1,722,945 research outputs found
Performance Issues in the Operating System for the Page-based Distributed Shared Memory Machine
No full textElectrochemical determination of total alkaline phosphatase in human blood with a micropatterned ITO film
No full textA voltammetric determination of alkaline phosphatase (ALP), a well-known enzyme in human blood, was investigated to survey the feasibility for a health diagnosis sensor. Simple photolithography with an office printer and transparency film was employed to construct an electrochemical sensor with an Indium tin oxide (ITO) film on glass. ITO films can be easily patterned with a resolution of 50 mu m, and an integrated sensor consisting of working, counter and reference electrodes on a single ITO plate was constructed by this method. We used p-nitrophenyl phosphate (PNPP) as the substrate for ALP. PNPP was hydrolyzed enzymatically, and the product p-nitrophenol was detected by cyclic voltammetry and square wave voltammetry at an oxidation potential of +1.1 V (versus a fabricated Ag vertical bar AgCl reference electrode) on a bare ITO electrode. According to this method, ALP can be detected in various media including fetal bovine serum, human serum and untreated human blood. The linear dynamic range of ALP was 5-180 units per liter (U/L). This method showed a good enough performance for applications and was sufficiently reproducible. Results were further examined via comparison with medical standard colorimetric analysis. (c) 2004 Elsevier B.V. All rights reserved.This work was partially supported by the Brain
Korea 21 project and the Korea Science and Engineering
Foundation through the MICROS center at KAIST.
The authors thank the staff of the Health Care Center
for their kind cooperation in providing blood samples
Characterization of a 14 in x 17 in flat panel detector based on ion shower doped a-Si : H P-I-N diodes
No full textIn recent years, it has become technically and economically feasible to use solid-state detector technology to display, store and transfer X-ray images. In this paper, we report the performance of a 33 cm x 41 cut amorphous silicon flat panel detector (FPD) based on an ion shower doped P-I-N photodiode/thin-film transistor (TFT) array. The p-layer of a diode is formed by an ion shower doping method instead of the conventional plasma-enhanced chemical vapor deposition method. Measurements of X-ray imaging performances are reported for general imaging metrics such as modulation transfer function, noise power spectrum and detective quantum efficiency. The presampling MTF was found to be 0.51 and 0.26 at 1 lp/mm and 2 lp/mm. The measured DQE at I lp/mm and 2 lp/mm was 0.35 and 0.17.This work was supported
by the Korea Ministry of Commerce, Industry and Energy
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric observation of a peptide triplet induced by thermal cleavage of cystine
No full textHeat-induced (90 degreesC, 30 min) beta -elimination of a cystine residue leads to cleavage of a disulfide bond and produces a set of three peptides with a cysteine residue, a thiocysteine residue (+32Da), and a dehydroalanine residue (-34Da). This characteristic feature was observed from somatostatin and insulin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Mass spectrometric observation of this triplet is useful in identifying the presence of a cystine residue in a peptide, and could assist mass spectrometric identification of the peptide from a database. Copyright (C) 2001 John Wiley & Sons, Ltd.N
Adhesion and reliability of Anisotropic Conductive Films (ACFs) joints on Organic Solderability Preservatives (OSPs) metal surface finish
No full textRacial/Ethnic Disparities in Patient-Provider Communication and the Role of E-Health Use
No full textAlthough the health care industry has strived to address racial/ethnic disparities in health communication, several gaps remain. Previous findings suggest that communication technology might help narrow the gaps; however, they do not provide a comprehensive picture of how or why. To answer these questions, we examined the potential role of communication technology in mitigating the racial/ethnic disparities in patient-provider communication. Data analysis of the 2018 Health Information National Trends Survey (N= 3,504) revealed that the levels of perceived quality of communication with health care providers were lower among Asians and Hispanics than non-Hispanic Whites while no difference emerged between Blacks and non-Hispanic Whites. Although the adoption of communication technology was relatively high across minority groups, its use appeared to play different roles in different racial/ethnic populations. The Internet and patient portals showed no particular associations with patient-provider communication except for Black Internet users, who reported poorer experiences with patient-provider communication than non-users. Among Asians and Hispanics, social media and mobile communication appeared to play different roles in impacting communication experiences with health care providers. The findings suggest that communication technologies need to be strategically utilized and tailored to better meet the communication needs of racial/ethnic minorities
Suppression of matrix clusters and enhancement of peptide signals in MALDI-TOF mass spectrometry using nitrilotriacetic acid
No full textMatrix clusters and their alkali metal ion adducts suppress peptide signals in the 500-1400 Da range and compromise MALDI-TOF mass spectrometric peptide mass fingerprinting and protein identification. Addition of 7 mM nitrilotriacetic acid to the matrix solution significantly reduced matrix clusters and increased signal-to-noise ratio of peptide signals similar to 5 to 20-fold. As a result, reliability in the identification of femtomole amounts of proteins based on peptide mass fingerprinting and database search was significantly enhanced, leading to a higher score and sequence coverage.N
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