10,108 research outputs found
Jones, T Neil (Thomas Neil), Singapore
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/395931Surname: JONES. Given Name(s) or Initials: T NEIL (THOMAS NEIL). Military Service Number or Last Known Location: SINGAPORE. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 18365.231173
Item: [2016.0049.28224] "Jones, T Neil (Thomas Neil), Singapore
Clarence Jones and Neil O'Donnell versus West Virginia, 1989
No full textClarence Jones and Neil O'Donnell vs. West Virginia, 1989
Facing the Future: the Changing Shape of Academic Skills Support at Bournemouth University
No full textThis paper explores the potential impact of changes to higher education in England on student expectations, engagement, lifestyles and diversity, and outlines implications for the development of digital literacy within academic skills support at Bournemouth University (BU). We will investigate how tackling resource constraints with organisational change can also enable efficient, centralised provision of support materials that utilise networks to overcome the risk of fragmented support for digital literacy. We will also look at how changing delivery modes for support can accommodate changing student lifestyles whilst tackling a weakness of centralised support for digital literacy: that it can become detached from the student’s subject-focused academic practice. Finally we will explore how involving students in developing support can help us to face changes to student expectations and engagement whilst ensuring that materials are authentic and speak to learners in their own voice
Gordon Menchions, Garfield Menchions, Duncan Menchions, Joe Jones.
No full textHouse in Bishop’s Cove Shore that Betty Neil grew up in. Gordon Menchions, Garfield Menchions, Duncan Menchions (brothers), and Joe Jones (friend)
A study into exclusions for learners attending maintained specialist schools in Wales
No full textThe lasting negative implications of school exclusions on vulnerable learner’s life chances are well documented. Despite the ample research which highlights the harmful trajectory exclusions can set learners on, school exclusion data in both Wales and England remains disproportionately higher for learners with additional learning needs.
Therefore, this study aimed to further scrutinise school exclusions within the maintained specialist settings in Wales. Contact was made with the gatekeepers in the 40 maintained specialist settings in Wales to invite staff to complete a questionnaire and semi-structured interview.
The aims of this study were to:
• Explore staff perceptions of school exclusions and learn more about their professional perspectives with regards to behaviours that might warrant an exclusion.
• Further explore staff perceptions of protective factors which were in place that would help mitigate the need to resort to exclusions.
• Lastly, explore the challenges encountered by staff in their setting that may enhance the risk of requiring an exclusion to be used as a result of concerning behaviours.
Over the course of this study, staff from eight different schools participated. Although a small study, respondents from different localities have participated and were not confined to one particular geographic locality in Wales. Consequently, it is suggested that this study recruited a representative sample of educational professionals who work in Welsh maintained special schools.
Data was gathered through questionnaires and semi-structured interviews. These were then coded to identify emergent themes. The data revealed that the most important identified protective factors were the fostering of positive relationships and staff specialist knowledge. The most prevalent challenges indicated by staff were complexity of learner need, issues arising from home and staffing.
Based on the findings, recommendations have been made for future research which would help shed further light on the complexities surrounding school exclusion in maintained specialist settings
Rationale and design of a trial to personalize risk assessment in familial coronary artery disease
No full textAbstract not availableThomas H Marwick, Kristyn Whitmore, Stephen J Nicholls, Tony Stanton, Geoffrey Mitchell, Andrew Tonkin, Christopher Blizzard, Amanda Neil, Catherine Jones and Gerald F Watts, on behalf of the CAUGHT-CAD investigator
Design and development of specific antisense probes against the major protein kinase B isoforms
No full textThe study of cell signalling is important in elucidating the roles of many proteins in cellular functions. Signalling factors such as insulin act via receptor mediated transduction cascades to bring about a variety of effects including controlling translation, metabolic regulation and the cell cycle. Most of these effects are mediated by phosphorylation of serine, threonine or tyrosine residues of proteins and hence protein kinases have a crucial role to play in regulation One such important signal transduction protein is the serine/threonine kinase; protein kinase B (PKB) which is also referred to as Akt. PKB was discovered in 1990 and is a 60kDa cytosolic protein with 3 known isofbrms (a, p, y). PKB has been shown to be activated in response to a variety of & ctars including insulin, EGF and PDGF, and this activation has been shown to involve PI 3 kinase and the recently discovered kinase, PDKl. To date PKB has been proposed to be involved in the regulation of many cellular processes including: apoptosis, protein synthesis and insulin stimulated glucose/glycogen metabolism. Possible roles for PKB include the translocation of GLUT4 transporters to the plasma membrane, inhibition of glycogen synthase kinase-3 (GSK-3) and activation of S6 kinase. PKB has also been proposed to act as a survival factor. Direct evidence for these and other roles for PKB is still lacking and is now urgently sought. Towards this objective I have developed, 2 eSective antisense oligcmucleotides speciGc for eidier the a or p isofbrms of PKB, which have been shown to d^ Ids the levels of that iso & rm by over 90% in 3T3-L1 fibroblasts and adipoctyes. Optimum conditions (time/concentration) have now beei laid down for these 2 probes and by using various ccmtrol oligonucleotides (sense, random and mismatch) I have shown these probes to be both speciSc and very effective inhibitors of each target PKB isofbrm. Using these probes 1 have already established a critical role for PKBa in the differaitiation of cells (3T3-L1 fibroblasts to adipocytes). Use of these probes also suggests that PKBd and PKBP are not involved in the growth factor induced phosphorylation and activation of S6 kinase in the cell lines tested. A suitable peptide based assay for analysing the activation of GSK-3 was developed and preliminary studies into the position of GSK-3 in signalling pathways undertaken. A specific PKBy antisense probe has also been devised and is currently under test. As the developed antisense probes are the first inhibitors against PKB available, it is hoped they can be used not only to establish the roles of PKB in various complex cell processes, but also aid understanding of certain diseases which this cascade mav be involved in.</p
Why Privacy Matters: An Interview with Neil Richards
No full textProfessor Daniel J. Solove discusses the book \u27Why Privacy Matters\u27 and the future of privacy with the author, Professor Neil Richards
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