3,707 research outputs found

    Miss Julie

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    The revelry of servants celebrating Midsummer's Eve contrasts with a neurotic noblewoman's anguish and self-denial following her all-too-brief romantic interlude with her coachman, who seduced her.Cast: Janet McTeer, Patrick Malahide.A performance of Fröken Julie / by August Strindberg ; translated by Michael Meyer

    Harriette Simpson Arnow, 1908-1986

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    A documentary film on southern Appalachian author Harriette Simpson Arnow. Directed by Herb E. Smith for Appalshop Productions in 1987

    A review of the reporting and handling of missing data in cohort studies with repeated assessment of exposure measures

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    Background: Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision. The STROBE guidelines von Elm et al. (Lancet, 370:1453-1457, 2007); Vandenbroucke et al. (PLoS Med, 4:e297, 2007) and the guidelines proposed by Sterne et al. (BMJ, 338:b2393, 2009) recommend that cohort studies report on the amount of missing data, the reasons for non-participation and non-response, and the method used to handle missing data in the analyses. We have conducted a review of publications from cohort studies in order to document the reporting of missing data for exposure measures and to describe the statistical methods used to account for the missing data. Methods: A systematic search of English language papers published from January 2000 to December 2009 was carried out in PubMed. Prospective cohort studies with a sample size greater than 1,000 that analysed data using repeated measures of exposure were included. Results: Among the 82 papers meeting the inclusion criteria, only 35 (43%) reported the amount of missing data according to the suggested guidelines. Sixty-eight papers (83%) described how they dealt with missing data in the analysis. Most of the papers excluded participants with missing data and performed a complete-case analysis (n = 54, 66%). Other papers used more sophisticated methods including multiple imputation (n = 5) or fully Bayesian modeling (n = 1). Methods known to produce biased results were also used, for example, Last Observation Carried Forward (n = 7), the missing indicator method (n = 1), and mean value substitution (n = 3). For the remaining 14 papers, the method used to handle missing data in the analysis was not stated. Conclusions: This review highlights the inconsistent reporting of missing data in cohort studies and the continuing use of inappropriate methods to handle missing data in the analysis. Epidemiological journals should invoke the STROBE guidelines as a framework for authors so that the amount of missing data and how this was accounted for in the analysis is transparent in the reporting of cohort studies. © 2012 Karahalios et al.; licensee BioMed Central Ltd

    The impact of missing data on analyses of a time-dependent exposure in a longitudinal cohort: A simulation study

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    Background: Missing data often cause problems in longitudinal cohort studies with repeated follow-up waves. Research in this area has focussed on analyses with missing data in repeated measures of the outcome, from which participants with missing exposure data are typically excluded. We performed a simulation study to compare complete-case analysis with Multiple imputation (MI) for dealing with missing data in an analysis of the association of waist circumference, measured at two waves, and the risk of colorectal cancer (a completely observed outcome). Methods. We generated 1,000 datasets of 41,476 individuals with values of waist circumference at waves 1 and 2 and times to the events of colorectal cancer and death to resemble the distributions of the data from the Melbourne Collaborative Cohort Study. Three proportions of missing data (15, 30 and 50%) were imposed on waist circumference at wave 2 using three missing data mechanisms: Missing Completely at Random (MCAR), and a realistic and a more extreme covariate-dependent Missing at Random (MAR) scenarios. We assessed the impact of missing data on two epidemiological analyses: 1) the association between change in waist circumference between waves 1 and 2 and the risk of colorectal cancer, adjusted for waist circumference at wave 1; and 2) the association between waist circumference at wave 2 and the risk of colorectal cancer, not adjusted for waist circumference at wave 1. Results: We observed very little bias for complete-case analysis or MI under all missing data scenarios, and the resulting coverage of interval estimates was near the nominal 95% level. MI showed gains in precision when waist circumference was included as a strong auxiliary variable in the imputation model. Conclusions: This simulation study, based on data from a longitudinal cohort study, demonstrates that there is little gain in performing MI compared to a complete-case analysis in the presence of up to 50% missing data for the exposure of interest when the data are MCAR, or missing dependent on covariates. MI will result in some gain in precision if a strong auxiliary variable that is not in the analysis model is included in the imputation model. © 2013 Karahalios et al.; licensee BioMed Central Ltd

    Pendekatan Pelayanan Kontekstual Melalui Musik Rohani Daerah Sub Suku Dayak Iban

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    The author discusses the contextual ministry approach through spiritual music in the language of the Iban Dayak tribe. In the Dayak Iban tribe, culture is still very fanatical, but that culture hasalso changed from generation to generation according to the times. Modern songs, local people find it difficult to understand the meaning of the song. That way, the authors are interested in using this opportunity to make an approach through the contextual service of the music of the Iban Dayak sub-tribe. The aim of the author is to approach the spiritual music of the Iban Dayak tribe. In this case, the research conducted by the author is using a descriptive approach with qualitative methods. By describing, explaining, describing what happened or studying what was the essence of the discussion. the author approaches by looking at the local culture. One of the approaches used by the writer to take this approach is to create spiritual songs in accordance with the language in the local area, so that the meaning of the songs created can be easily understood by the community. An example of the song is "Oh Bala Kaban", a traditional song from Dayak Ketungau Tengah.The author discusses the contextual ministry approach through spiritual music in the language of the Iban Dayak tribe. In the Dayak Iban tribe, culture is still very fanatical, but that culture hasalso changed from generation to generation according to the times. Modern songs, local people find it difficult to understand the meaning of the song. That way, the authors are interested in using this opportunity to make an approach through the contextual service of the music of the Iban Dayak sub-tribe. The aim of the author is to approach the spiritual music of the Iban Dayak tribe. In this case, the research conducted by the author is using a descriptive approach with qualitative methods. By describing, explaining, describing what happened or studying what was the essence of the discussion. the author approaches by looking at the local culture. One of the approaches used by the writer to take this approach is to create spiritual songs in accordance with the language in the local area, so that the meaning of the songs created can be easily understood by the community. An example of the song is "Oh Bala Kaban", a traditional song from Dayak Ketungau Tengah

    Research Integrity

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    The integrity of scientific research is fundamental to the advancement of knowledge and to public confidence and trust in science. Trust is at the core of research, and as the research enterprise becomes more complex and the challenges of the changing research environment grow, trust becomes paramount. Integrity of research is based on science’s core values; from these values stem expectations and norms that define rigorous and responsible research. This presentation will provide an overview of research integrity, highlight a few selected issues/topics, review the components of UNH’s Responsible Conduct of Research and Scholarship Program, and identify available resources. Presenter Bio Julie Simpson, Ph.D., is the Director of Research Integrity Services (RIS) at the University of New Hampshire (UNH) and an Affiliate Assistant Professor of College Teaching and of Education. She has worked at UNH for 27 years. Her office administers UNH’s human subjects protections, humane care and use of animals, and responsible conduct of research and scholarly activity (RCR) programs, as well as UNH’s financial conflict of interest in research (FCOIR) and HIPAA programs. She is a member of UNH’s IRB, IACUC, RCR Committee and UNH’s Radiation Safety Committee. She is UNH’s Research Integrity Officer (RIO), has participated in research misconduct investigations at UNH and at a sister institution. She co-developed and co-teaches UNH’s GRAD 930: Ethics in Research and Scholarship, a cross-disciplinary graduate seminar that has been offered since 2005. She was the UNH project director for an Office of Research Integrity (ORI) grant to develop web-based RCR training materials, and administered UNH’s ORI/Council of Graduate School’s RCR grant. She has presented on research integrity issues nationally and regularly presents in UNH classes on a variety of research integrity topics

    Peranan Guru dalam Menerapkan Metode Belajar Sebaya

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    The role of teachers to achieve KKM in the affective, spikomotor, and cognitive domains. In the reality of education, many students are unable to complete the KKM. Because, teachers are not able to find and apply appropriate, consistent, and continuous methods in the learning process applied by the teacher. Where, the teacher focuses more on students who easily understand the subject matter. So that students who have difficulty understanding lessons are ignored and end up skipping school or going to class. The author describes the peer learning method as an approach in improving the abilities of each student in the affective, spikomotor, and cognitive domains during daily, semester, and national exams in achieving KKM. The author uses qualitative methods in gathering information through observation and the accumulated results of affective, psychomotor, and cognitive values. The author hopes that this paper can be a contribution for schools in Jayawijaya, Wamena.Â

    JTT914445 Supplemental Material - Supplemental material for Video-interpreting for cognitive assessments: An intervention study and micro-costing analysis

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    Supplemental material, JTT914445 Supplemental Material for Video-interpreting for cognitive assessments: An intervention study and micro-costing analysis by Kerry Hwang, Anurika De Silva, Julie A Simpson, Dina LoGiudice, Lidia Engel, Andrew S Gilbert, Samantha Croy and Betty Haralambous in Journal of Telemedicine and Telecare</p
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