4,112 research outputs found
Data from "Diverse Bacterial Communities Exist on Canine Skin and are Impacted by Cohabitation and Time"
No full textDataset from sampling of 40 dogs over three time points. Dogs were paired across 20 households. Data is in raw fastq format from amplicon sequencing of the V1-V3 regions of the 16S rRNA gene using Illumina MiSeq.This related study sampled 40 dogs from 20 households over the course of three seasons. Three skin sites were examined. The goal of the study was to determine if a core skin microbiome exists in dogs across time and body site, and if cohabitation impacts sharing of the skin microbiome. This dataset is a part of the Torres_Johnson Canine Microbiome Study.Morris Animal Foundation grant D13CA-037Johnson, Timothy; Torres, Sheila; Danzeisen, Jessica; Clayton, Jonathan; Ward, Tonya; Knights, Dan; Huang, Hu. (2016). Data from "Diverse Bacterial Communities Exist on Canine Skin and are Impacted by Cohabitation and Time". Retrieved from the University Digital Conservancy, http://doi.org/10.13020/D6W01V
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
The sentiments of a Church-of-England man : a study of Swift's politics
No full textThis contextualist study re-examines the contested critical
question of Jonathan Swift's political character. It is
concerned with the historical meaning of Swift's texts
and attempts to recover their original political impact.
Politically-literate contemporaries claimed to read Jacobite
Tory politics in Swift's texts. Rather than dismiss the
judgement of Swift's contemporaries, this study asks whether
there is anything about Swift's political writing in polemical
context that could have led contemporaries to construe
the politics of his texts as Jacobite Tory. The conclusion
this study reaches is that aspects of Swift's political
rhetoric are consonant with Tory and Jacobite polemic.
While contesting current conceptions of Swift as a Whig,
this study offers a partial revision of that scholarship
which describes Swift as a non-Jacobite Tory.
The thesis is based on an analysis of Swift's prose, poetry
and correspondence and contemporary (mainly printed) sources
books, pamphlets, poems on affairs of state and newspapers.
Some new or neglected polemical contexts and analogues
for Swift's works are suggested. Chapter 1 considers some
of the problems and contested issues in interpretation
of Swift's political biography and writing. Chapter 2
witnesses Swift's combination of High Church attitudes
with a radical political critique of Whig establishment.
Swift is read in juxtaposition with Jacobite Tory authors
such as George Granville, Lord Lansdowne. Chapter 3 relocates
A Tale of a Tub in historical context to reveal the satire's
relation to High Church Tory polemical languages. Chapter
4 discusses the disaffected Tory aspect of Gulliver's
Travels. Chapter 5 attempts to register the complexity
of the textual evidence of Swift's attitude to Jacobitism.
Detailed attention is given to his politically-revealing
attitudes to the Dutch. A coda briefly describes Swift's
discontent with the Revolution settlement, examines this
Church-of-England Man's sentiments on the crucial ideological
issue of resistance, and suggests the importance of Hugo
Grotius in Swift's political thought
Reviving the past : eighteenth-century evangelical interpretations of church history
No full textThis study addresses eighteenth-century English-speaking evangelicals' understandings of church history, through the lens of published attempts to represent preceding Christian centuries panoramically or comprehensively. Sources entail several short reflections on history emerging in the early years of the transatlantic Revival (1730s-1740s) and subsequent, more substantial efforts by evangelical leaders John Gillies, Jonathan Edwards, John Wesley, Joseph and Isaac Milner, and Thomas Haweis. Little scholarly analysis exists on these sources, aside from the renaissance of interest in recent decades in Edwards. This is surprising, considering the acknowledged prominence of history-writing in the eighteenth century and the influence attributed, then and now, to the works of authors such as Gibbon, Hume, and Robertson. The aim is, first, to elucidate each of the above evangelicals' interpretations of the Christian past, both in overview and according to what they said on a roster of particular historical events, people and movements, and then to consider shared and divergent aspects. These aspects range from points of detail to paradigmatic theological convictions. Secondarily, evangelical church histories are analyzed in relation to earlier Protestant as well as eighteenth-century 'enlightened' historiography, in part through attention to evangelical authors' explicit engagement with these currents. This contextualization assists in determining the unique qualities of evangelical interpretations. Is there, then, evidence of a characteristically 'evangelical' perspective on church history? An examination of this neglected area illumines patterns and particulars of evangelicals' historical thought, and these in turn communicate the self-perceptions and the defining features of evangelicalism itself. Findings support the primary contention that evangelical leaders made use of a dynamic pattern of revival and declension as a means of accounting for the full history of Christianity. Beyond displaying the central place of 'revival' for evangelicals, these church histories demonstrate evangelicalism‘s complex relationship—involving both receptivity and critique—with Protestant and Enlightenment currents of historical inquiry
Bäcklund transformations for noncommutative anti-self-dual Yang-Mills equations
No full textWe present Bäcklund transformations for the non-commutative anti-self-dual Yang–Mills equations where the gauge group is G = GL(2) and use it to generate a series of exact solutions from a simple seed solution. The solutions generated by this approach are represented in terms of quasi-determinants and belong to a non-commutative version of the Atiyah–Ward ansatz. In the commutative limit, our results coincide with those by Corrigan, Fairlie, Yates and Goddard
Veld fire management strategies in rural areas: the case of Ward 1 in Hwedza
No full textThis study sought to assess veld fire management strategies in Hwedza Ward 1. Data was collected using questionnaires, field observation and key informant interviews. Major causes of fire in the area include hunting land clearance and smoking bees. Results show that people in Ward 1 have benefited from the introduction of a veld fire management plan that was introduced by EMA in 2010. Frequency of veld fires has declined from 31 between 2005 and 2009 to 11 between 2010 and 2014. As a result there are fewer cases of property loss and death due to veld fires. The veld fire management plan includes prevention, suppression and post suppression measures to veld fires although the plan’s strength lies in veld fire prevention
Dynamics of Network Formation Processes in the Co-Author Model
No full textThis article studies the dynamics in the formation processes of a mutual consent network in game theory setting: the Co-Author Model. In this article, a limited observation is applied and analytical results are derived. Then, 2 parameters are varied: the number of individuals in the network and the initial probability of the links in the network in its initial state. A simulation result shows a finding that is consistent with an analytical result for a state of equilibrium while it also shows different possible equilibria.Dynamics, Network, Game Theory, Model,Simulation, Equilibrium, Complexity
Reading Swift and Ireland, 1720-1729 : constituences, contexts and constructions of identity in Jonathan Swift's occasional writings of the 1720s
No full textThe 1720s was a decade of crisis in Ireland. Jonathan Swift's occasional writings from these years extend the country's political and economic crises into
dramas of personal and national identity. Part One of this thesis investigates the material conditions of the relationship between Swift, his Irish audience, and the
underlying problems of identity that such an audience simultaneously poses and occludes. Part Two is an anatomy of the literary modes through which that relationship is figured.
The first chapter offers the 1720 Declaratory Act as an important subtext for Swift's 'inaugural' work of the decade, the 1720 Proposalfor the Universal Use of Irish Manufacture. Challenging retrospective constructions of the author's textual and political authority, the chapter examines how Swift the 'Hibernian patriot' was largely an invention of the crisis surrounding the act. Chapter Two
argues that The Drapier's Letters reconfigure the language that had been used in the past to depict the Catholic threat to Protestant Ireland, and use it to depict the
threat emerging from England.
Part Two moves to the question of identity, which Chapter Three designates a kind of 'style', both a mode of expression and a trend in polite society. The writing of history and the social signification of language are the
main concerns of this chapter, which investigates how Irish historiography becomes the focus for a range of concerns in the 1720s. Chapter Four nominates the pastoral genre as an alternative vehicle for the reading and writing of history
in Swift's Ireland. It identifies a Virgilian dialectic of expropriation and protection by a patron as an important method of 'reading' oneself into history and identity. Looking at various manifestations of crisis in Ireland in 1729 - famine, fuel shortages and emigration, the final chapter argues that A Modest Proposal uses techniques of allegory to produce a crisis of interpretation. By
promoting and perpetuating misreading, it mirrors the pervasive climate of error that produced this text.
As a whole the thesis documents three transitions. It traces the emergence of a parodic method of literary and political representation which eventually overwhelms any claims Swift's writing might once have made to positive
advocacy. Once considered the dominant and definitive voice of 1720s Ireland, Swift is re-appraised as one writer among many, and his writing as a product of his society rather than an authoritative comment on it. Finally, the Presbyterians of Ireland are shown to emerge by the end of the decade as the primary focus for the anxieties and aggressions that animate Swift's occasional writings
Impact of Web technologies on student-lecturer expert power relationship
No full textExpert power is “the power that comes from having knowledge and expertise in a particular area” (Nazarko, 2004). In the history of the development of higher education, the relationship between the lecturer and the students has changed because of many different factors. Before the internet and web revolution, the lecturer used to be the main information source for his/her students. The web as a modern source of knowledge is now used universally and this spreading trend might affect the relationship between the lecturer and his students. Understanding the impact of this change appears to be important as it would be employed in improving teaching techniques. In this area, many studies have focused on the impact of using the internet and web applications on students and lecturers. These studies have widely investigated this impact on student’s achievements, attitude and also have shown how the role and performance of the faculty have changed. This paper aims to investigate the impact of using web resources as a source of knowledge on the student-lecturer relationship from students’ perspectives. The investigation focuses on how students’ knowledge gained from using websites has impacted on the relationship with their lecturer as a knowledgeable person which theoretically means Expert power. 1661 students from 30 universities/ educational institutions participated in this research
Atlantic contingency : Jonathan Dickinson and the Anglo-Atlantic world, 1655-1725
No full textThis dissertation is about how Jonathan Dickinson (1663-1722), a second-generation
Anglo-Jamaican planter and early-Philadelphian merchant, made sense of the mercurial
and uncertain Atlantic world around the turn of the eighteenth century. The following
chapters examine Dickinson’s interactions with an extremely diverse group of European,
Native American, and African peoples who collectively comprised a formative
generation of colonial society in North America and the West Indies. The main purpose
of this dissertation is to provide a counterpoint to the many tautologous, whiggish, and
nationalistic interpretations of Anglo-Atlantic history that tend to deemphasise the
obvious disconnections, disruptions, discord, and diversity apparent during the lateseventeenth
and early-eighteenth centuries. This dissertation further contends that
individuals, driven by self-preservation and influenced by local circumstances, dictated
the direction and the pace of many inter-colonial, inter-imperial, and trans-Atlantic
developments familiar to the late-eighteenth century Anglo-Atlantic world. In short, new
exigencies outweighed custom, and self-preservation, rather than directives from
metropolitan governments, guided Atlantic peoples’ actions. By extension of individual
actions, the nascent British Atlantic Empire began to take shape
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