459 research outputs found
Roles and opportunities for machine learning in organic molecular crystal structure prediction and its applications
No full textThe field of crystal structure prediction (CSP) has changed dramatically over the past decade and methods now exist that will strongly influence the way that new materials are discovered, in areas such as pharmaceutical materials and the discovery of new, functional molecular materials with targeted properties. Machine learning (ML) methods, which are being applied in many areas of chemistry, are starting to be explored for CSP. This overview will discuss the areas where ML is expected to have the greatest impact on CSP and its applications: improving the evaluation of energies; analyzing the landscapes of predicted structures and for the identification of promising molecules for a target property
Fiddler on the Roof (2008) | Costume Sketch 011
No full textPerformed: 21-24, 28 February - 2 March 2008; Set around 1905, Fiddler on the Roof is a musical with music by Jerry Bock, lyrics by Sheldon Harnick, and book by Joseph Stein. Tevye, a milkman in the village, attempts to maintain his Jewish traditions as outside forces encroach on his family. The director/music director was Eric Traynor, vocal director was Teresa Stricklin, choreographer was Dewayne Barrett, conductor was Jeremy Stovall, scenic designer and producer was Carlton Ward, costume designer was Freddy Clements, lighting design was David Keefer, technical director was Daryl Pauley, stage manager was Jacob Phillips, assistant stage manager was Rachel Bagley, assistant lighting designer and board operator was Alex Becker, sound engineer was Adam Ellis, scenic artists was Joshua Whitt, Amanda O\u27Hern, assistant costume designer was Kimberly Stark, wardrobe mistress was Nicole Hicks, wardrobe Gatlin Alldredge, costume shop supervisor was Randal Blades, and box office and promotions poster/program Jan Rhodes. Shown are costume sketches for Katie D. and Cindy M. This item is contained within the Clements drama production materials.https://digitalcommons.jsu.edu/clements_costumes/1346/thumbnail.jp
Spontaneous alpha oscillations and low-frequency activities are related to complementary aspects of cognitive control
No full textDSpace SAF Submission Ingestion Package generated from Vireo submission #14801 on 2020-02-28 at 17:24:28Made available in DSpace on 2020-03-02T22:18:20Z (GMT). No. of bitstreams: 2
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Previous issue date: 2019-12-12Embargo set by: Seth Robbins for item 113943
Lift date: 2022-03-02T22:18:25Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemTwo classes of activity dominate the resting-state human EEG power spectrum: alpha oscillations (which tend to be sustained), and low-frequency activities (which manifest themselves as short bursts of theta or non-oscillatory 1/f slope). Alpha power at rest has been shown to decrease with age and to correlate with intelligence. Here we propose that alpha facilitates proactive control, which requires the maintenance of processing sets in preparation for expected task conditions. In contrast, bursts of theta activity have been related to reactive control, which requires the update of task sets in response to unpredicted task demands. Less is known about 1/f slope in relation to cognitive control. To investigate these relationships, we recorded resting eyes-open and eyes-closed EEG from younger and older adults and subsequently tested their performance on a cued flanker task, expected to elicit both proactive and reactive control processes. Alpha power and 1/f slope were smaller in older adults, whereas theta power did not show age effects. Resting alpha power was predictive of cue utilization to prepare for the upcoming response stimulus, suggesting its relevance to proactive control. In contrast, both larger theta and 1/f slope were related to a larger congruency effect (slower responses to stimuli flanked by distractors). This suggests that resting theta and 1/f indicate greater trait-like sensitivity to distraction, reflected in frequent spontaneous updating operations. All predictive associations were present over and above the effect of age, suggesting that these EEG correlates could be used as measures of individual differences in cognitive control behavior.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-12-01The student, Grace Clements, accepted the attached license on 2019-12-11 at 16:09.The student, Grace Clements, submitted this Thesis for approval on 2019-12-11 at 16:19.This Thesis was approved for publication on 2019-12-12 at 09:53.U of I Only Restriction Lifted for Item 113943 on 2022-03-03T10:15:16Z
Larval lamprey distribution and habitat use in small stream channels on the Oregon coast
No full textPotential fish passage barriers have been identified in over 4,100 small streams (i.e., <8 m wide) in coastal Oregon basins from the Nehalem River south to the Coos River and may be blocking Pacific lamprey access to spawning and rearing habitat. The impact of these barriers is unknown because of a lack of information on how Pacific lampreys use these small stream habitats. We conducted a pilot study using multi-state occupancy modeling to better understand distribution, habitat use, and sampling detection of larval Pacific lampreys in small streams to improve monitoring techniques and begin to evaluate the effect of barriers on lampreys in the Coastal Oregon Province. Electrofishing surveys were conducted by a two-person field crew from July through October, 2012. Sampling occurred in two small wilderness basins and streams in the Siuslaw, Umpqua, and Coos river basins. Streams channels ranged from 0.8 to 20 m wetted width and contained no known barriers to upstream migratory fish passage. Pacific lamprey larvae occupied all streams in the sample frame and overlapped substantially with Western brook lamprey in longitudinal distribution patterns. Detection probability of larvae in the low abundance state was high (p1=0.85). Larvae in general were more likely to occupy pools than fast-water units and were rarely detected in high abundance in fast-water units. Pacific larvae were more abundant and occupied a greater proportion of the sample sites compared to Western brook larvae. Pacific lamprey larvae were detected in stream channels as small as 4 m wide. Larval occupancy and detection estimates obtained in this study are useful for designing future studies. Several improvements to the study design will lead to more precise estimates and greater scope of inference in continued research into larval distribution in small stream channels.Steve Starcevich and Shaun Clements (Native Fish Investigations Program, Corvallis Research Lab, Oregon Department of Fish and Wildlife).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 19-22).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Herpes simplex virus type 1 blocks the apoptotic host cell defense mechanisms that target Bcl-2 and manipulates activation of p38 mitogen-activated protein kinase to improve viral replication [Retracted]
No full textVolume 75, No. 6, pages 2710–2728, https://doi.org/10.1128/JVI.75.6.2710-2728.2001. George Zachos, the first author in this paper, said: “I was informed that an investigation by the University of Glasgow found that the Western blots shown in Fig. 1, 2, and 4 contain duplications; as such, the data and its interpretation are misleading and unreliable. Given the age of the publication the original full blots are no longer available. For these reasons, we retract the article and apologize for the inconvenience it may have caused to the readers.”
Joe Conner, Chris M. Preston, and Margy Koffa could not be reached for approval of this Retraction, and J. Barklie Clements is deceased
Review of \u3ci\u3e Native American Verbal Art: Texts and Contexts\u3c/i\u3e by William M. Clements
No full textIn addressing what its author calls The Ethnopoetics Movement, this sensible, well-researched volume demonstrates that recording Native American verbal art is not a new enterprise, tracing it back to seventeenth-century Jesuit records and following it through the present-day. Nor has the task of converting tribal discourse to literature ever been easy. Along with the inevitable hazards of translation, cultural barriers intrude, especially in the transfer of oral performance to the silent page. William Clements lays a clear foundation for a reasonable perspective. Earlier commentators, he writes, uncritically assumed that printed records of orally-based tribal material provide absolutely reliable information about the nature of American Indian oral expression, even its aesthetic qualities. At the opposite extreme, many modern students have dismissed these records as utterly worthless. Wisely, Clements takes a middle ground between these positions, asserting that while older texts may show limitations, in many cases they represent all we have from an entire verbal heritage. Instead of rejecting them outright, as many critics today are apt to do with the glib certitude of postcolonial hindsight, he reviews them open-mindedly, seeing the history of Native American text retrieval as a story worth knowing
Quantitative proteome responses to oncolytic reovirus in GM-CSF- and M-CSF-differentiated bone marrow-derived cells
No full textThe efficacy of oncolytic viruses (OVs), such as reovirus, is dictated by host immune responses, including those mediated by the pro- versus anti-inflammatory macrophages. As such, a detailed understanding of the interaction between reovirus and different macrophage types is critical for therapeutic efficacy. To explore reovirus–macrophage interactions, we performed tandem mass tag (TMT)-based quantitative temporal proteomics on mouse bone marrow-derived macrophages (BMMs) generated with two cytokines, macrophage colony stimulating factor (M-CSF) and granulocytic–macrophage colony stimulating factor (GM-CSF), representing anti- and proinflammatory macrophages, respectively. We quantified 6863 proteins across five time points in duplicate, comparing M-CSF (M-BMM) and GM-CSF (GM-BMM) in response to OV. We find that GM-BMMs have lower expression of key intrinsic proteins that facilitate an antiviral immune response, express higher levels of reovirus receptor protein JAM-A, and are more susceptible to oncolytic reovirus infection compared to M-BMMs. Interestingly, although M-BMMs are less susceptible to reovirus infection and subsequent cell death, they initiate an antireovirus adaptive T cell immune response comparable to that of GM-BMMs. Taken together, these data describe distinct proteome differences between these two macrophage populations in terms of their ability to mount antiviral immune responses.Canadian Cancer Society Research InstituteCanadian Institutes of Health ResearchTerry Fox Research InstituteQEII Health Sciences Centre Foundatio
Improving P2P keyword search by combining .torrent metadata and user preference in a semantic overlay
No full textDeveloping a new similarity function for Tribler. Solution used a combination of item-item and user-user similarity, using metadata available in the .torrent files to reduce sparcity in dataset.Parallel and Distributed Systems groupElectrical Engineering, Mathematics and Computer Scienc
Personalised Access to Social Media
No full textOn many websites users can personally contribute information, ranging from short text messages to photos and videos. Users can see the information contributed by others and respond to it. These social media actively engage their community in the structuring of the collection by making use of collaborative annotation methods. Next to an improved description of the collection, collaborative annotations give insight in the personal preferences of individual users. Through all interactions with the data, users leave traces that can be exploited by the system to learn this preference and personalise social media access for each individual. This thesis contributes to the understanding of social media and collaborative annotation data by studying various data filtering tasks. Different types of collaborative annotations are used to adapt the collection access to the preference of individual users. The deployed data filtering methods are used as a means to learn about the factors that contribute to the accessibility of the information in the system. The results in this thesis show that small variations in data type, user interface and other system aspects appear to have large influence on the access possibilities of social media. By increasing the understanding of collaborative annotation data and the aspects that influence this data, this thesis has been able to improve existing data filtering methods and propose new opportunities for effective personalised access to social media.MediamaticsElectrical Engineering, Mathematics and Computer Scienc
Implications for monitoring design and population persistence in dynamic stream environments
No full textFisheries management and conservation strategies often rely on an understanding of the abundance of target species. However, providing precise estimates of abundance for species or populations can require a considerable amount of effort in terms of time, or personnel, or both. During protracted sampling events, fish may be moving throughout the target study system, and if these movements are non-random they may bias abundance estimates when not accounted for by sample design. The objective of this study was to evaluate whether spatio-temporal variability in fish distribution and density of redband trout in Rock Creek, Oregon, may bias population-level abundance estimates. Specific emphasis was placed on spatio-temporal variability in distribution and density associated with stream drying. We estimated that the wetted habitat available to redband trout in Rock Creek decreased substantially from 3 June to 2 September 2015. During this time period, we sampled a total of 620 redband trout and uniquely tagged 481 redband trout. We observed movement of six tagged redband trout among samples sites (i.e., 100-m stream reaches) during the study; four fish were recaptured about 0.1 km from their original capture location, one fish was recaptured about 0.2 km from its original capture location, and one fish was recaptured about 1.8 km from its original capture location. Additionally, we did not observe any redband trout among 22 sample sites in the lower 13.1 km of Rock Creek that were sampled prior to desiccation in 2015; despite the fact that redband trout have been observed in this area during previous surveys conducted from 2007 - 2012. Over the sample period we estimated that redband trout abundance decreased from a high of 1,487 individuals to a low of 665 individual. These estimates represent about a 90% decrease in population abundance compared to previous surveys (i.e., surveys conducted from 2007 - 2012); although there were some differences in sampling methodology. Combined, these data suggest that redband trout in Rock Creek are generally not redistributing in response to stream drying, but are likely becoming stranded and die as stream habitats fragment and dry. Additionally, the number of successive years of drought or near-drought conditions, and not just the magnitude of drought in any one year, may contribute the ability to redband trout to recolonize previously dry habitats and may greatly influence the abundance of redband trout. Finally, understanding patterns of stream drying may aid in identifying drought-resistant refuge habitats that warrant special protection.Michael H. Meeuwig and Shaun P. Clements (Oregon Department of Fish and Wildlife - Native Fish Investigations Program).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page 13).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
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