175 research outputs found

    Think-tanks of the new right : theory, practice and prospects

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    The purpose of this study is to examine the role and significance for British public policy of four New Right think-tanksin recent years - namely, the Institute of Economic Affairs, the Adam Smith Institute, the Centre for Policy Studies and the Social Affairs Unit. In attempting to bring political theory into closer contact with issues of government and public policy, the thesis is intended to fill what seems to me to be an important gap in the existing literature on the New Right in Britain and is to my knowledge the first (and so far, the only) detailed study of the institutional significance or otherwise of New Right think-tanks during the 1980s in philosophical and in policy terms. The thesis is organised in the following way. Part 1 considers the differences between the think-tanks in both philosophical and policy terms, by looking at the ideological orientation and modus operandi of each in turn. Part 2 examines the impact (if any) of New Right think-tanks on Conservative health and education policy during the 1980s and considers the response of each think-tank to the issue/dilemma of welfare-dependency. Part 3 discusses the increasing importance of New Right think-tanks in Conservative Party policy-making after 1975, both in opposition (before 1979) and in office (after 1979) under Margaret Thatcher's leadership. The final chapter considers what the future `prospects' for New Right think-tanks might be, given Thatcher's departure as Prime Minister and as Leader of the Conservative Party.</p

    [Elmer Kelton, Mr. and Mrs Claude Denham at Ranching Heritage Center, undated]

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    Undated slide of author Elmer Kelton with Mr. and Mrs Claude Denham near an unidentified building at Ranching Heritage Center

    WomenEd

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    @WomenEdNE is very excited to welcome three recently published female authors. Sarah Martin Denham (with Steve Watts) is the author of The SENCO Handbook, Leading Provision and Practice published by Corwin. This Handbook gives aspiring and practising SENCOs, teachers, Headteachers and Governors an in-depth knowledge and understanding of effective policy, provision and practice to meet the diverse needs of children with special educational needs and disabilities

    Commentaries

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    Commentaries by Jack E. Davis, with Thomas Castillo, Jay Clune, James M. Denham, Russell D. James, Alex Lichtenstein, Dave Nelson, Joshua Parker, and Lee L. Willis II

    The Functionality of the Biomechanical Prosthetic Finger When Compared to Standardized and Nonstandardized Assessments

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    Abstract Date Presented 3/31/2017 The purpose of this study was to examine the functionality of the biomechanical prosthetic finger. The researchers believe this study provides therapists with evidence to support using this prosthetic as an option for clients with digit amputations. Primary Author and Speaker: Susan Denham Additional Authors and Speakers: Taylor Hawkins, Kelsey Johnson, Jenna Rhoads, Sara Sims</jats:p

    Investigating gut contents of the leptocleidian plesiosaur <i>Umoonasaurus demoscyllus</i> using micro-CT imaging

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    The holotype of Umoonasaurus demoscyllus (AM F.99374) is one of the most complete plesiosaur skeletons ever discovered in Australia. It preserves a gastric mass in the pectoral girdle region that has not yet been documented in detail. Here, we use high resolution micro-computed tomography (micro-CT) to image the gut contents of this specimen. These comprise 17 vertebrae from an unidentified teleost, together with at least 60 rounded gastroliths averaging about 5 mm in maximum length. Our study demonstrates the potential for 3D tomographic imaging to investigate Mesozoic marine reptile diets and ecology. Joshua M. White [[email protected]], Research School of Physics, Department of Materials Physics, Australian National University, Canberra, ACT 2601, Australia; Australian Museum Research Institute, 1 William Street, Sydney, New South Wales 2010, Australia. Aleese Barron [[email protected]], Research School of Physics, Department of Materials Physics, Australian National University, Canberra ACT, 2601, Australia; School of Archaeology and Anthropology, Banks Building, Australian National University, Canberra, ACT 2601, Australia. Matthew R. McCurry [[email protected]], Australian Museum Research Institute, 1 William Street, Sydney, New South Wales 2010, Australia; Earth and Sustainability Science Research Centre, School of Biological, Earth and Environmental Sciences, University of New South Wales 2052, Australia; Paleobiology, National Museum of Natural History, Smithsonian Institution, Washington, DC 20560, USA. Tim Denham [[email protected]], School of Archaeology and Anthropology, Banks Building, Australian National University, Canberra, ACT 2601, Australia.</p

    Lack of association between PBMC telomere length and endurance exercise

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    Telomeres are repetitive DNA located at the ends of chromosomes that preserve genomic stability. Excessive leukocyte telomere shortening is associated with cardio-metabolic disease and increased mortality risk. Although most studies indicate exercise training could attenuate leukocyte telomere attrition, data is somewhat equivocal. The inconsistencies could be partly explained by the different populations of leukocytes isolated for telomere length assessment. Accordingly, average peripheral blood mononuclear cell (PBMC) and whole blood leukocyte telomere length were assessed in 44 endurance athletes and 40 healthy controls using quantitative PCR. While whole blood leukocyte telomeres were, on average, 6.1% longer in endurance athletes compared to controls, PBMC telomere length was similar between the two cohorts in age and sex-adjusted analyses (athletes vs controls, mean T/S ratio ± SE: 3.25 ± 0.05 vs 3.23 ± 0.05, p = 0.72). Other than a weak inverse correlation with sitting (r = -0.25, p = 0.03), no statistically significant correlations were found between PBMC telomere length and exercise parameters. Unlike whole blood leukocytes, PBMC telomere length is not associated with endurance exercise and exercise parameters. These findings suggest the need for future work to quantify short and long telomeres of sorted immune cell populations and to measure them in context with cell counts and exercise traits

    Muscle-Enriched MicroRNAs Isolated from Whole Blood Are Regulated by Exercise and Are Potential Biomarkers of Cardiorespiratory Fitness

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    MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally. Evidence indicating miRNAs influence exercise-induced health and performance adaptations is mounting. Circulating miRNAs are responsible for intercellular communication and could serve as biomarkers for disease and exercise-related traits. Such biomarkers would contribute to exercise screening, monitoring, and the development of personalized exercise prescription. Accordingly, we investigated the impact of long-term strenuous aerobic exercise training and a single bout of maximal aerobic exercise on five muscle-enriched miRNAs implicated in exercise adaptations (miR-1, miR-133a, miR-181a, miR-486, and miR-494). We also determined linear correlations between miRNAs, resting heart rate, and maximum oxygen uptake (V˙O2 max). We used TaqMan assay quantitative polymerase chain reaction to analyze the abundance of miR-1, miR-133a, miR-181a, miR-486, and miR-494 in resting whole blood of 67 endurance athletes and 61 healthy controls. Relative to controls, endurance athletes exhibited increased miR-1, miR-486, and miR-494 content (1.26- to 1.58-fold change, all p < 0.05). miR-1, miR-133a, and miR-486 were decreased immediately after maximal aerobic exercise (0.64- to 0.76-fold change, all p < 0.01) performed by 19 healthy, young men (20.7 ± 2.4 years). Finally, we observed positive correlations between miRNA abundance and V˙ O2 max (miR-1 and miR-486) and an inverse correlation between miR-486 and resting heart rate. Therefore, muscle-enriched miRNAs isolated from whole blood are regulated by acute and long-term aerobic exercise training and could serve as biomarkers of cardiorespiratory fitness. © 2016 Denham and Prestes
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