2,691 research outputs found

    ddRADseq reveals determinants for temperature-dependent sex reversal in Nile tilapia on LG23

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    Abstract Background In Nile tilapia sex determination is governed by a male heterogametic system XX/XY either on LG1 or LG23. The latter carries a Y-specific duplicate of the amh gene, which is a testis-determining factor. Allelic variants in the amh gene demonstrated to be major triggers for autosomal and temperature-dependent sex reversal. Further, QTL on LG23 and LG20 show a temperature-responsiveness with influence on the phenotypic sex relative to the sex chromosomes. Here we present a ddRADseq based approach to identify genomic regions that show unusual large differentiation in terms of fixation index (FST) between temperature-treated pseudomales and non-masculinized females using a comparative genome-scan. Genome-wide associations were identified for the temperature-dependent sex using a genetically all-female population devoid of amh-ΔY. Results Twenty-two thousand three hundred ninety-two SNPs were interrogated for the comparison of temperature-treated pseudomales and females, which revealed the largest differentiation on LG23. Outlier FST-values (0.35–0.44) were determined for six SNPs in the genomic interval (9,190,077–11,065,693) harbouring the amh gene (9,602,693–9,605,808), exceeding the genome-wide low FST of 0.013. Association analysis with a set of 9104 selected SNPs confirmed that the same genomic region on LG23 exerts a significant effect on the temperature-dependent sex. Conclusions This study highlights the role of LG23 in sex determination, harbouring major determinants for temperature-dependent sex reversal in Nile tilapia. Furthermore FST outlier detection proves a powerful tool for detection of sex-determining regions in fish genomes

    Agent (Capt.) Beck to Commissioner

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    UteLetter regards a purported \u27antogonism\u27 from White River Utes to the author, Agent Beck. Marisco

    The Legacy of Ulrich Beck in Asia: Introduction

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    This introduction briefly describes the relational trajectory between Ulrich Beck and Asia in the last few years. It draws particular attention to his last words about the role of Asia in the global risk community. Beck began to speak of the concept of metamorphosis in the 2014 Seoul conference as the correct key to understanding emancipatory catastrophism that he had expressed in the 2013 Potsdam conference. He was fascinated by the explanatory power of this concept and was driven to complete a book to explain the cosmopolitan change of the world from this perspective. With his advocacy of cities as cosmopolitan transformers, he urged Asian cities, particularly Seoul, to initiate United Cities of Asia' for a cosmopolitan cooperation for risk governance. Beck also suggested a parliament of risk actors' as a practical task to be realized in the future. In this introduction the author attempts to trace back the formation of these ideas by focusing on the interaction between Beck and Asia before his sudden passing.A&[email protected]

    Autoworker and acclaimed author Ben Hamper speaks at the Michigan Writers Series

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    In an appearance at the Michigan State University Main Library, autoworker and acclaimed author Ben Hamper talks about his career at the General Motors Truck and Bus Plant in Flint, Michigan and reads from various works, including his forward to the book "Working words: punching the clock and kicking out the jams" by M. L. Liebler and from his most famous work, "Rivethead", a cynical and humorous view of life in an auto plant. A question and answer session follows. Hamper is introduced by Michigan State University Professor John P. Beck for the Michigan State University Libraries' Michigan Writers Series

    Henri Temianka Correspondence; (jadwiga beck)

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    This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1133/thumbnail.jp

    The relationship between depression and self-mutilation in adolescence

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    Plan BThe importance of the relationship between depression and self-mutilation in the adolescent population is becoming more apparent. Analysis of these two variables demonstrates that they are correlated with one another in the adolescent population. The present study examines the relationship between depression and self-mutilation. Two scales, the Beck Depression Inventory II (Beck, 1996) and the Self-Harm Survey (Conterio, Lader, & Bloom, 1998) were administered to participants and the scores were correlated to determine whether a relationship existed between the two variables. Participants were residents from a residential treatment center for adolescents. Data analysis using Pearson’s r correlation coefficients were used to determine if there was a positive correlation between depression and self-mutilation. The t-test for independent means was utilized to determine if there was a difference between gender and self-mutilation, age and self-mutilation, as well as length of stay in the residential treatment facility and self-mutilation. The means and standard deviations were also determined for these variables. Statistical differences were indicated based on these findings. Implications of this study as well as recommendations for future studies on depression and self-mutilation were discussed in detail

    Exploring the Theory of Metamorphosis: In Dialogue with Ulrich Beck

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    © The Author(s) 2018. This interview with Ulrich Beck was undertaken in late August 2014. At this juncture Beck was preparing what was to be his final book, The Metamorphosis of the World (2016). The conversation is reflective of Beck's thinking around the theory of metamorphosis at that time and represents his views on the underlying dynamics of social transformation and the mobilizing power of global risks

    On the Origins of the Robert Beck Memorial Cinema

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    In this article, the Author explains the origins of The Robert Beck Memorial Cinema (RBMC), a microcinema located in New York City. The idea was to show movies that no one else could or would
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