121,999 research outputs found
Role of BSP/Bilirubin Binding Protein and Bilitranslocase in glutathione uptake in rat basolateral liver plasma membrane vesicles.
No full textGlutathione (GSH) efflux in the liver is mediated by carrier proteins sensitive to membrane potential (electrogenic), and it is inhibited by organic anions. The hepatic uptake of tetrabromosulfophthalein (BSP) is also a carrier-mediated function accomplished at least by two different transport mechanisms, bilitranslocase (BTL) and BSP/Bilirubin Binding Protein (BBBP). The two proteins operate in parallel, the former operating electro-genically, the latter being insensitive to membrane potential (electroneutral). To investigate the relationship between transport mechanisms for GSH and organic anions, the initial uptake rate of 35S-labelled BSP into basolateral rat liver plasma membranes was measured in the presence of external or intravesicular GSH. Electrogenic and electroneutral BSP uptake were neither cis-inhibited nor trans-stimulated by GSH. 3H glycine-GSH uptake in LPMV was not modified by pre-incubating LPMV with anti-BTL or anti-BBBP antibodies. These data indicate that GSH hepatic uptake is mediated neither by BBBP nor BTL
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
The semantics of social influence: Threats vs. persuasion
No full textThis study investigates how language is used to make sense of influence attempts. More specifically, the Perceived potency and evaluation of both influence agents and targets and the influence tactic used are examined for their effect on the actors' perceived power and influence success. The two influence tactics examined are threats and attempts to persuade. A pilot study (N = 145) and main experiment (N = 189) were conducted to create 84 simple sentences, the units of analysis for this investigation. Agents are perceived as more powerful than targets of influence. The tactic used to secure compliance (threaten versus attempt to persuade) does not affect the perceived power of either the agent or the target. A bad agent is seen as more powerful than a good agent, and a bad target is considered more powerful than a good target. Furthermore, good agents have more success in gaining compliance by using persuasion than by using threats, and they have more success when influencing a good target than a bad target. Implications of these findings are discussed.
TAUROURSODEOXYCHOLIC ACID PROTECTS HEPATOCYTES FROM ETHANOL-FED RATS AGAINST TUMOR NECROSIS FACTOR-INDUCED CELL DEATH BY REPLENISHING MITOCHONDRIAL GLUTATHIONE.
No full textMitochondrial function, dysfunction, and adaption in the liver during the development of diabetes.
No full textDissipative Range Scaling of Higher Order Structure Functions for Velocity and Passive Scalars
No full textDifferently to Kolmogorov's second similarity hypothesis, we find that the 2n-th order velocity and scalar structure functions scale with n-th order moment of the energy dissipation and the scalar dissipation, respectively. The origins of this scaling are analyzed by the transport equations of the fourth order velocity and scalar increment moments and by direct numerical simulations
Fast implementation of iterative adaptive approach for wideband unambiguous radar detection
No full textAccepted author manuscriptMicrowave Sensing, Signals & System
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