599 research outputs found
Creighton University Window Spring 1991
No full textTHE PLATTE: A TREASURE AT RISK / THE FLAT PLATTE: AN IMPERILED TREASURE OF NEBRASKA, PLAINS
Dr. John Schalles, Creighton biologist, and Don Doll, S.J., photographer, take you on a tour of the Platte River system, a three-state treasure of which everyone wants a piece. Page 4.
SHAKESPEARE IN THE PARK / TRY A NIGHT OUT... ON THE LAWN ... WITH SHAKESPEARE
Brian Kokensparger and photographers Don Doll, S.J., Tim Fitzgerald of University of Nebraska at Omaha, and Kent Sievers show you how Shakespeare is done on a midsummer's night as you'll like it. Page 14.
SHE SWINGS FOR THE FENCES / COACH HIGGINS SWINGS FOR THE FENCES FOR CREIGHTON, FAMILY
Mary Higgins has brought the Lady Jay softball team to national prominence. For her, family or Creighton are the same — she goes for the home run all the time. Read about this enthusiastic top Lady Jay. Page 18.
THE BLACKROBE IN LITERATURE / THE JESUITS IN LITERATURE: SALVOS FROM WRITERS' PENS
Author Bob Reilly researches the references to Jesuits in literature that trace back to their beginnings. Sometimes it's not flattering, but it's always intriguing. Page 21.3
Humanizing Mathematics: An Amalgamation of Constructionist Theory and Situated Cognition in the Mathematics Classroom
Get PDFA primary contributor to facilitating student learning in mathematics includes the mathematics teacher. The design of instructional delivery, presentation of engaging activities and analysis of student feedback are the key responsibilities that mathematics teachers are tasked with in order to present learning opportunities to the students. The approach to satisfying these responsibilities is contingent on the teachers' values and beliefs regarding the various aspects of mathematical proficiency. In this study, I have investigated teachers' valuation of two of these aspects: procedural fluency and conceptual understanding. The literature on these two aspects of mathematical proficiency has focused almost exclusively on elementary teachers. Research studies have uncovered a proclivity of elementary teachers toward procedural learning despite the abstract nature of mathematical processes. Elementary teachers have been found to possess a certain aversion toward a deeper conceptual understanding of mathematics. With regard to secondary teachers, the research is more focused on instructional strategies that emphasize mathematical concepts, but neglect the relationship that these concepts may have to the robust procedures that allow students to process known values as they attempt to discover solutions to both prescribed and unique problems. This study examined the values that secondary teachers place upon two learning constructs within the framework of mathematical proficiency, and how these values influence their approach to teaching. "How do secondary mathematics teachers value procedural fluency and conceptual understanding in their instructional practices?" is the fundamental question of this study. The study reaches beyond this initial question to also examine the root causes of the establishment of these values by asking "how do teachers develop their value-system of procedural fluency and conceptual understanding in their instructional practices?". This study consisted of two phases. In phase one, teachers completed a 27-item survey instrument in order to gather responses about their beliefs regarding conceptual understanding, procedural fluency and a blend of the two constructs. Phase two consisted of a focus group interview of teachers to delve deeper into the source of the various belief systems that serve as the foundation for mathematics instruction in secondary schools in southeastern Pennsylvania.Ed.D., Educational Leadership and Management -- Drexel University, 201
Book Review: Practical Techniques for Habitat and Wildlife Management
No full textBook Title: Practical Techniques for Habitat and Wildlife ManagementBook Author: Ken Coetzee2016, New Voices Publishing, PO Box 95, Philadelphia 7304, Cape Town, South Africa329 pages, softcoverISBN 978-0-986708-44-9. Price R29
Macrophages and T regulatory cells: immune mediators of allogeneic and xenogeneic Sertoli cells
No full textThere is a critical shortage of organ donors available for clinical transplantation and
recipients rely on toxic life-long immunosuppression to prevent allograft rejection.
Xenotransplantation could alleviate this shortage however one substantial barrier is rapid tissue
rejection. Therefore, ways to improve both allo- and xeno-transplantation survival with decreased
immunosuppression are vastly needed. Immune privileged Sertoli cells (SCs) survive long term
post allo- and xeno-transplantation without immunosuppression and protect co-transplanted issue
from immune rejection. Based on these findings, we are working to uncover the underlying
mechanisms utilized by SCs to evade both allo- and xeno-geneic rejection. Our long term goal is
to exploit these mechanisms to improve clinical transplantation survival with little to no need for
immunosuppression and to advance the efficacy of xenotransplantation as a solution to the
recipient donor disparity. Previously, SC allo- or xeno-grafts collected between days 1-20 post
transplantation were analyzed for differences in the immune response. In both models, SCs
established an anti-inflammatory environment compared to the rejected controls. Macrophages
were the main infiltrating immune cells and T regs, known to induce graft tolerance, appeared
early and later in the xeno- and allo-grafts, respectively. In this study, we identified T regs in our
xenotransplantation model for the first time. Interestingly, we found that xenogeneic SCs inhibit
both alterative and classical pathways of complement mediated cell lysis prior to graft infiltration
of T regs. Furthermore, significantly more M2 or anti-inflammatory macrophages were present
early in the SC allografts and following macrophage depletion, 33% of the normally rejected
control allografts survived without immunosuppression. Conversely, SC survival was not affected
following macrophage depletion. Altogether, this suggests that SCs survive by establishing graft
tolerance early through adaptive (T regs) immune responses post allo- and xeno-transplantation.
Specifically, in the xenotransplantation model it suggests that complement inhibition plays a
significant role in mediating graft survival. Overall these data implicate T regs as important
immune cells mediating SC survival in both models and macrophages in control allograft rejection. The role of macrophages in SC grafts remains unclear and requires additional study. Future studies will identify M2 macrophages in SC xenografts and evaluate xenograft survival
following macrophage depletion. Allograft survival will also be evaluated following either M1 (proinflammatory)
or M2 specific macrophage depletion. Ultimately, these mechanisms will advance
our knowledge regarding ways to improve both allo- and xeno-graft survival with less need for
immunosuppression and bring xenotransplantation practices closer to fruition.Restricted until January 2025
Recommended from our members
Multiplexing Techniques Applied to Ion Mobility Measurements
Get PDFIon mobility spectrometry (IMS) is an analytical technique that provides rapid separation of gas-phase ions. IMS is capable of measuring the gas-phase mobility coefficient (K) of ions under specific operational conditions. IMS devices are increasingly coupled to the front-end of mass spectrometers (MS) which can simultaneously measure drift time and m/z to provide ion density measurements. The combined chemical information provided by IMS-MS instruments enables rapid separation of isomers and isobars which can be useful for the identification of unknown compounds. The greater peak capacity and ion manipulation afforded by modern high resolution mass spectrometers places a premium on maximizing ion transfer to the mass detector without sacrificing the separation and chemical information afforded by IMS.The common method of gating ions into the drift cell of IMS devices at atmospheric pressure suffers from low duty cycles that limits the ions ultimately transmitted to the mass detector. To increase ion transmission without physical modifications to the IMS device it is necessary to increase the duty cycle of the IMS gate achieved by increasing the gate pulse width or incorporating multiplexing strategies. The gate pulse width is a crucial parameter in IMS operation that influences the resulting sensitivity and resolution. Multiplexing techniques for IMS instruments traditionally incorporate either the Fourier or Hadamard transform which have not yielded the signal-to-noise ratio improvement predicted by theory at the higher gating duty cycles. The application of the proposed signal processing techniques are tailored to IMS-MS measurements and demonstrated to realize enhanced signal-to-noise ratio without sacrificing resolution or duty cycle of the ion gate. The signal processing technique known as cross-correlation IMS is demonstrated with IMS resolution that approaches the theoretical limit. This signal processing technique is applied for the purpose of identifying the surrounding chemical environment of the uranyl for attribution purposes. Additionally, the use of a signal processing technique known as basis pursuit denoising is demonstrated and applied for improved resolution at extended gating duty cycle with applications of mobility measurements acquired using slow acquisition mass detectors and combining individual IMS measurements across multiple electric fields for accurate mobility measurements
Actualistic studies of the spatial and temporal distribution of terrestrial and aquatic organism traces in continental environments to differentiate lacustrine from fluvial, eolian, and marine deposits in the geologic record
No full textActualistic studies of modern continental environments and the spatial and temporal distribution of terrestrial and aquatic organisms are summarized and synthesized to understand how to better interpret the significance of trace fossils to differentiate lacustrine from fluvial, eolian, and marine deposits in the geologic record. The purpose of this approach is to develop an understanding of the physicochemical factors that control the occurrence, diversity, abundance, and tiering of organism behavior and parallels what is known for benthic and other trace-making organisms in marine environments. The distribution of traces observed in Lake Tanganyika and Lake Eyre, an overfilled lake in a tropical rift basin setting and an underfilled lake in an arid midlatitude ephemeral playa setting, respectively, are described, synthesized, and compared with the Mermia, Coprinisphaera, Termitichnus, Skolithos, and Scoyenia ichnofacies models proposed for continental environments. The comparisons show that all the models are inappropriate for the fluvial-lacustrine settings of Lake Tanganyika and Lake Eyre because the models do not support the environmental uniqueness or distinctive collection of traces across these environments, nor do they provide sufficient interpretive power. The multiple ichnocoenoses for each subenvironment observed in the balanced-filled and underfilled lacustrine systems more accurately record the environmental uniqueness and distinctive collection of traces found in each environment. Ichnocoenoses are better suited for continental depositional systems and their environments because they reflect the nature of processes and distribution of life in continental settings, which are inherently heterogeneous spatially and temporally. Ichnocoenoses also provide sufficient interpretive power for trace-fossil associations formed under different physicochemical conditions for each type of environment. General trends in trace-fossil diversity, abundance, distribution, and tiering are predicted for alluvial (fluvial), lacustrine, and eolian environments so that new models based on the distribution of ichnocoenoses and their sedimentary and pedogenic characteristics from outcrop and core can be constructed.Stephen T. Hasiotis, Brian F. Platt, Mark Reilly, Kathryn Amos, Simon Lang, David Kennedy, Jonathan A. Todd, and Ellinor Miche
Diminished Smell in a Teenage Girl
No full textDisorders of smell are rare, particularly in pediatric patients. The most common cause of transient anosmia is nasal obstruction associated with upper respiratory infections. Moreover, nasal polyps, nasal and nasopharyngeal tumors, and enlarged adenoids can cause obstruction of the nasal air circulation and thereby diminish the sense of smell.
Anosmia can often be difficult to confirm, particularly if a pediatric patient has true anosmia. Many children with olfactory dysfunction may not recognize their deficits, or often pretend to smell to please their parents, or prevaricate to attract attention. Moreover, long, complex olfactory tests are impractical owing to the short attention span of some young children, and are further limited because odor concepts require experience with odors that some children have yet to come across
November 2015 Paris terrorist attacks and social media use : preliminary findings from authorities, critical infrastructure operators and journalists
No full textCrisis communication is a key component of an effective emergency response. Social media has evolved as a prominent crisis communication tool. This paper reports how social media was used by authorities, critical infrastructure operators and journalists during the terrorist attacks that hit Paris on 13th November 2015. A qualitative study was conducted between January and February 2017 employing semi-structured interviews with seven relevant stakeholders involved in this communication process. The preliminary critical thematic analysis revealed four main themes which are reported in the results section: (1) social media is used in crisis times; (2) authorities gained situational awareness via social media; (3) citizens used social media to help one another; and (4) communication procedures changed after these critical events. In conclusion, authorities, citizens and journalists all turned to social media during the attack, both for crisis communication and for increasing situational awareness
- …
