19 research outputs found

    A rare reaction to synthetic mono-filament sutures: a report of two cases

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    Due to their clinical advantages, synthetic mono-filament sutures are dominantly used for postoperative wound closures. We present two patients who suffered rare skin reactions to either poliglecaprone 25 or glyconate sutures, following breast cancer lumpectomy. This report aims to make perioperative practitioners and clinicians aware of reactions to sutures and possible management options.</jats:p

    Acute burn injuries associated with long-term mortality:a systematic review and meta-analysis

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    Background: Emerging evidence suggests that the pathophysiological impact of acute burn injuries may have chronic health consequences. We conducted a systematic review and meta-analysis to investigate the association between burn injuries and long-term mortality in patients surviving to initial discharge from hospital.Methods: Medline and Embase databases were searched on 22 October 2021. Studies were eligible for inclusion if they compared long-term mortality amongst burn survivors to non-injured controls from the general population. When the same output metrics related to mortality were reported, meta-analyses were undertaken using a random effects model. Risk of bias was assessed using the Joanna Briggs Institute (JBI) critical appraisal tool.Results: Following an extensive literature search, six studies (seven articles) were identified for inclusion. They were predominantly based in high-income countries, with each comparing burns' survivors to matched non-injured controls from the general population. The four studies included in the meta-analysis had a combined unadjusted odds ratio of 2.65 (1.84 - 3.81; 95 % confidence interval) and adjusted mortality rate ratio of 1.59 (1.31 - 1.93; 95 % confidence interval). Thus, burn survivors demonstrated greater mortality rates when compared to their non-injured counterparts. Similar findings were illustrated in the remaining studies not included in the meta-analysis, with the exception of one study which found no significant difference between the two groups.Conclusions: Our review suggests that acute burn injuries may be associated with greater long-term mortality rates (unadjusted and adjusted). The underlying mechanism is unclear and further work is required to establish the role of certain factors such as biological ageing processes, to improve outcomes for burn patients

    Beliefs about delusions

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    Early in his third month of office, President Reagan was on his way to address a conference when John Hinckley fired six gun shots at point blank range, wounding the president and three of his entourage. In the controversial trial that followed, three defence psychiatrists successfully argued that Hinckley was not guilty, on the grounds that he was suffering from the delusion that the assassination would cause Jodie Foster, the actress from Taxi Driver (a film which Hinckley was obsessed with), to fall in love with him. In the same year the award-winning author Philip K. Dick, whose books have been turned into major Hollywood films, such as Blade Runner, Total Recall and Minority Report, published one of his last books. The sprawling and eccentric VALIS is a novel based on delusions resulting from his own psychotic breakdown, which he drew on for much of his prolific career (see box). From these and many other examples, it would appear that unusual or unlikely beliefs have significant consequences and continue to captivate the interest of many of us. But to examine such claims we need to know what is meant by a delusion. How do delusions differ from other abnormal beliefs? Does the study of delusions provide a productive way of understanding beliefs
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