64 research outputs found
Targeted sequencing identifies novel variants involved in autosomal recessive hereditary hearing loss in Qatari families
No full textHereditary hearing loss is characterized by a very high genetic heterogeneity. In the Qatari population the role of GJB2, the worldwide HHL major player, seems to be quite limited compared to Caucasian populations. In this study we analysed 18 Qatari families affected by non-syndromic hearing loss using a targeted sequencing approach that allowed us to analyse 81 genes simultaneously. Thanks to this approach, 50% of these families (9 out of 18) resulted positive for the presence of likely causative alleles in 6 different genes: CDH23, MYO6, GJB6, OTOF, TMC1 and OTOA. In particular, 4 novel alleles were detected while the remaining ones were already described to be associated to HHL in other ethnic groups. Molecular modelling has been used to further investigate the role of novel alleles identified in CDH23 and TMC1 genes demonstrating their crucial role in Ca2+ binding and therefore possible functional role in proteins. Present study showed that an accurate molecular diagnosis based on next generation sequencing technologies might largely improve molecular diagnostics outcome leading to benefits for both genetic counseling and definition of recurrence risk
Spin-polarized hole transport through a diluted magnetic semiconductor heterostructure with magnetic-field modulations
No full textWe investigate the spin-polarized transport of holes in symmetric and
asymmetric diluted magnetic semiconductor heterostructures of
CdTe/CdMnxTe under local magnetic-field modulations. The effect
of a type-I–to–type-II transition in the CdTe/CdMnxTe heterostructure is also used in our model. The
spatially modulated magnetic field provides us with a new degree of freedom to
control the degree of spin-polarized transport of holes. Our investigations
show that spin-polarized transport of holes reaches 100% polarization
with modulated weak magnetic field. This could be suitably engineered in the
fabrication of perfect magnetic semiconductor spin-filters
Spin-polarized transport through a time-periodic non-magnetic semiconductor heterostructure
No full textSpin-dependent Floquet scattering theory is developed to investigate the photon-assisted spin-polarized electron transport through a semiconductor heterostructure in the presence of an external electric field. Spin-dependent Fano resonances and spin-polarized electron transport through a laser irradiated time-periodic non-magnetic heterostructure in the presence of Dresselhaus spin-orbit interaction and a gate-controlled Rashba spin-orbit interaction are investigated. The electric field due to laser along with the spin-orbit interactions help to get spin-dependent Fano resonances in the conductance, whereas the external bias can be appropriately adjusted to get a near 80% spin-polarized electron transmission through heterostructures. The resultant nature of the Floquet scattering depends on the relative strength of these two electric fields. Copyright EDP Sciences/Società Italiana di Fisica/Springer-Verlag 200685.75.Mm Spin polarized resonant tunnel junctions, 72.20.-i Conductivity phenomena in semiconductors and insulators, 73.40.Gk Tunneling, 73.63.Hs Quantum wells,
Pressure dependence of the diamagnetic susceptibility of a donor in low-dimensional semiconductor systems
No full textSuper Fibonacci Graceful Labeling
No full textAbstract: A Smarandache-Fibonacci Triple is a sequence S(n), n ≥ 0 such that S(n) = S(n−1)+S(n−2), where S(n) is the Smarandache function for integers n ≥ 0. Certainly, it is a generalization of Fibonacci sequence. A Fibonacci graceful labeling and a super Fibonacci graceful labeling on graphs were introduced by Kathiresan and Amutha in 2006. Generally, let G be a (p,q)-graph and {S(n)|n ≥ 0} a Smarandache-Fibonacci Triple. An bijection f: V (G) → {S(0), S(1), S(2),..., S(q)} is said to be a super Smarandache-Fibonacci graceful graph if the induced edge labeling f ∗ (uv) = |f(u) − f(v) | is a bijection onto the set {S(1), S(2),..., S(q)}. Particularly, if S(n), n ≥ 0 is just the Fibonacci sequence Fi, i ≥ 0, such a graph is called a super Fibonacci graceful graph. In this paper, we construct new types of graphs namely Fn ⊕ K + 1,m, Cn ⊕ Pm, K1,n ⊘ K1,2, Fn ⊕ Pm and Cn ⊕ K1,m and we prove that these graphs are super Fibonacci graceful graphs
Carrier mobility in a quantum well wire-distribution dependence
No full text752-756The carrier mobility in a quantum well wire
has been estimated in three different models. It is shown that the estimated mobility
values depend strongly on the type of impurity distribution employed
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