1,722,587 research outputs found
Live at Quincy's: Kevin Jones, Mark Greenhouse
No full textLive at Quincy's: Kevin Jones, Mark Greenhous
Handbook of Secondary Geography
No full textThe Handbook of Secondary Geography provides secondary school Geography teachers with important themes and issues which bring together theory and practice. Chapters include what is geography, thinking geographically, fieldwork, GIS, literacy, numeracy, research, CPD and belonging to a community of practice
Idiopathic pulmonary fibrosis: recent trials and current drug therapy
No full textIdiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease with increasing incidence; the median survival is only 35 months and as yet no therapy has been proven to prolong survival. Recent unexpected randomised controlled trial (RCT) results and the conflicting evaluations of drug efficacy by regulatory agencies when considering the approval of pirfenidone have emphasised that we remain in the first stages of both our understanding of disease-relevant therapeutic targets and in our ability to investigate these putative targets with well-designed RCT. Three phase III trials are, however, anticipated to report results in 2014 and there is cautious optimism that we may be entering an era of mechanism-based anti-fibrotic therapies proven by large RCT to modify disease progression. We must now address how to practically translate these therapies safely and with maximal efficacy from a homogenous RCT population to the 'real-life' heterogeneous population of patients with IPF. The role of a formal multi-disciplinary team meeting in a specialist centre with expertise in IPF is key to this. New methodological and ethical research challenges will arise as we enter an era of potential combination therapy; standardized, robust RCT design will be central to meeting these challenges if we are to enable ongoing progress in our aim of increasing both the length and quality of life of patients with IPF
A critical evaluation and development of the operational utility of active rotor technology
No full textDebates in geography education
No full textDebates considered include:•What constitutes knowledge in geography?•Constructing the curriculum;•How do we link assessment to making progress in geography?•The contribution of fieldwork and outdoor experiences;•Technology and media;•How we use Geographical Information;•How geography contributes to ‘global learning’;•Sustainable development and geography education.The comprehensive, rigorous coverage of these key issues, together with carefully annotated selected further reading, reflective questions and a range of specific web-based resources, will help support shape your own research and writing. Debates in Geography Education is a source of knowledge, experience and debate that will be essential reading for all students studying at Masters level, practising teachers who want to develop a better understanding of the issues that shape their practice, and Education Studies students considering in-depth subject teaching
- …
