complement for the synthesis but also gives green and transition-metal-free protocol, shows a broad
substrate scope, providing a variety of α-amino phosphonates in moderate to good yields
Ru(II)/PEG-400: A green synthesis of indolyl-oxindoles and indolyl-cyclohexanedione hybrids as potential antimicrobial agents
No full text107-114A green and sustainable methodology has been successfully employed for the synthesis of 3-Indolyl-3-hydroxy
oxindoles and 3-indolyl-3-hydroxy-5,5-dimethylcyclohexane-1,3-dione derivatives using Ru(II)/PEG-400 as a homogeneous
recyclable catalytic system from substituted isatin with indole and dimedone. Short reaction time, simple extraction
procedure, substrate scope with high yield of the product, biodegradable solvent and recyclability of the catalyst without loss
of its activity enhances the efficiency of the proposed protocol. The synthesized compounds are studied for their
antimicrobial activity
ChemInform Abstract: Synthesis and Molecular Docking Studies of Oxochromenyl Xanthenone and Indolyl Xanthenone Derivatives as anti‐HIV‐1 RT Inhibitors.
No full textChemInform Abstract: Synthesis and Molecular Docking Study of Novel Chromeno‐Chromenones as anti‐HIV‐1 NNRT Inhibitors.
No full textA green synthesis of isoquinolines using Ru(II)/PEG-400 as homogeneous recyclable catalyst via C-H/N-N bond activation
Get PDF842-849A novel and green synthesis of 1-phenyl isoquinoline derivatives has been developed by using Ru(II)/PEG-400 as homogeneous recyclable catalyst via C-H/N-N bond activation via C-H/N-N functionalization of 1-(diphenylmethylene) hydrazine and aryl substituted acetylenes. In order to realize the proposed protocol, Cu(OAc)2 and AgSbF6 are used as oxidant and additive respectively in PEG-400 biodegradable solvent. This protocol has a simple extraction procedure, uses biodegradable solvent, affords high atom economy, employs a reusable catalytic system, provides wide substrate scope with high yield of product, for the synthesis of isoquinoline derivatives
Design and Synthesis of Novel 1,2,3-triazolyl-pyrimidinone Hybrids as Potential Anti-HIV-1 NNRT Inhibitors
No full textDesign, Synthesis and Docking Studies of Novel 1, 2, 3-Triazolyl Phenylthiazole Analogs as Potent Anti-HIV-1 NNRT Inhibitors
No full textRu(II)/PEG-400: A green synthesis of indolyl-oxindoles and indolyl-cyclohexane-dione hybrids as potential antimicrobial agents
Get PDFA green and sustainable methodology has been successfully employed for the synthesis of 3-Indolyl-3-hydroxy oxindoles and 3-indolyl-3-hydroxy-5,5-dimethylcyclohexane-1,3-dione derivatives using Ru(II)/PEG-400 as a homogeneous recyclable catalytic system from substituted isatin with indole and dimedone. Short reaction time, simple extraction procedure, substrate scope with high yield of the product, biodegradable solvent and recyclability of the catalyst without loss of its activity enhances the efficiency of the proposed protocol. The synthesized compounds are studied for their antimicrobial activity
A green synthesis of isoquinolines using Ru(II)/PEG-400 as homogeneous recyclable catalyst via C-H/N-N bond activation
Get PDFA novel and green synthesis of 1-phenyl isoquinoline derivatives has been developed by using Ru(II)/PEG-400 as homogeneous recyclable catalyst via C-H/N-N bond activation via C-H/N-N functionalization of 1-(diphenylmethylene) hydrazine and aryl substituted acetylenes. In order to realize the proposed protocol, Cu(OAc)2 and AgSbF6 are used as oxidant and additive respectively in PEG-400 biodegradable solvent. This protocol has a simple extraction procedure, uses biodegradable solvent, affords high atom economy, employs a reusable catalytic system, provides wide substrate scope with high yield of product, for the synthesis of isoquinoline derivatives
