21 research outputs found
From managing equality to managing diversity:a critical Scandinavian perspective on gender and workplace diversity
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Men, Masculinities and Workplace Diversity/Diversion:Power, Intersections and Contradictions
No full textSkill enhancement for post graduate medical students
No full textThe medical students ought to be well versed with life saving measures like basic and advanced techniques and should also practice medicine in the most ethical manner in today’s healthcare environment. To provide a uniform formal training to all the post graduate medical students it was decided to start the BLS/ALS/GLP/GCP courses across the state using uniform modules developed by experts. To implement this uniformly, The Tamil Nadu Dr. M. G. R. medical university initiated training programs in advanced life support (ALS), basic life support (BLS), and good clinical practice (GCP), good laboratory practice (GLP) through eight designated nodal centres across Tamil Nadu. A total of 4,000 postgraduate medical students received training from qualified personnel. Pre and post training assessments were conducted to evaluate the effectiveness of the program. The feedback collected from students was highly encouraging, indicating a positive reception of the training modules, and reaffirming the program's value and effectiveness
Parabens: The love - hate molecule
No full textParabens are the esters of para-hydroxybenzoic acid [1], mimicking oestrogen, the hormone which makes a woman a woman; women love it and men hate it. 
Faecal Transplant Therapy: A Promising Treatment Modality for Cardiovascular Diseases
No full textCardiovascular diseases (CVD) are considered as “lifestyle” diseases and so far “No unified procedure” or medicines are effective in the management of this group of diseases. Researchers and clinicians have indicated that no safe therapeutic window is available in therapeutics at present. Recent research showed that gut microbiota are effective in managing lifestyle diseases therefore we introduced the influence of gut microbiota in the prognosis of the CVDs. Faecal transplant therapy(FMT) has been anticipated to treat many diseases similar to recurrent bacterial Clostridioides difficile infection which has been used worldwide. Recently, FMT was tried on an animal model to treat CVDs, and recent human trials that were tried to manage CVDs in humans by FMT showed encouraging results. The mechanism of action of transplanted bacteria to manage CVDs in the human population is also discussed. In-depth knowledge on the pros and cons of FMT will pave the way to standardize the procedure once the lacuna existing at present in treating CVDs, is paved, this technology will be useful for the masses
In-Silico Screening of Phytocompounds of Justicia Adhatoda for Thrombolytic Activity
No full textBackground: The risk of thrombosis and its associated mortality is becoming a greater public health concern in both industrialized and developing nations. Clinical condition that is myocardial infarction, ischemic stroke, unstable angina, peripheral vascular diseases like deep vein thrombosis prioritise top in the list of thrombotic disorders. Conventional thrombolytic medications including alteplase, anistreplase, streptokinase and urokinase offer life risking adverse effects like haemorrhage, stroke, vascular dysfunction, hypertension, internal bleeding and so on. In order to overcome the undesirable side effects caused by the conventional thrombolytic therapy, there is ominous need of alternate complementary treatment from traditional medicine. Majority of the Siddha formulations comprise of some potential medicinal herbs which are found to be biocompatible and also have a wide safety window. Justicia adhatoda is one such novel herb which is investigated broadly by researchers till date, aspired by its unique pharmacological property rendered by the bioactive components present in it. Methods: Hence, the present research is aimed at in-silico screening of certain classes of alkaloids and flavonoids retrieved from J. adhatoda to explore the possible anti-thrombotic activity against the target human plasminogen activation loop peptide using AutoDock screening tool. Results and Conclusion: The computational analysis’s findings led to the conclusion that the bioactive compounds present in Justicia adhatoda like Astragalin, Kaempferol, Vitexin, Vasicolinone and Adhatodine reveals significant binding affinity against target plasminogen. Thereby it was determined that these compounds may have promising anti-thrombotic efficacy due to their considerable binding affinity towards the target plasminogen
