1,735,149 research outputs found
Marion Mahony Griffin at Castlecrag, New South Wales, 27 July 1930 [picture] /
No full textTitle devised by cataloguer based on inscription.; Part of the collection: Jorma Pohjanpalo collection of photographs of Sydney and Queensland, 1928-1931.; Inscription: "Mrs. Griffin in front of home at Castlecrag, Sydney, July 27 1930. Photo by: Jorma Pohjanpalo (Finland)"--In blue ink on reverse.; Condition: Creases, yellowing.; Also available online at: http://nla.gov.au/nla.pic-vn5758135
Decolonising Antiracism: A Collective Intervention in Race, Resistance, & Identity
No full textThis article argues that any antiracist initiative that continues to rely on upholding the colonial fiction and practices of human “races” merely repackages Eurocolonial domination. Drawing on decolonial theory, epistemic-justice scholarship, African and Africana philosophies of relation, and the togetherness Wayfinder framework, the HARMONY model, and Justice AI GPT, we demonstrate how contemporary antiracism frequently reproduces the very hierarchies it seeks to dismantle while presenting alternative pathways toward a future without racism. We synthesise perspectives from Sheena Michele Mason, Shayla Sima Dube, and Christian Ortiz to outline a paradigm that lends itself to the abolition of the belief in and practice of race, and thereby racism itself, without erasing culture, lineage, or collective struggle. Our contribution is fourfold: (1) a brief genealogy of “racelessness” in African and Africana thought, (2) a critique of epistemicide and “white-comfort engineering” that co-opts liberation discourses, (3) an exposition of “racelessness” as the logical endpoint of antiracism, and (4) a practical roadmap for reclaiming identity and creating a future without antiblack racism through land, language, and lineage
Preventive and Pharmacological Interventions for Stroke: A Narrative Review of Evidence, Challenges, and Future Directions
No full textStroke remains one of the leading causes of death and long-term disability worldwide, exerting a significant burden on individuals, healthcare systems, and economies. Preventive strategies are critical in reducing the incidence and recurrence of stroke, especially among populations at high risk due to modifiable and non-modifiable factors. This narrative review synthesizes current evidence on pharmacological and non-pharmacological interventions aimed at stroke prevention. It begins by examining key modifiable risk factors, such as hypertension, smoking, excessive alcohol consumption, and physical inactivity. Hypertension, in particular, is highlighted as the most impactful risk factor, with studies showing that even modest reductions in blood pressure can significantly decrease stroke risk. Similarly, smoking cessation and regular physical activity are strongly associated with a reduced likelihood of stroke events. The review also explores pharmacological measures, including antiplatelet and anticoagulant therapies. Aspirin remains a widely used antiplatelet agent, especially in secondary prevention, although its efficacy must be balanced against potential bleeding risks. Alternatives like clopidogrel and combinations such as dual antiplatelet therapy (DAPT) are examined considering recent clinical trial evidence. In patients with atrial fibrillation, anticoagulants such as warfarin and newer direct oral anticoagulants (DOACs) like apixaban have demonstrated effectiveness in reducing stroke risk with varying safety profiles. This review identifies ongoing challenges, including patient adherence, personalized therapy decisions, and the need for broader public health implementation of preventive strategies. It concludes by highlighting the importance of integrating lifestyle interventions with individualized pharmacological treatments to optimise stroke prevention. Further research is recommended to refine these strategies and address existing gaps in knowledge, particularly in low-resource settings where the stroke burden continues to rise
Xenobiotic Distribution: A Comprehensive Review and Toxicological Implications
No full textXenobiotics is derived from the Greek words ‘Xenos’, meaning foreign and strange, and ‘bios’, which means life. Concerning the environment, xenobiotics can be defined as chemically synthesized compounds that do not occur in nature and thus are ‘foreign’ to the biosphere. Relating to the organisms, a xenobiotic is any substance foreign to life/living organism. Thus, a xenobiotic is a foreign chemical substance found within an organism that is not naturally produced by or expected to be present within the organism. The definition of xenobiotics as compounds ‘foreign to life’ exhibiting unnatural structural features does not necessarily mean that they are toxic compounds, but many are indeed harmful to living organisms. Specifically, drugs such as antibiotics are xenobiotics are xenobiotics because the human body does not produce them itself, nor are they part of a normal food. Natural compounds can also become xenobiotics if another organism takes them up. The body removes xenobiotics by xenobiotic metabolism, which consists of their deactivation and excretion, which happens mostly in the liver. Enzymes are involved in the metabolism of xenobiotics. Excretion routes are urine, feces, breath, and sweat. Xenobiotics may be grouped as carcinogens, drugs, environmental pollutants, food additives, hydrocarbons, and pesticides
Diagnostic clarity: Re-evaluating a clinical case for social anxiety disorder diagnosis in comorbid presentations
No full textDiagnostic clarity plays a vital role in the effective treatment and recovery of individuals with anxiety disorders. Social Anxiety Disorder (SAD) and Generalized Anxiety Disorder (GAD) frequently co-occur, yet SAD often remains undiagnosed in individuals who are primarily identified with GAD. This oversight can exacerbate the symptoms of both disorders, thus complicating treatment and hindering recovery. This paper explores the impact of missed comorbid diagnoses through a case study of "Rex", an individual initially diagnosed with GAD. Using a qualitative method, this paper draws on personal narratives to examine Rex’s experiences. Findings reveal that Rex’s symptoms align closely with the diagnostic criteria for SAD as outlined in the DSM-5-TR, despite the absence of a formal SAD diagnosis. The analysis highlights how the unrecognised presence of SAD contributed to persistent social avoidance, and the heightening of the symptoms of both disorders, causing functional impairment and poorer treatment outcomes. This paper highlights the importance of comprehensive diagnostic assessments in anxiety disorders, particularly when symptoms of GAD and SAD overlap. It advocates for the implementation of treatment strategies that target social fears in SAD. Furthermore, it was recommended that periodical reassessments become an integral part of care plans to be sure that no evolving or missed symptoms are left uncaptured. By emphasising the significance of diagnostic precision and personalised care, this paper contributes to a more nuanced understanding of anxiety comorbidity and its implications for mental health practice
Johdanto ja yleiskuvaus
No full textJulkaisu myös englanninkielisenä: Introduction and overview. Selected nutrients, natural antioxidants and chemical contaminants in Finnish food. Jorma Kumpulainen (Ed.)vokEK
Evaluating the use of prone positioning for young children with acute respiratory distress syndrome
No full textAcute respiratory distress syndrome (ARDS) refers to a severe condition in which the lungs fail to provide enough oxygen to vital organs of the body (NHS, 2020), and it is usually linked with multiple organ failure (Matthay, Ware, & Zimmerman, 2012). Aim: To evaluate the use of prone positioning for young children with acute respiratory distress syndrome. This review follows the Cochrane Collaboration protocol framework and uses a comprehensive search strategy across databases, including CINAHL Plus, Medline via PubMed, and Cochrane Library. Despite conflicting evidence, most studies indicate that prone positioning enhances oxygen levels and reduces mortality in severe ARDS cases
The psychological impact of COVID‐19 on students and academics at a Higher Education Institution in the United Kingdom
No full textThis study investigates the psychological impact of COVID‐19 on students and academics at a Higher Education Institution in the UK. We used critical reflective writing, in which ten students and ten lecturers wrote a short reflection (approximately 200 words) on their experience of the lockdown prior to the study. Secondly, transcriptions were gathered for analysis. Inductive Thematic Analysis was selected as the preferred method of investigation to identify, analyse, and report themes from the dataset. The specific study aims were: (a) to present an empirical investigation into the psychological impact of COVID‐19, (b) to explore the interplay between social isolation and mental health, and (c) to examine how the affected individuals understand their experiences. The health impact of COVID-19 included physiological and mental health aspects and reflected the importance of teacher and student psychological wellbeing for teaching and learning. The paper highlights that there is a need for psycho-social crisis prevention and intervention models tailored to support students\u27 and academics\u27 psychological wellbeing, arguing that considerations should be made to adjust expectations from students in relation to progression, and staff, in relation to workload
Bacteriological Examination of Water from Different Sources in a Tertiary Institution in Nigeria
No full textWater, composed of two hydrogen atoms and one oxygen atom, is the only naturally occurring inorganic liquid and remains the most abundant, essential, and indispensable resource on Earth. This study aimed to conduct a bacteriological assessment of water from four distinct sources within Ambrose Alli University (AAU), Ekpoma, Edo State. The sources investigated were: the AAU Dam, hostel water tanks, sachet water, and bottled water. Results indicated that the AAU Dam water exhibited the highest total bacterial count at 8.0 × 10⁴ cfu/mL, followed by hostel tank water (6.4 × 10⁴ cfu/mL), bottled water (5.6 × 10⁴ cfu/mL), and sachet water, which had the lowest count at 3.2 × 10⁴ cfu/mL. The most probable number (MPN) of coliforms per 100 mL ranged from 24 to 92, with the AAU Dam showing the highest value. Antibiotic susceptibility testing revealed that Ciprofloxacin, Augmentin, Pefloxacin, Tarivid, and Sparfloxacin exhibited 100% effectiveness against all bacterial isolates, while Amoxicillin showed intermediate activity. Notably, Staphylococcus aureus displayed resistance to four antibiotics. The presence of pathogenic bacteria in these water sources underscores a significant public health concern. It is recommended that all water sources—including tap, borehole, sachet, and bottled water—be adequately treated before consumption. Regulatory agencies such as NAFDAC should enforce strict compliance with water safety standards, particularly in the production and distribution of packaged sachet water. Achieving this objective requires a coordinated effort among manufacturers, consumers, and the government to safeguard public health
- …
