1,734 research outputs found
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Ullmann-type C–Se Cross-Coupling in the Hydantoin Family: Synthesis, Mechanistic Studies, and Tests of Biological Activity
No full textAn
attractive strategy for C–Se bond formation by Ullmann-type
copper(I)-promoted cross-coupling is developed. A wide range of aryliodides
reacts with various disubstituted 2-selenohydantoins under mild conditions
and provides Se-arylated imidazolines in moderate to high yields.
Computational mechanistic studies show the oxidative addition/intramolecular
reductive elimination likely to be the lowest-energy pathway. Cytotoxic
activity of all 43 reaction products has been tested in vitro against
MCF7 and A549 cancer cell lines with VA13 and MCF10a control cells
Sea Surges in Camargue: Trends over the 20th century.
No full textContinental Shelf Research 27 (2007) 922–934
Sea surges in Camargue: Trends over the 20th century
A. Ullmanna,b,, P.A. Pirazzolic, A. Tomasind,e
aUFR des Sciences Ge´ographiques et de l’Ame´nagement, Universite´ d’Aix-Marseille I, Aix en -Provence, France
bCEREGE—UMR 6635, Aix en Provence, France
cCNRS-Laboratoire de Ge´ogrphie Physique, 1 place Aristide Briand, 92 195-Meudon, France
dCNR-ISMAR, Venezia, Italy
eUniversita` di Venezia, Venezia, Italy
Received 8 November 2005; received in revised form 24 November 2006; accepted 4 December 2006
Available online 25 January 2007
Abstract
The vulnerability to short-term and long-term sea-level rises is particularly high in subsiding deltaic areas, especially in
microtidal seas, when surges (the differences between the observed sea heights and the simultaneous astronomical tide) are
frequent. At the Grau-de-la-Dent tide-gauge in the Camargue (Rhone delta, France), daily sea-level records are available
since 1905. Hourly tide data spanning the period 1979–1995 were obtained through the digitisation of the original paper
records: the local harmonic constants and the surges for the whole 20th century have been computed from these hourly
observations. It appears that the annual maximum observed sea-level height increases by 4 mm/yr at a rate that is two
times faster than the average observed relative sea level. The increasing trend of the annual maximum positive sea surges
(+1.9 mm/yr), which is equal to the average relative sea-level rise, is thus responsible for this difference. The most
important meteorological factor associated with local sea-surge occurrences is wind blowing from 1001 to 1201 sectors,
which tends to push the water toward the coasts. Since 1961, the frequency and the speed of wind from this sector
increased, although with some variability, thus contributing in part to the increase in the frequency and intensity of the
surges. Due to the changing hydrodynamics phenomenon in the Camargue, a positive feedback mechanism between
extreme marine events and shoreline regression is another factor to explain the sea-surge rise over the long term. The
increase in sea-surge frequency and height during the last century is especially of concern in the deltaic area if the nearfuture
global sea-level rise predicted by climate models is also taken into account.
r 2007 Elsevier Ltd. All rights reserved.
Keywords: Sea level; Surge; Tide; Wind; Flooding risk; Camargue; Rhone delta
1. Introduction
Any rise in sea level will have adverse impacts
such as coastal erosion and flooding, depending on
the time scale and the magnitude of the rise and the
human response to it (Paskoff, 1993). A rise in sea
level may be due to several factors acting on various
time scales, i.e., atmospheric storms (Bouligand and
Pirazzoli, 1999; Pirazzoli, 2000; Trigo and Davies,
2002; Pirazzoli and Tomasin, 2002), river flooding
in estuaries (Svensson and Jones, 2002), but also
land sinking or similar non climate-related changes,
linked to sediment compaction, isostasy, coastal
geomorphologic evolutions or urban development.
ARTICLE IN PRESS
www.elsevier.com/locate/csr
0278-4343/$ - see front matter r 2007 Elsevier Ltd. All rights reserved.
doi:10.1016/j.csr.2006.12.001
Corresponding author. CEREGE, Europoˆ le Me´diterrane´en
de l’Arbois, B.P 80, 13545 Aix-en-Provence, France.
E-mail address: [email protected] (A. Ullmann)
Synthesis of new tetrathianaphthalene derivatives by Ullmann-type reaction
No full textJaunu tetratianaftalēnu atvasinājumu sintēze Ulmaņa tipa reakcijās. Karpicka D., zinātniskais vadītājs Dr. chem. Šubins K., Maģistra darbs, 57 lappuses, 32 attēli, 3 tabulas, 61 literatūras avoti. Latviešu valodā. Maģistra darbs ir veltīts jaunu tetratianaftalēna kodola saturošu atvasinājumu sintēzei, kas ir saistīti ar tiofēna, acenaftilēna vai benzola gredzenu un var kalpot kā potenciāli metālorganisko ietvaru (MOI) ligandi. Apkopota informācija par Ulmaņa tipa vara katalizētām C-S sametināšanas un Sonogaširas reakcijām, reakcijas mehānismiem un visbiežāk izmantotiem reaģentiem.Synthesis of new tetrathianaphthalene derivatives by Ullmann-type reaction. Karpicka D., supervisor Dr. chem. Shubin K., Master’s thesis, 57 pages, 32 figures, 3 tables, 61 literature references. In Latvian. Master’s thesis is dedicated to the elaboration of new derivatives with tetrathianaphthalene core, fused with thiophene, acenaphthylene or benzene moieties as potential metal-organic framework (MOF) ligands. The Ullmann-type copper-catalyzed C-S coupling and Sonogashira reactions, their mechanism and scope is provided
Ortho-nitro-promoted Ullmann ether synthesis: application in the syntheses of K-13 and the isodityrosine unit of vancomycin
No full textA nitro group in the ortho-position of the aryl halide component facilitates Ullmann ether synthesis for the syntheses of all isodityrosine units present in wide variety of natural products, first time, on the basis of a common strategy
Optical probe study of a nonentangling macromolecule solution--bovine serum albumin: Water
No full textThe diffusion coefficient D of polystyrene latex spheres in bovine serum albumin:water was studied as a function of protein concentration c for 0 c D fails by as much as 25 to 50%, D being larger than predicted from the sphere radius R and the solution viscosity. Probe particles with R as large as 0.62 [mu]m were used. D fits well to the form D = Doexp(-[alpha]cv) for [alpha] = 0.004 to 0.008 and v = 0.96 to 0.99. Serum albumin is a globular protein, so chain entanglement cannot cause these non-Stokes--Einsteinian effects, which are presumably due to sphere:albumin interactions. Polystyrene spheres in semidilute polyethylene oxide:water (G. S. Ullmann, K. Ullmann, R. M. Lindner, and G. D. J. Phillies, J. Phys. Chem. 89, 692 (1985)) behave similarly to spheres in serum albumin:water, suggesting that chain entanglement may also not be important in probe diffusion through semidilute polymer solutions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25653/1/0000205.pd
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