346 research outputs found
Vibrational Circular Dichroism Unveils Chiroptical, Electrical, and Magnetic Properties of Borylated Isocyanides and Aldehydes
No full textErratum to: Sub-gap defect density characterization of molybdenum oxide: An annealing study for solar cell applications (Nano Research, (2020), 13, 12, (3416-3424), 10.1007/s12274-020-3029-9)
No full textRef. [56] was unfortunately wrong, Instead of [56] Corless, R. M.; Gonnet, G. H.; Hare, D. E. G.; Jeffrey, D. J.; Knuth, D. E. On the Lambert W function. Adv. Comput. Math. 1996, 5, 329–359. It should be changed to Biswas, R. K.; Khan, P.; Mukherjee, S.; Mukhopadhyay, A. K.; Ghosh, J.; Muraleedharan, K. Study of short range structure of amorphous Silica from PDF using Ag radiation in laboratory XRD system, RAMAN and NEXAFS. J. Non. Cryst. Solids 2018, 488, 1–9. Some entries in Table 2 were unfortunately misprinted.Photovoltaic Materials and DevicesElectrical Sustainable Energ
Immolation and critical document
No full textImmolation is a creative text comprised of 58 numbered fragments of dialogue between an unnamed author and editor. Their conversations take place over an extended period as the pair describe and discuss their middle-agedness, whilst the author attempts to create pieces of fiction which the editor critically assesses, and the editor talks about their faltering marriage. The text culminates in an extended story written by the author about a dysfunctional family, which the editor then provides commentary on. The fragments are less structured than a traditional novel and are presented as an intertwined and unconstrained creative experiment. The conversational estrangement and undefined medium of discourse between the author and editor provides a statement on modern relationships and forms of dialogue in contemporary life.
The critical document is comprised of two sections. The first is a series of fragmentary essays concerning my critical research as it relates to Geoff Dyer’s Out of Sheer Rage, a book which describes Dyer’s attempts to write about D. H. Lawrence. As with the creative piece, the section deals with themes of interactivity between pieces of work, experimentations in form, and authorial and editorial insertions as they relate to a finished critical piece. The argument, which is intertwined with and responds to Dyer’s analysis, is that the process of writing can itself become a “means of continuing”, and that there is hope and meaning in the dark patches of the process. The second section is a personal manifesto comprised of motivational writing-related quotations from a variety of sources, taking its major inspiration from Reality Hunger: A Manifesto by David Shields. The text draws on the themes of developing a healthy writing practice
Exploring Novel Chemical Space: From Small Molecules to Cyclic Peptides
No full textLipinski and Hopkins famously stated that “chemical space is for all practical purposes infinite and limited only by the chemist's imagination”. Chemists venturing forth to explore uncharted areas of chemical space are faced with the ongoing challenge of developing efficient synthetic strategies to access new and biologically relevant molecular architectures. This thesis reports on the development of novel chemoselective reactions and molecular building blocks to establish methods of synthesis for a variety of challenging scaffolds, from small molecules to medium-sized rings. In this area, organoboron reagents play indispensable roles in chemical synthesis, providing a versatile synthetic handle that is pivotal in accessing a broader chemical space. Boron-containing amphoteric molecules therefore represent a means for developing flexible, chemoselective routes to densely functionalized borylated molecules. Chapter 1 discusses the development of a new class of amphoteric building block, the dicarbonyl MIDA boronates, and their application toward previously inaccessible borylated heterocycles through condensation chemistry. Chapter 2 outlines a novel methodology for the synthesis of 8-11 membered medium-sized rings and cyclic tripeptides. This work is based on an integrative approach wherein cyclic amides are converted into more electrophilic imides, which subsequently undergo ring expansions to yield the desired rings. Finally, Chapter 3 describes an ongoing collaboration with the Structural Genomics Consortium in Toronto for the development of potent chemical probes for epigenetic protein targets. Target validation studies, which include optimizing expression, purification and crystallization of several proteins, as well as the development and screening of a small library of small molecules produced by members of the Yudin group are discussed in detail.Ph.D
Exploring Novel Chemical Space: From Small Molecules to Cyclic Peptides
No full textLipinski and Hopkins famously stated that “chemical space is for all practical purposes infinite and limited only by the chemist's imagination”. Chemists venturing forth to explore uncharted areas of chemical space are faced with the ongoing challenge of developing efficient synthetic strategies to access new and biologically relevant molecular architectures. This thesis reports on the development of novel chemoselective reactions and molecular building blocks to establish methods of synthesis for a variety of challenging scaffolds, from small molecules to medium-sized rings. In this area, organoboron reagents play indispensable roles in chemical synthesis, providing a versatile synthetic handle that is pivotal in accessing a broader chemical space. Boron-containing amphoteric molecules therefore represent a means for developing flexible, chemoselective routes to densely functionalized borylated molecules. Chapter 1 discusses the development of a new class of amphoteric building block, the dicarbonyl MIDA boronates, and their application toward previously inaccessible borylated heterocycles through condensation chemistry. Chapter 2 outlines a novel methodology for the synthesis of 8-11 membered medium-sized rings and cyclic tripeptides. This work is based on an integrative approach wherein cyclic amides are converted into more electrophilic imides, which subsequently undergo ring expansions to yield the desired rings. Finally, Chapter 3 describes an ongoing collaboration with the Structural Genomics Consortium in Toronto for the development of potent chemical probes for epigenetic protein targets. Target validation studies, which include optimizing expression, purification and crystallization of several proteins, as well as the development and screening of a small library of small molecules produced by members of the Yudin group are discussed in detail.Ph.D
Irish Demonstration, 4/1/20
No full textDate from caption list.Caption from caption list: WOMEN MARCH FOR FREE ERIN. Carrying banners urging the abrogation of all treaties with England until the Irish Republic is recognized, a delegation of women from New York, Boston, Chicago, Baltimore, and Washington past the White House and to the capitol today. They were led by Mrs. Thomas K. (Gertrude) Corless wife of the noted actor.Title from unverified data provided by the National Photo Company on the negatives or negative sleeves.Gift; Herbert A. French; 1947
Irish Demonstration, 4/1/20
No full textTitle from unverified data provided by the National Photo Company on the negatives or negative sleeves.Date from caption list.Caption from caption list: WOMEN MARCH FOR FREE ERIN. Carrying banners urging the abrogation of all treaties with England until the Irish Republic is recognized, a delegation of women from New York, Boston, Chicago, Baltimore, and Washington past the White House and to the capitol today. They were led by Mrs. Thomas K. (Gertrude) Corless wife of the noted actor.Gift; Herbert A. French; 1947
Computing greatest common divisors and squarefree decompositions through matrix methods: The parametric and approximate cases
No full textAbstractBarnett’s method through Bezoutians is a purely linear algebra method allowing to compute the degree of the greatest common divisor of several univariate polynomials in a very compact way. Two different uses of this method in computer algebra are introduced here. Firstly, we describe an algorithm for parameterizing the greatest common divisor of several polynomials in K[x,y], being x a parameter taking values in an real field K. Secondly, we consider the problem of computing the approximate greatest common divisor with limited accuracy for several univariate polynomials following Corless et al. [R.M. Corless, P.M. Gianni, B.M. Trager, S. Watt, The singular value decomposition for polynomial systems, in: ACM International Symposium on Symbolic and Algebraic Computation, 1995, pp. 195–207]. Given a family of polynomials whose coefficients are imperfectly known, we describe an algorithm for computing their approximate greatest common divisor by using, as main tools, Barnett’s method and singular value decomposition computations. Furthermore, we show how to use this algorithm in order to obtain the approximate squarefree decomposition of a given polynomial with imperfectly known coefficients
Garanteed Exponential Convergence for Uncertain Nonlinear Systems in the Presence of Singular Perturbations
No full textIrish Demonstration, 4/1/20
No full textTitle from unverified data provided by the National Photo Company on the negatives or negative sleeves.Date from caption list.Caption from caption list: WOMEN MARCH FOR FREE IRELAND. Carrying banners urging the abrogation of all treaties with England until the Irish Republic is recognized, a delegation of women from New York, Boston, Baltimore, Chicago, and Washington marched past the White House and to the Capitol today. They were led by Mrs. Thomas K. (Gertrude) Corless wife of the noted actor and the Capitol police force was kept busy to keep them from entering the capitol with their banners.Gift; Herbert A. French; 1947
- …
