4,017 research outputs found
FT-infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines
No full textThis paper presents a novel method to characterise spectral differences that
distinguish leukaemia and lymphoma cell lines. This is based on objective
spectral measurements of major cellular biochemical constituents and
multivariate spectral processing. Fourier transform infrared (FT-IR) maps of the
lymphoma, lymphoid and myeloid leukaemia cell samples were obtained using a
Perkin-Elmer Spotlight 300 FT-IR imaging spectrometer. Multivariate statistical
techniques incorporating principal component analysis (PCA) and linear
discriminant analysis (LDA) were used to construct a mathematical model. This
model was validated for reproducibility. Multivariate statistical analysis of
FTIR spectra collected for each cell sample permit a combination of unsupervised
and supervised methods of distinguishing cell line types. This resulted in the
clustering of cell line populations, indicating distinct bio-molecular
differences. Major spectral differences were observed in the 4000 to 800 cm-
1 spectral region. Bands in the averaged spectra for the cell line were assigned
to the major biochemical constituents including; proteins, fatty acids,
carbohydrates and nucleic acids. The combination of FT-IR spectroscopy and
multivariate statistical analysis provides an important insight into the
fundamental spectral differences between the cell lines, which differ according
to the cellular biochemical composition. These spectral differences can serve as
potential biomarkers for the differentiation of leukaemia and lymphoma cells.
Consequently these differences could be used as the basis for developing a
spectral method for the detection and identification of haematological
malignancies
EXOTIC D-QUARK DECAY WITH GLUON EMISSION IN SUPERSTRING THEORIES
No full textThe decay process D → dg is investigated in the framework of SUL (2) x UY (1) x UY' (1) superstring theories. The width of this decay is calculated, and its dependence on the D-quark mass is investigated. A comparative analysis of different D-quark decay modes is carried ou
From Canon Road, 900 ft. above river, S.E. to Upper Falls (109 ft. high), Yellowstone Park, U.S.A.
No full textFrom Canon Road, 900 ft. above river, S.E. to Upper Falls (109 ft. high), Yellowstone Park, U.S.A
Electric Peak (11155 ft.), highest elevation in Yellowstone Park, U.S.A.
No full textElectric Peak (11155 ft.), highest elevation in Yellowstone Park, U.S.A
Old Faithful in action (150 ft.), the chief attraction of the Upper Geyser Basin, Yellowstone Park, U.S.A.
No full textOld Faithful in action (150 ft.), the chief attraction of the Upper Geyser Basin, Yellowstone Park, U.S.A
Most famous sight in Yellowstone Park - "Old Faithful" Geyser in action (height, 180 ft. 1,500,000 gallons each eruption), U.S.A., The
No full textMost famous sight in Yellowstone Park - "Old Faithful" Geyser in action (height, 180 ft. 1,500,000 gallons each eruption), U.S.A., Th
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